| An efficient platform for astrocyte differentiation from human induced pluripotent stem cells TCW Julia, M Wang, AA Pimenova, KR Bowles, BJ Hartley, E Lacin, ... Stem cell reports 9 (2), 600-614, 2017 | 423 | 2017 |
| ELAVL4, splicing, and glutamatergic dysfunction precede neuron loss in MAPT mutation cerebral organoids KR Bowles, MC Silva, K Whitney, T Bertucci, JE Berlind, JD Lai, JC Garza, ... Cell 184 (17), 4547-4563. e17, 2021 | 123 | 2021 |
| High-resolution temporal and regional mapping of MAPT expression and splicing in human brain development MM Hefti, K Farrell, SH Kim, KR Bowles, ME Fowkes, T Raj, JF Crary PloS one 13 (4), e0195771, 2018 | 93 | 2018 |
| A Comprehensive Resource for Induced Pluripotent Stem Cells from Patients with Primary Tauopathies CM Karch, AW Kao, A Karydas, K Onanuga, R Martinez, A Argouarch, ... Stem cell reports 13 (5), 939-955, 2019 | 89 | 2019 |
| Alzheimer's-associated PU. 1 expression levels regulate microglial inflammatory response AA Pimenova, M Herbinet, I Gupta, SI Machlovi, KR Bowles, E Marcora, ... Neurobiology of Disease 148, 105217, 2021 | 76 | 2021 |
| Kinase signalling in Huntington's disease KR Bowles, L Jones Journal of Huntington's disease 3 (2), 89-123, 2014 | 64 | 2014 |
| Reduced variability of neural progenitor cells and improved purity of neuronal cultures using magnetic activated cell sorting KR Bowles, TCW Julia, L Qian, BM Jadow, AM Goate PloS one 14 (3), 2019 | 50 | 2019 |
| 17q21. 31 sub-haplotypes underlying H1-associated risk for Parkinson’s disease are associated with LRRC37A/2 expression in astrocytes KR Bowles, DA Pugh, Y Liu, T Patel, AE Renton, S Bandres-Ciga, ... Molecular neurodegeneration 17 (1), 1-21, 2022 | 42 | 2022 |
| Gene expression and behaviour in mouse models of HD KR Bowles, SP Brooks, SB Dunnett, L Jones Brain research bulletin 88 (2-3), 276-284, 2012 | 34 | 2012 |
| Genome-wide association study and functional validation implicates JADE1 in tauopathy K Farrell, SH Kim, N Han, MA Iida, EM Gonzalez, M Otero-Garcia, ... Acta neuropathologica 143, 33-53, 2022 | 27 | 2022 |
| Dysregulated coordination of MAPT exon 2 and exon 10 splicing underlies different tau pathologies in PSP and AD KR Bowles, DA Pugh, LM Oja, BM Jadow, K Farrell, K Whitney, A Sharma, ... Acta neuropathologica 143, 225-243, 2022 | 24 | 2022 |
| SMAD transcription factors are altered in cell models of HD and regulate HTT expression KR Bowles, T Stone, P Holmans, ND Allen, SB Dunnett, L Jones Cellular signalling 31, 1-14, 2017 | 24 | 2017 |
| Mutations in α-synuclein, TDP-43 and tau prolong protein half-life through diminished degradation by lysosomal proteases PJ Sampognaro, S Arya, GM Knudsen, EL Gunderson, A Sandoval-Perez, ... Molecular Neurodegeneration 18 (1), 1-22, 2023 | 19 | 2023 |
| Some appetitive procedures for examining associative learning in the mouse: Implications for psychopathology C Bonardi, C Bartle, K Bowles, F de Pulford, DJ Jennings Behavioural brain research 211 (2), 240-247, 2010 | 17 | 2010 |
| Huntingtin Subcellular Localisation Is Regulated by Kinase Signalling Activity in the StHdhQ111 Model of HD KR Bowles, SP Brooks, SB Dunnett, L Jones PLoS One 10 (12), e0144864, 2015 | 7 | 2015 |
| The influence of 17q21. 31 and APOE genetic ancestry on neurodegenerative disease risk N Harerimana, A Goate, K Bowles Frontiers in Aging Neuroscience 14, 2022 | 5 | 2022 |
| Cell Type-Specific In Vitro Gene Expression Profiling of Stem Cell-Derived Neural Models JA Gregory, E Hoelzli, R Abdelaal, C Braine, M Cuevas, M Halpern, ... Cells 9 (6), 1406, 2020 | 5 | 2020 |
| 17q21. 31 sub-haplotypes underlying H1-associated risk for Parkinson’s disease and progressive supranuclear palsy converge on altered glial regulation KR Bowles, DA Pugh, K Farrell, N Han, J TCW, Y Liu, SA Liang, L Qian, ... BioRxiv, 860668, 2019 | 5 | 2019 |
| Cell-type specific gene expression profiling in heterogeneous in vitro cultures using epitope-tagged RPL22 JA Gregory, E Hoelzli, R Abdelaal, C Braine, M Cuevas, M Halpern, ... bioRxiv, 2020.04. 30.064709, 2020 | | 2020 |
| P1‐144: GENOME‐WIDE ASSOCIATION STUDY IN AN AUTOPSY COHORT OF PROGRESSIVE SUPRANUCLEAR PALSY N Han, KW Farrell, AE Renton, A Casella, K Bowles, MA Iida, EP Cortes, ... Alzheimer's & Dementia 15, P292-P292, 2019 | | 2019 |
Alison GoateProfessor of Genetics & Genomic Sciences, Icahn School of Medicine at Mount SinaiVerified email at mssm.edu