| SynNotch-CAR T cells overcome challenges of specificity, heterogeneity, and persistence in treating glioblastoma JH Choe, PB Watchmaker, MS Simic, RD Gilbert, AW Li, NA Krasnow, ... Science translational medicine 13 (591), eabe7378, 2021 | 360 | 2021 |
| Lipid biosynthesis coordinates a mitochondrial-to-cytosolic stress response HE Kim, AR Grant, MS Simic, RA Kohnz, DK Nomura, J Durieux, CE Riera, ... Cell 166 (6), 1539-1552. e16, 2016 | 215 | 2016 |
| HSF-1–mediated cytoskeletal integrity determines thermotolerance and life span NA Baird, PM Douglas, MS Simic, AR Grant, JJ Moresco, SC Wolff, ... Science 346 (6207), 360-363, 2014 | 184 | 2014 |
| Proteostasis and aging of stem cells D Vilchez, MS Simic, A Dillin Trends in cell biology 24 (3), 161-170, 2014 | 162 | 2014 |
| The hyaluronidase, TMEM2, promotes ER homeostasis and longevity independent of the UPRER RT Schinzel, R Higuchi-Sanabria, O Shalem, EA Moehle, BM Webster, ... Cell 179 (6), 1306-1318. e18, 2019 | 112 | 2019 |
| Heterotypic signals from neural HSF-1 separate thermotolerance from longevity PM Douglas, NA Baird, MS Simic, S Uhlein, MA McCormick, SC Wolff, ... Cell reports 12 (7), 1196-1204, 2015 | 108 | 2015 |
| Decoding CAR T cell phenotype using combinatorial signaling motif libraries and machine learning KG Daniels, S Wang, MS Simic, HK Bhargava, S Capponi, Y Tonai, W Yu, ... Science 378 (6625), 1194-1200, 2022 | 70 | 2022 |
| Prostaglandin signals from adult germline stem cells delay somatic ageing of Caenorhabditis elegans HJ Lee, A Noormohammadi, S Koyuncu, G Calculli, MS Simic, M Herholz, ... Nature metabolism 1 (8), 790-810, 2019 | 38 | 2019 |
| CAR-T cell–mediated B-cell depletion in central nervous system autoimmunity S Gupta, M Simic, SA Sagan, C Shepherd, J Duecker, RA Sobel, ... Neurology: Neuroimmunology & Neuroinflammation 10 (2), e200080, 2023 | 37 | 2023 |
| Transient activation of the UPRER is an essential step in the acquisition of pluripotency during reprogramming MS Simic, EA Moehle, RT Schinzel, FK Lorbeer, JJ Halloran, K Heydari, ... Science Advances 5 (4), eaaw0025, 2019 | 36 | 2019 |
| Endocytic trafficking determines cellular tolerance of presynaptic opioid signaling D Jullié, C Benitez, TA Knight, MS Simic, M von Zastrow Elife 11, e81298, 2022 | 16 | 2022 |
| SynNotch-CAR T cells overcome challenges of specificity, heterogeneity, and persistence in treating glioblastoma. Sci Transl Med. 2021; 13 (591) JH Choe, PB Watchmaker, MS Simic, RD Gilbert, AW Li, NA Krasnow, ... Epub 2021/04/30. PubMed PMID: 33910979, 0 | 12 | |
| Programming tissue-sensing T cells that deliver therapies to the brain MS Simic, PB Watchmaker, S Gupta, Y Wang, SA Sagan, J Duecker, ... Science 386 (6726), eadl4237, 2024 | 6 | 2024 |
| Multi-antigen recognition circuits overcome challenges of specificity, heterogeneity, and durability in T cell therapy for glioblastoma JH Choe, PB Watchmaker, MS Simic, RD Gilbert, AW Li, NA Krasnow, ... bioRxiv, 2021.01. 07.425632, 2021 | 5 | 2021 |
| The Lysosome, elixir of neural stem cell youth MS Simic, A Dillin Cell Stem Cell 22 (5), 619-620, 2018 | 4 | 2018 |
| Engineering synthetic suppressor T cells that execute locally targeted immunoprotective programs NR Reddy, H Maachi, Y Xiao, MS Simic, W Yu, Y Tonai, DA Cabanillas, ... Science 386 (6726), eadl4793, 2024 | 3 | 2024 |
| A critical reading of The Spirit Level: why equality is better for everyone, R. Wilkinson and K. Pickett M Simic CERES Department, January, 2012 | 3 | 2012 |
| Exploring the rules of chimeric antigen receptor phenotypic output using combinatorial signaling motif libraries and machine learning KG Daniels, S Wang, MS Simic, HK Bhargava, S Capponi, Y Tonai, W Yu, ... bioRxiv, 2022.01. 04.474985, 2022 | 1 | 2022 |
| 251 Engineering novel SynNotch CAR T cells to precisely and effectively target medulloblastoma MC Cove, S Lakshmanachetty, M Simic, B Ng, R Zhu, C Shepherd, ... Journal for ImmunoTherapy of Cancer 12 (Suppl 2), 2024 | | 2024 |
| Synthetic immuno-suppressive cells and methods of use thereof WA Lim, N Reddy, M Simic US Patent App. 18/294,854, 2024 | | 2024 |