| Elevated histone expression promotes life span extension J Feser, D Truong, C Das, JJ Carson, J Kieft, T Harkness, JK Tyler Molecular cell 39 (5), 724-735, 2010 | 438 | 2010 |
| Yeast histone H3 and H4 amino termini are important for nucleosome assembly in vivo and in vitro: redundant and position-independent functions in assembly but not in gene … X Ling, TA Harkness, MC Schultz, G Fisher-Adams, M Grunstein Genes & development 10 (6), 686-699, 1996 | 189 | 1996 |
| A crucial role of the mitochondrial protein import receptor MOM19 for the biogenesis of mitochondria TA Harkness, FE Nargang, I van der Klei, W Neupert, R Lill The Journal of cell biology 124 (5), 637-648, 1994 | 124 | 1994 |
| Lithocholic bile acid selectively kills neuroblastoma cells, while sparing normal neuronal cells AA Goldberg, A Beach, GF Davies, TAA Harkness, A LeBlanc, ... Oncotarget 2 (10), 761, 2011 | 111 | 2011 |
| Stimulation of the Mu A protein-mediated strand cleavage reaction by the Mu B protein, and the requirement of DNA nicking for stable type 1 transpososome formation. In vitro … MG Surette, T Harkness, G Chaconas Journal of Biological Chemistry 266 (5), 3118-3124, 1991 | 90 | 1991 |
| The yeast forkhead transcription factors fkh1 and fkh2 regulate lifespan and stress response together with the anaphase-promoting complex SDL Postnikoff, ME Malo, B Wong, TAA Harkness PLoS Genetics 8 (3), e1002583, 2012 | 85 | 2012 |
| Ssd1 and Gcn2 suppress global translation efficiency in replicatively aged yeast while their activation extends lifespan Z Hu, B Xia, SDL Postnikoff, ZJ Shen, AS Tomoiaga, TA Harkness, ... Elife 7, e35551, 2018 | 81 | 2018 |
| Metformin inhibits the development, and promotes the resensitization, of treatment-resistant breast cancer G Davies, L Lobanova, W Dawicki, G Groot, JR Gordon, M Bowen, ... PloS one 12 (12), e0187191, 2017 | 62 | 2017 |
| A functional analysis reveals dependence on the anaphase-promoting complex for prolonged life span in yeast TAA Harkness, KA Shea, C Legrand, M Brahmania, GF Davies Genetics 168 (2), 759-774, 2004 | 58 | 2004 |
| Chromatin assembly in a yeast whole-cell extract MC Schultz, DJ Hockman, TAA Harkness, WI Garinther, BA Altheim Proceedings of the National Academy of Sciences 94 (17), 9034-9039, 1997 | 55 | 1997 |
| Inactivation of the Neurospora crassa gene encoding the mitochondrial protein import receptor MOM19 by the technique of" sheltered RIP". TA Harkness, RL MetZenberg, H Schneider, R Lill, W Neupert, ... Genetics 136 (1), 107-118, 1994 | 52 | 1994 |
| Regulation of Lysosomal Function by the DAF-16 Forkhead Transcription Factor Couples Reproduction to Aging in Caenorhabditis elegans K Baxi, A Ghavidel, B Waddell, TA Harkness, CE de Carvalho Genetics 207 (1), 83-101, 2017 | 48 | 2017 |
| Development, maintenance, and reversal of multiple drug resistance: At the crossroads of TFPI1, ABC transporters, and HIF1α T Arnason, T Harkness Cancers 7 (4), 2063-2082, 2015 | 44 | 2015 |
| Troglitazone reverses the multiple drug resistance phenotype in cancer cells GF Davies, BHJ Juurlink, TAA Harkness Drug design, development and therapy, 79-88, 2009 | 43 | 2009 |
| The Ubiquitin-Dependent Targeting Pathway in Saccharomyces cerevisiae Plays a Critical Role in Multiple Chromatin Assembly Regulatory Steps TAA Harkness, GF Davies, V Ramaswamy, TG Arnason Genetics 162 (2), 615-632, 2002 | 42 | 2002 |
| The role of Anaphase Promoting Complex activation, inhibition and substrates in cancer development and progression C VanGenderen, TAA Harkness, TG Arnason Aging (Albany NY) 12 (15), 15818, 2020 | 38 | 2020 |
| A simplified method for measuring secreted invertase activity in Saccharomyces cerevisiae AA Harkness Troy, G Arnason Terra Biochemistry & Pharmacology 3 (151), 2167-0501, 2014 | 36 | 2014 |
| Troglitazone overcomes doxorubicin-resistance in resistant K562 leukemia cells GF Davies, WJ Roesler, BHJ Juurlink, TAA Harkness Leukemia & lymphoma 46 (8), 1199-1206, 2005 | 36 | 2005 |
| Disruption of the nuclear gene encoding the 20.8-kDa subunit of NADH:ubiquinone reductase ofNeurospora mitochondria MV da Silva, PC Alves, M Duarte, N Mota, A Lobo-da-Cunha, A Videira, ... Molecular and General Genetics MGG 252, 177-183, 1996 | 36 | 1996 |
| A genome scale screen for mutants with delayed exit from mitosis: Ire1-independent induction of autophagy integrates ER homeostasis into mitotic lifespan A Ghavidel, K Baxi, V Ignatchenko, M Prusinkiewicz, TG Arnason, ... PLoS genetics 11 (8), e1005429, 2015 | 33 | 2015 |
