Single-cell proteomic and transcriptomic analysis of macrophage heterogeneity using SCoPE2 H Specht, E Emmott, AA Petelski, RG Huffman, DH Perlman, M Serra, ... Genome biology 22, 1-27, 2021 | 442 | 2021 |
Ribosome levels selectively regulate translation and lineage commitment in human hematopoiesis RK Khajuria, M Munschauer, JC Ulirsch, C Fiorini, LS Ludwig, ... Cell 173 (1), 90-103. e19, 2018 | 382 | 2018 |
Multiplexed single-cell proteomics using SCoPE2 AA Petelski, E Emmott, A Leduc, RG Huffman, H Specht, DH Perlman, ... Nature protocols 16 (12), 5398-5425, 2021 | 182 | 2021 |
Quantitative, multiplexed workflow for deep analysis of human blood plasma and biomarker discovery by mass spectrometry H Keshishian, MW Burgess, H Specht, L Wallace, KR Clauser, MA Gillette, ... Nature protocols 12 (8), 1683-1701, 2017 | 181 | 2017 |
Increasing the throughput of sensitive proteomics by plexDIA J Derks, A Leduc, G Wallmann, RG Huffman, M Willetts, S Khan, H Specht, ... Nature biotechnology 41 (1), 50-59, 2023 | 180 | 2023 |
Transformative opportunities for single-cell proteomics H Specht, N Slavov Journal of Proteome Research 17 (8), 2565-2571, 2018 | 140 | 2018 |
Automated sample preparation for high-throughput single-cell proteomics H Specht, G Harmange, DH Perlman, E Emmott, Z Niziolek, B Budnik, ... BioRxiv, 399774, 2018 | 74 | 2018 |
Prioritized mass spectrometry increases the depth, sensitivity and data completeness of single-cell proteomics RG Huffman, A Leduc, C Wichmann, M Di Gioia, F Borriello, H Specht, ... Nature methods 20 (5), 714-722, 2023 | 64 | 2023 |
DO-MS: data-driven optimization of mass spectrometry methods RG Huffman, A Chen, H Specht, N Slavov Journal of Proteome Research 18 (6), 2493-2500, 2019 | 62 | 2019 |
Single-cell mass-spectrometry quantifies the emergence of macrophage heterogeneity H Specht, E Emmott, AA Petelski, R Gray Huffman, DH Perlman, M Serra, ... BioRxiv 10, 665307, 2019 | 59 | 2019 |
Optimizing accuracy and depth of protein quantification in experiments using isobaric carriers H Specht, N Slavov Journal of Proteome Research 20 (1), 880-887, 2020 | 58 | 2020 |
Prioritized single-cell proteomics reveals molecular and functional polarization across primary macrophages RG Huffman, A Leduc, C Wichmann, M di Gioia, F Borriello, H Specht, ... BioRxiv, 2022.03. 16.484655, 2022 | 16 | 2022 |
Single-cell proteomic and transcriptomic analysis of macrophage heterogeneity H Specht, E Emmott, AA Petelski, RG Huffman, DH Perlman, M Serra, ... BioRxiv, 665307, 2019 | 15 | 2019 |
A highly multiplexed quantitative phosphosite assay for biology and preclinical studies H Keshishian, ER McDonald III, F Mundt, R Melanson, K Krug, DA Porter, ... Molecular Systems Biology 17 (9), e10156, 2021 | 14 | 2021 |
TAILS identifies candidate substrates and biomarkers of ADAMTS7, a therapeutic protease target in coronary artery disease BT MacDonald, H Keshishian, CC Mundorff, A Arduini, D Lai, K Bendinelli, ... Molecular & Cellular Proteomics 21 (4), 2022 | 13 | 2022 |
Single-cell proteomics preparation for mass spectrometry analysis using freeze-heat lysis and an isobaric carrier AA Petelski, N Slavov, H Specht Journal of visualized experiments: JoVE, 10.3791/63802, 2022 | 10 | 2022 |
BCG vaccination of Diversity Outbred mice induces cross-reactive antibodies to SARS-CoV-2 spike protein AG Specht, SL Kurtz, KL Elkins, H Specht, G Beamer bioRxiv, 2022.04. 18.488640, 2022 | 3 | 2022 |
Beyond Protein Sequence: Protein Isomerization in Alzheimer’s Disease H Specht, N Slavov Journal of proteome research 21 (2), 299, 2022 | 3 | 2022 |
How to perform quantitative single cell proteomics with SCoPE2 E Emmott, RG Huffman, P Kharchenko, A Koller, DH Perlman, A Petelski, ... Journal of biomolecular techniques: JBT 31 (Suppl), S35, 2020 | 2 | 2020 |
Single-cell mass-spectrometry quantifies the emergence of macrophage heterogeneity. bioRxiv 665307 H Specht, E Emmott, AA Petelski, R Gray Huffman, DH Perlman, M Serra, ... | 2 | 2019 |