Microscale culture of human liver cells for drug development SR Khetani, SN Bhatia Nature biotechnology 26 (1), 120-126, 2008 | 1423 | 2008 |
Pluripotent stem cell-derived hepatocyte-like cells RE Schwartz, HE Fleming, SR Khetani, SN Bhatia Biotechnology advances 32 (2), 504-513, 2014 | 326 | 2014 |
In Vitro Zonation and Toxicity in a Hepatocyte Bioreactor JW Allen, SR Khetani, SN Bhatia Toxicological sciences 84 (1), 110-119, 2005 | 304 | 2005 |
Real-time imaging of hepatitis C virus infection using a fluorescent cell-based reporter system CT Jones, MT Catanese, LMJ Law, SR Khetani, AJ Syder, A Ploss, TS Oh, ... Nature biotechnology 28 (2), 167-171, 2010 | 288 | 2010 |
Quantum dots to monitor RNAi delivery and improve gene silencing AA Chen, AM Derfus, SR Khetani, SN Bhatia Nucleic acids research 33 (22), e190-e190, 2005 | 238 | 2005 |
Persistent hepatitis C virus infection in microscale primary human hepatocyte cultures A Ploss, SR Khetani, CT Jones, AJ Syder, K Trehan, VA Gaysinskaya, ... Proceedings of the National Academy of Sciences 107 (7), 3141-3145, 2010 | 235 | 2010 |
Microenvironmental regulation of the sinusoidal endothelial cell phenotype in vitro S March, EE Hui, GH Underhill, S Khetani, SN Bhatia Hepatology 50 (3), 920-928, 2009 | 224 | 2009 |
Superhydrophobic coatings with edible materials W Wang, K Lockwood, LM Boyd, MD Davidson, S Movafaghi, H Vahabi, ... ACS applied materials & interfaces 8 (29), 18664-18668, 2016 | 223 | 2016 |
Use of micropatterned cocultures to detect compounds that cause drug-induced liver injury in humans SR Khetani, C Kanchagar, O Ukairo, S Krzyzewski, A Moore, J Shi, ... toxicological sciences 132 (1), 107-117, 2013 | 221 | 2013 |
Enhancing the functional maturity of induced pluripotent stem cell–derived human hepatocytes by controlled presentation of cell–cell interactions in vitro DR Berger, BR Ware, MD Davidson, SR Allsup, SR Khetani Hepatology 61 (4), 1370-1381, 2015 | 214* | 2015 |
Prediction of drug-induced liver injury in micropatterned co-cultures containing iPSC-derived human hepatocytes BR Ware, DR Berger, SR Khetani Toxicological sciences 145 (2), 252-262, 2015 | 201 | 2015 |
Engineering tissues for in vitro applications SR Khetani, SN Bhatia Current opinion in biotechnology 17 (5), 524-531, 2006 | 181 | 2006 |
Meeting the challenge of predicting hepatic clearance of compounds slowly metabolized by cytochrome P450 using a novel hepatocyte model, HepatoPac TS Chan, H Yu, A Moore, SR Khetani, D Tweedie Drug metabolism and disposition 47 (1), 58-66, 2019 | 175 | 2019 |
Micropatterned coculture of primary human hepatocytes and supportive cells for the study of hepatotropic pathogens S March, V Ramanan, K Trehan, S Ng, A Galstian, N Gural, MA Scull, ... Nature protocols 10 (12), 2027-2053, 2015 | 174 | 2015 |
Exploring interactions between rat hepatocytes and nonparenchymal cells using gene expression profiling SR Khetani, G Szulgit, JA Del Rio, C Barlow, SN Bhatia Hepatology 40 (3), 545-554, 2004 | 169 | 2004 |
Bioengineered liver models for drug testing and cell differentiation studies GH Underhill, SR Khetani Cellular and molecular gastroenterology and hepatology 5 (3), 426-439. e1, 2018 | 167 | 2018 |
Assessment of a micropatterned hepatocyte coculture system to generate major human excretory and circulating drug metabolites WWW Wang, SR Khetani, S Krzyzewski, DB Duignan, RS Obach Drug metabolism and disposition 38 (10), 1900-1905, 2010 | 166 | 2010 |
Establishment of a hepatocyte-kupffer cell coculture model for assessment of proinflammatory cytokine effects on metabolizing enzymes and drug transporters TV Nguyen, O Ukairo, SR Khetani, M McVay, C Kanchagar, W Seghezzi, ... Drug metabolism and disposition 43 (5), 774-785, 2015 | 146 | 2015 |
Microengineered liver tissues for drug testing SR Khetani, DR Berger, KR Ballinger, MD Davidson, C Lin, BR Ware Journal of laboratory automation 20 (3), 216-250, 2015 | 133 | 2015 |
Hepatitis C virus infection induces autocrine interferon signaling by human liver endothelial cells and release of exosomes, which inhibits viral replication S Giugliano, M Kriss, L Golden-Mason, E Dobrinskikh, AEL Stone, ... Gastroenterology 148 (2), 392-402. e13, 2015 | 116 | 2015 |