Intracellular calcium leak in heart failure and atrial fibrillation: a unifying mechanism and therapeutic target H Dridi, A Kushnir, R Zalk, Q Yuan, Z Melville, AR Marks Nature Reviews Cardiology 17 (11), 732-747, 2020 | 172 | 2020 |
Alzheimer's‐like signaling in brains of COVID‐19 patients S Reiken, L Sittenfeld, H Dridi, Y Liu, X Liu, AR Marks Alzheimer's & Dementia 18 (5), 955-965, 2022 | 171 | 2022 |
Leaky ryanodine receptors contribute to diaphragmatic weakness during mechanical ventilation S Matecki, H Dridi, B Jung, N Saint, SR Reiken, V Scheuermann, ... Proceedings of the National Academy of Sciences 113 (32), 9069-9074, 2016 | 98 | 2016 |
ER stress disturbs SR/ER-mitochondria Ca2+ transfer: Implications in Duchenne muscular dystrophy M Pauly, C Angebault-Prouteau, H Dridi, C Notarnicola, V Scheuermann, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1863 (9 …, 2017 | 56 | 2017 |
Structural analyses of human ryanodine receptor type 2 channels reveal the mechanisms for sudden cardiac death and treatment MC Miotto, G Weninger, H Dridi, Q Yuan, Y Liu, A Wronska, Z Melville, ... Science Advances 8 (29), eabo1272, 2022 | 40 | 2022 |
Mitochondrial oxidative stress induces leaky ryanodine receptor during mechanical ventilation H Dridi, M Yehya, R Barsotti, S Reiken, C Angebault, B Jung, S Jaber, ... Free Radical Biology and Medicine 146, 383-391, 2020 | 38 | 2020 |
A drug and ATP binding site in type 1 ryanodine receptor Z Melville, H Dridi, Q Yuan, S Reiken, A Wronska, Y Liu, OB Clarke, ... Structure 30 (7), 1025-1034. e4, 2022 | 37 | 2022 |
Role of defective calcium regulation in cardiorespiratory dysfunction in Huntington’s disease H Dridi, X Liu, Q Yuan, S Reiken, M Yehya, L Sittenfeld, P Apostolou, ... JCI insight 5 (19), 2020 | 37 | 2020 |
Acute RyR1 Ca2+ leak enhances NADH-linked mitochondrial respiratory capacity N Zanou, H Dridi, S Reiken, T Imamura de Lima, C Donnelly, U De Marchi, ... Nature Communications 12 (1), 7219, 2021 | 34 | 2021 |
Heart failure-induced cognitive dysfunction is mediated by intracellular Ca2+ leak through ryanodine receptor type 2 H Dridi, Y Liu, S Reiken, X Liu, EK Argyrousi, Q Yuan, MC Miotto, ... Nature Neuroscience 26 (8), 1365-1378, 2023 | 29 | 2023 |
Attenuating persistent sodium current–induced atrial myopathy and fibrillation by preventing mitochondrial oxidative stress UMR Avula, H Dridi, B Chen, Q Yuan, AN Katchman, SR Reiken, ... JCI insight 6 (23), 2021 | 28 | 2021 |
Ryanodine receptor remodeling in cardiomyopathy and muscular dystrophy caused by lamin A/C gene mutation H Dridi, W Wu, SR Reiken, RM Ofer, Y Liu, Q Yuan, L Sittenfeld, ... Human Molecular Genetics 29 (24), 3919-3934, 2020 | 22 | 2020 |
IP3 receptor orchestrates maladaptive vascular responses in heart failure H Dridi, G Santulli, J Gambardella, SS Jankauskas, Q Yuan, J Yang, ... The Journal of clinical investigation 132 (4), 2022 | 19 | 2022 |
Mitochondrial calcium overload plays a causal role in oxidative stress in the failing heart H Dridi, G Santulli, L Bahlouli, MC Miotto, G Weninger, AR Marks Biomolecules 13 (9), 1409, 2023 | 14 | 2023 |
RyR1-related myopathy mutations in ATP and calcium binding sites impair channel regulation Q Yuan, H Dridi, OB Clarke, S Reiken, Z Melville, A Wronska, A Kushnir, ... Acta neuropathologica communications 9, 1-15, 2021 | 12 | 2021 |
Late ventilator-induced diaphragmatic dysfunction after extubation H Dridi, B Jung, M Yehya, A Daurat, S Reiken, J Moreau, AR Marks, ... Critical Care Medicine 48 (12), e1300-e1305, 2020 | 12 | 2020 |
Role of oxidation of excitation-contraction coupling machinery in age-dependent loss of muscle function in Caenorhabditis elegans H Dridi, F Forrester, A Umanskaya, W Xie, S Reiken, A Lacampagne, ... Elife 11, e75529, 2022 | 10 | 2022 |
Alzheimer’s-like remodeling of neuronal ryanodine receptor in COVID-19 S Reiken, H Dridi, L Sittenfeld, X Liu, AR Marks BioRxiv, 2021.02. 18.431811, 2021 | 9 | 2021 |
Effect of pyridostigmine on in vivo and in vitro respiratory muscle of mdx mice GCS Amancio, A Grabe-Guimarães, D Haikel, J Moreau, NMS Barcellos, ... Respiratory Physiology & Neurobiology 243, 107-114, 2017 | 8 | 2017 |
Intracellular calcium leak: a unifying mechanism and therapeutic target for heart failure and atrial fibrillation H Dridi, A Kushnir, R Zalk, Q Yuan, Z Melville, AR Marks Nature reviews. Cardiology 17 (11), 732, 2020 | 5 | 2020 |