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Haikel Dridi
Haikel Dridi
Verified email at cumc.columbia.edu
Title
Cited by
Cited by
Year
Intracellular calcium leak in heart failure and atrial fibrillation: a unifying mechanism and therapeutic target
H Dridi, A Kushnir, R Zalk, Q Yuan, Z Melville, AR Marks
Nature Reviews Cardiology 17 (11), 732-747, 2020
1722020
Alzheimer's‐like signaling in brains of COVID‐19 patients
S Reiken, L Sittenfeld, H Dridi, Y Liu, X Liu, AR Marks
Alzheimer's & Dementia 18 (5), 955-965, 2022
1712022
Leaky ryanodine receptors contribute to diaphragmatic weakness during mechanical ventilation
S Matecki, H Dridi, B Jung, N Saint, SR Reiken, V Scheuermann, ...
Proceedings of the National Academy of Sciences 113 (32), 9069-9074, 2016
982016
ER stress disturbs SR/ER-mitochondria Ca2+ transfer: Implications in Duchenne muscular dystrophy
M Pauly, C Angebault-Prouteau, H Dridi, C Notarnicola, V Scheuermann, ...
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1863 (9 …, 2017
562017
Structural analyses of human ryanodine receptor type 2 channels reveal the mechanisms for sudden cardiac death and treatment
MC Miotto, G Weninger, H Dridi, Q Yuan, Y Liu, A Wronska, Z Melville, ...
Science Advances 8 (29), eabo1272, 2022
402022
Mitochondrial oxidative stress induces leaky ryanodine receptor during mechanical ventilation
H Dridi, M Yehya, R Barsotti, S Reiken, C Angebault, B Jung, S Jaber, ...
Free Radical Biology and Medicine 146, 383-391, 2020
382020
A drug and ATP binding site in type 1 ryanodine receptor
Z Melville, H Dridi, Q Yuan, S Reiken, A Wronska, Y Liu, OB Clarke, ...
Structure 30 (7), 1025-1034. e4, 2022
372022
Role of defective calcium regulation in cardiorespiratory dysfunction in Huntington’s disease
H Dridi, X Liu, Q Yuan, S Reiken, M Yehya, L Sittenfeld, P Apostolou, ...
JCI insight 5 (19), 2020
372020
Acute RyR1 Ca2+ leak enhances NADH-linked mitochondrial respiratory capacity
N Zanou, H Dridi, S Reiken, T Imamura de Lima, C Donnelly, U De Marchi, ...
Nature Communications 12 (1), 7219, 2021
342021
Heart failure-induced cognitive dysfunction is mediated by intracellular Ca2+ leak through ryanodine receptor type 2
H Dridi, Y Liu, S Reiken, X Liu, EK Argyrousi, Q Yuan, MC Miotto, ...
Nature Neuroscience 26 (8), 1365-1378, 2023
292023
Attenuating persistent sodium current–induced atrial myopathy and fibrillation by preventing mitochondrial oxidative stress
UMR Avula, H Dridi, B Chen, Q Yuan, AN Katchman, SR Reiken, ...
JCI insight 6 (23), 2021
282021
Ryanodine receptor remodeling in cardiomyopathy and muscular dystrophy caused by lamin A/C gene mutation
H Dridi, W Wu, SR Reiken, RM Ofer, Y Liu, Q Yuan, L Sittenfeld, ...
Human Molecular Genetics 29 (24), 3919-3934, 2020
222020
IP3 receptor orchestrates maladaptive vascular responses in heart failure
H Dridi, G Santulli, J Gambardella, SS Jankauskas, Q Yuan, J Yang, ...
The Journal of clinical investigation 132 (4), 2022
192022
Mitochondrial calcium overload plays a causal role in oxidative stress in the failing heart
H Dridi, G Santulli, L Bahlouli, MC Miotto, G Weninger, AR Marks
Biomolecules 13 (9), 1409, 2023
142023
RyR1-related myopathy mutations in ATP and calcium binding sites impair channel regulation
Q Yuan, H Dridi, OB Clarke, S Reiken, Z Melville, A Wronska, A Kushnir, ...
Acta neuropathologica communications 9, 1-15, 2021
122021
Late ventilator-induced diaphragmatic dysfunction after extubation
H Dridi, B Jung, M Yehya, A Daurat, S Reiken, J Moreau, AR Marks, ...
Critical Care Medicine 48 (12), e1300-e1305, 2020
122020
Role of oxidation of excitation-contraction coupling machinery in age-dependent loss of muscle function in Caenorhabditis elegans
H Dridi, F Forrester, A Umanskaya, W Xie, S Reiken, A Lacampagne, ...
Elife 11, e75529, 2022
102022
Alzheimer’s-like remodeling of neuronal ryanodine receptor in COVID-19
S Reiken, H Dridi, L Sittenfeld, X Liu, AR Marks
BioRxiv, 2021.02. 18.431811, 2021
92021
Effect of pyridostigmine on in vivo and in vitro respiratory muscle of mdx mice
GCS Amancio, A Grabe-Guimarães, D Haikel, J Moreau, NMS Barcellos, ...
Respiratory Physiology & Neurobiology 243, 107-114, 2017
82017
Intracellular calcium leak: a unifying mechanism and therapeutic target for heart failure and atrial fibrillation
H Dridi, A Kushnir, R Zalk, Q Yuan, Z Melville, AR Marks
Nature reviews. Cardiology 17 (11), 732, 2020
52020
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Articles 1–20