| Protective efficacy and safety of three antimalarial regimens for the prevention of malaria in young Ugandan children: a randomized controlled trial V Bigira, J Kapisi, TD Clark, S Kinara, F Mwangwa, MK Muhindo, ... PLoS medicine 11 (8), e1001689, 2014 | 119 | 2014 |
| Pharmacokinetics and model-based dosing to optimize fludarabine therapy in pediatric hematopoietic cell transplant recipients V Ivaturi, CC Dvorak, D Chan, T Liu, MJ Cowan, J Wahlstrom, M Stricherz, ... Biology of Blood and Marrow Transplantation 23 (10), 1701-1713, 2017 | 61 | 2017 |
| Concomitant efavirenz reduces pharmacokinetic exposure to the antimalarial drug artemether–lumefantrine in healthy volunteers L Huang, S Parikh, PJ Rosenthal, P Lizak, F Marzan, G Dorsey, D Havlir, ... JAIDS Journal of Acquired Immune Deficiency Syndromes 61 (3), 310-316, 2012 | 59 | 2012 |
| In vitro metabolism of piperaquine is primarily mediated by CYP3A4 TMN Lee, L Huang, MK Johnson, P Lizak, D Kroetz, F Aweeka, S Parikh Xenobiotica 42 (11), 1088-1095, 2012 | 57 | 2012 |
| Role of heme-protein covalent bonds in mammalian peroxidases: protection of the heme by a single engineered heme-protein link in horseradish peroxidase L Huang, G Wojciechowski, PRO de Montellano Journal of Biological Chemistry 281 (28), 18983-18988, 2006 | 57 | 2006 |
| Diversity-oriented chemical modification of heparin: Identification of charge-reduced N-acyl heparin derivatives having increased selectivity for heparin-binding proteins L Huang, RJ Kerns Bioorganic & medicinal chemistry 14 (7), 2300-2313, 2006 | 49 | 2006 |
| Antiretroviral therapy with efavirenz accentuates pregnancy‐associated reduction of dihydroartemisinin‐piperaquine exposure during malaria chemoprevention R Kajubi, L Huang, P Jagannathan, N Chamankhah, M Were, T Ruel, ... Clinical Pharmacology & Therapeutics 102 (3), 520-528, 2017 | 47 | 2017 |
| Development and validation of a hydrophilic interaction liquid chromatography–tandem mass spectrometry method for determination of isoniazid in human plasma L Huang, F Marzan, AL Jayewardene, PS Lizak, X Li, FT Aweeka Journal of Chromatography B 877 (3), 285-290, 2009 | 47 | 2009 |
| Prosthetic heme modification during halide ion oxidation. Demonstration of chloride oxidation by horseradish peroxidase L Huang, G Wojciechowski, PR Ortiz de Montellano Journal of the American Chemical Society 127 (15), 5345-5353, 2005 | 47 | 2005 |
| Oxidation of carboxylic acids by horseradish peroxidase results in prosthetic heme modification and inactivation L Huang, C Colas, PR Ortiz de Montellano Journal of the American Chemical Society 126 (40), 12865-12873, 2004 | 46 | 2004 |
| Development and validation of a high-performance liquid chromatography/tandem mass spectrometry method for the determination of artemether and its active metabolite … L Huang, AL Jayewardene, X Li, F Marzan, PS Lizak, FT Aweeka Journal of pharmaceutical and biomedical analysis 50 (5), 959-965, 2009 | 45 | 2009 |
| Artemether-lumefantrine pharmacokinetics and clinical response are minimally altered in pregnant Ugandan women treated for uncomplicated falciparum malaria MM Nyunt, VK Nguyen, R Kajubi, L Huang, J Ssebuliba, S Kiconco, ... Antimicrobial agents and chemotherapy 60 (3), 1274-1282, 2016 | 39 | 2016 |
| Determination of lumefantrine in small-volume human plasma by LC–MS/MS: using a deuterated lumefantrine to overcome matrix effect and ionization saturation L Huang, X Li, F Marzan, PS Lizak, FT Aweeka Bioanalysis 4 (2), 157-166, 2012 | 38 | 2012 |
| Spatiotemporal pharmacodynamics of meropenem- and tobramycin-treated Pseudomonas aeruginosa biofilms J Haagensen, D Verotta, L Huang, J Engel, AM Spormann, K Yang Journal of Antimicrobial Chemotherapy 72 (12), 3357-3365, 2017 | 37 | 2017 |
| Antiretroviral choice for HIV impacts antimalarial exposure and treatment outcomes in Ugandan children S Parikh, R Kajubi, L Huang, J Ssebuliba, S Kiconco, Q Gao, F Li, M Were, ... Reviews of Infectious Diseases 63 (3), 414-422, 2016 | 37 | 2016 |
| Efficacy and safety of three regimens for the prevention of malaria in young HIV-exposed Ugandan children: a randomized controlled trial MR Kamya, J Kapisi, V Bigira, TD Clark, S Kinara, F Mwangwa, ... Aids 28 (18), 2701-2709, 2014 | 37 | 2014 |
| Determination of artemether and dihydroartemisinin in human plasma with a new hydrogen peroxide stabilization method L Huang, A Olson, D Gingrich, FT Aweeka Bioanalysis 5 (12), 1501-1506, 2013 | 36 | 2013 |
| Determination of the antimalarial drug piperaquine in small volume pediatric plasma samples by LC–MS/MS LL Kjellin, G Dorsey, PJ Rosenthal, F Aweeka, L Huang Bioanalysis 6 (23), 3081-3089, 2014 | 34 | 2014 |
| Intermittent preventive treatment for malaria in pregnancy: optimization of target concentrations of dihydroartemisinin-piperaquine RM Savic, P Jagannathan, R Kajubi, L Huang, N Zhang, M Were, ... Clinical Infectious Diseases 67 (7), 1079-1088, 2018 | 33 | 2018 |
| Autocatalytic Modification of the Prosthetic Heme of Horseradish but Not Lactoperoxidase by Thiocyanate Oxidation Products. A Role for Heme− Protein Covalent Cross-Linking G Wojciechowski, L Huang, PR Ortiz de Montellano Journal of the American Chemical Society 127 (45), 15871-15879, 2005 | 33 | 2005 |
