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Graham M Hughes
Graham M Hughes
Verified email at ucd.ie
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Year
Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms
DE Gordon, J Hiatt, M Bouhaddou, VV Rezelj, S Ulferts, H Braberg, ...
Science 370 (6521), eabe9403, 2020
6842020
Broad host range of SARS-CoV-2 predicted by comparative and structural analysis of ACE2 in vertebrates
J Damas, GM Hughes, KC Keough, CA Painter, NS Persky, M Corbo, ...
Proceedings of the National Academy of Sciences 117 (36), 22311-22322, 2020
6822020
Six reference-quality genomes reveal evolution of bat adaptations
D Jebb, Z Huang, M Pippel, GM Hughes, K Lavrichenko, P Devanna, ...
Nature 583 (7817), 578-584, 2020
3052020
Bat biology, genomes, and the Bat1K project: to generate chromosome-level genomes for all living bat species
EC Teeling, SC Vernes, LM Dávalos, DA Ray, MTP Gilbert, E Myers, ...
Annual review of animal biosciences 6 (1), 23-46, 2018
2412018
Genome-wide signatures of complex introgression and adaptive evolution in the big cats
HV Figueiró, G Li, FJ Trindade, J Assis, F Pais, G Fernandes, SHD Santos, ...
Science Advances 3 (7), e1700299, 2017
1802017
Growing old, yet staying young: the role of telomeres in bats’ exceptional longevity
NM Foley, GM Hughes, Z Huang, M Clarke, D Jebb, CV Whelan, EJ Petit, ...
Science Advances 4 (2), eaao0926, 2018
1742018
Evolutionary constraint and innovation across hundreds of placental mammals
MJ Christmas, IM Kaplow, DP Genereux, MX Dong, GM Hughes, X Li, ...
Science 380 (6643), eabn3943, 2023
1542023
The birth and death of olfactory receptor gene families in mammalian niche adaptation
GM Hughes, ESM Boston, JA Finarelli, WJ Murphy, DG Higgins, ...
Molecular biology and evolution 35 (6), 1390-1406, 2018
1152018
Integrating gene annotation with orthology inference at scale
BM Kirilenko, C Munegowda, E Osipova, D Jebb, V Sharma, M Blumer, ...
Science 380 (6643), eabn3107, 2023
872023
A genomic timescale for placental mammal evolution
NM Foley, VC Mason, AJ Harris, KR Bredemeyer, J Damas, HA Lewin, ...
Science 380 (6643), eabl8189, 2023
822023
A novel method of microsatellite genotyping-by-sequencing using individual combinatorial barcoding
S Vartia, JL Villanueva-Cañas, J Finarelli, ED Farrell, PC Collins, ...
Royal Society Open Science 3 (1), 150565, 2016
822016
Leveraging base-pair mammalian constraint to understand genetic variation and human disease
PF Sullivan, JRS Meadows, S Gazal, BDN Phan, X Li, DP Genereux, ...
Science 380 (6643), eabn2937, 2023
732023
A potent anti-inflammatory response in bat macrophages may be linked to extended longevity and viral tolerance
J Kacprzyk, GM Hughes, EM Palsson-McDermott, SR Quinn, ...
Acta chiropterologica 19 (2), 219-228, 2017
732017
Genome analysis of the metabolically versatile Pseudomonas umsongensis GO16: the genetic basis for PET monomer upcycling into polyhydroxyalkanoates
T Narancic, M Salvador, GM Hughes, N Beagan, U Abdulmutalib, ...
Microbial biotechnology 14 (6), 2463-2480, 2021
682021
Large‐scale genome sampling reveals unique immunity and metabolic adaptations in bats
DD Moreno Santillán, TM Lama, YT Gutierrez Guerrero, AM Brown, ...
Molecular ecology 30 (23), 6449-6467, 2021
662021
Three-dimensional genome rewiring in loci with human accelerated regions
KC Keough, S Whalen, F Inoue, PF Przytycki, T Fair, C Deng, M Steyert, ...
Science 380 (6643), eabm1696, 2023
592023
Insights into mammalian TE diversity through the curation of 248 genome assemblies
AB Osmanski, NS Paulat, J Korstian, JR Grimshaw, M Halsey, ...
Science 380 (6643), eabn1430, 2023
572023
Drivers of longitudinal telomere dynamics in a long‐lived bat species, Myotis myotis
NM Foley, EJ Petit, T Brazier, JA Finarelli, GM Hughes, F Touzalin, ...
Molecular Ecology 29 (16), 2963-2977, 2020
562020
Mammalian evolution of human cis-regulatory elements and transcription factor binding sites
G Andrews, K Fan, HE Pratt, N Phalke, Zoonomia Consortium §, ...
Science 380 (6643), eabn7930, 2023
522023
Relating enhancer genetic variation across mammals to complex phenotypes using machine learning
IM Kaplow, AJ Lawler, DE Schäffer, C Srinivasan, HH Sestili, ME Wirthlin, ...
Science 380 (6643), eabm7993, 2023
522023
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