Targeting diverse protein–protein interaction interfaces with α/β-peptides derived from the Z-domain scaffold JW Checco, DF Kreitler, NC Thomas, DG Belair, NJ Rettko, WL Murphy, ... Proceedings of the National Academy of Sciences 112 (15), 4552-4557, 2015 | 121 | 2015 |
The structural basis of N-acyl-α-amino-β-lactone formation catalyzed by a nonribosomal peptide synthetase DF Kreitler, EM Gemmell, JE Schaffer, TA Wencewicz, AM Gulick Nature communications 10 (1), 3432, 2019 | 66 | 2019 |
Effects of single α-to-β residue replacements on structure and stability in a small protein: insights from quasiracemic crystallization DF Kreitler, DE Mortenson, KT Forest, SH Gellman Journal of the American Chemical Society 138 (20), 6498-6505, 2016 | 50 | 2016 |
The nitro group as a masked electrophile in covalent enzyme inhibition S Ray, DF Kreitler, AM Gulick, AS Murkin ACS chemical biology 13 (6), 1470-1473, 2018 | 40 | 2018 |
High-resolution structures of a heterochiral coiled coil DE Mortenson, JD Steinkruger, DF Kreitler, DV Perroni, GP Sorenson, ... Proceedings of the National Academy of Sciences 112 (43), 13144-13149, 2015 | 40 | 2015 |
Use of a stereochemical strategy to probe the mechanism of phenol-soluble modulin α3 toxicity Z Yao, BP Cary, CA Bingman, C Wang, DF Kreitler, KA Satyshur, ... Journal of the American Chemical Society 141 (19), 7660-7664, 2019 | 34 | 2019 |
Evidence for phenylalanine zipper-mediated dimerization in the X-ray crystal structure of a magainin 2 analogue Z Hayouka, DE Mortenson, DF Kreitler, B Weisblum, KT Forest, ... Journal of the American Chemical Society 135 (42), 15738-15741, 2013 | 32 | 2013 |
Biosynthesis, Mechanism of Action, and Inhibition of the Enterotoxin Tilimycin Produced by the Opportunistic Pathogen Klebsiella oxytoca EM Alexander, DF Kreitler, V Guidolin, AK Hurben, E Drake, PW Villalta, ... ACS infectious diseases 6 (7), 1976-1997, 2020 | 31 | 2020 |
A hendecad motif is preferred for heterochiral coiled-coil formation DF Kreitler, Z Yao, JD Steinkruger, DE Mortenson, L Huang, R Mittal, ... Journal of the American Chemical Society 141 (4), 1583-1592, 2019 | 30 | 2019 |
Hepatitis C virus NS3/4A inhibitors and other drug-like compounds as covalent binders of SARS-CoV-2 main protease B Andi, D Kumaran, DF Kreitler, AS Soares, J Keereetaweep, J Jakoncic, ... Scientific reports 12 (1), 12197, 2022 | 29 | 2022 |
Dual inhibition of human parainfluenza type 3 and respiratory syncytial virus infectivity with a single agent VK Outlaw, S Bottom-Tanzer, DF Kreitler, SH Gellman, M Porotto, ... Journal of the American Chemical Society 141 (32), 12648-12656, 2019 | 26 | 2019 |
Retention of native quaternary structure in racemic melittin crystals KW Kurgan, AF Kleman, CA Bingman, DF Kreitler, B Weisblum, KT Forest, ... Journal of the American Chemical Society 141 (19), 7704-7708, 2019 | 25 | 2019 |
Engineering protease-resistant peptides to inhibit human parainfluenza viral respiratory infection VK Outlaw, RW Cheloha, EM Jurgens, FT Bovier, Y Zhu, DF Kreitler, ... Journal of the American Chemical Society 143 (15), 5958-5966, 2021 | 23 | 2021 |
Evaluation of β‐amino acid replacements in protein loops: effects on conformational stability and structure DE Mortenson, DF Kreitler, NC Thomas, IA Guzei, SH Gellman, KT Forest ChemBioChem 19 (6), 604-612, 2018 | 21 | 2018 |
AMX–the highly automated macromolecular crystallography (17-ID-1) beamline at the NSLS-II DK Schneider, AS Soares, EO Lazo, DF Kreitler, K Qian, MR Fuchs, ... Journal of Synchrotron Radiation 29 (6), 1480-1494, 2022 | 15 | 2022 |
Effects of single α-to-β residue replacements on recognition of an extended segment in a viral fusion protein VK Outlaw, DF Kreitler, D Stelitano, M Porotto, A Moscona, SH Gellman ACS infectious diseases 6 (8), 2017-2022, 2020 | 11 | 2020 |
Evidence for small-molecule-mediated loop stabilization in the structure of the isolated Pin1 WW domain DE Mortenson, DF Kreitler, HG Yun, SH Gellman, KT Forest Acta Crystallographica Section D: Biological Crystallography 69 (12), 2506-2512, 2013 | 10 | 2013 |
A hemoprotein with a zinc-mirror heme site ties heme availability to carbon metabolism in cyanobacteria N Grosjean, EF Yee, D Kumaran, K Chopra, M Abernathy, S Biswas, ... Nature communications 15 (1), 3167, 2024 | 8 | 2024 |
A hydrophobic domain within the small capsid protein of Kaposi’s sarcoma-associated herpesvirus is required for assembly CM Capuano, P Grzesik, D Kreitler, EN Pryce, KV Desai, G Coombs, ... Journal of General Virology 95 (8), 1755-1769, 2014 | 8 | 2014 |
The ribosomal RNA processing 1B: protein phosphatase 1 holoenzyme reveals non-canonical PP1 interaction motifs G Srivastava, R Bajaj, GS Kumar, A Gaudreau-Lapierre, H Nicolas, ... Cell reports 41 (9), 2022 | 7 | 2022 |