| An Update on the Structure of hERG A Butler, MV Helliwell, Y Zhang, JC Hancox, CE Dempsey Frontiers in pharmacology 10, 1572, 2020 | 82 | 2020 |
| Action potential clamp characterization of the S631A hERG mutation associated with short QT syndrome A Butler, Y Zhang, AG Stuart, CE Dempsey, JC Hancox Physiological reports 6 (17), e13845, 2018 | 17 | 2018 |
| Pro-arrhythmic effects of gain-of-function potassium channel mutations in the short QT syndrome JC Hancox, CY Du, A Butler, Y Zhang, CE Dempsey, SC Harmer, ... Philosophical Transactions of the Royal Society B 378 (1879), 20220165, 2023 | 16 | 2023 |
| Functional and pharmacological characterization of an S5 domain hERG mutation associated with short QT syndrome A Butler, Y Zhang, AG Stuart, CE Dempsey, JC Hancox Heliyon 5 (4), 2019 | 15 | 2019 |
| The short QT syndrome JC Hancox, MJ McPate, A El Harchi, AS Butler, Y Zhang, DG Whittaker, ... Heart Rate and Rhythm: Molecular Basis, Pharmacological Modulation and …, 2023 | 8 | 2023 |
| The macrolide drug erythromycin does not protect the hERG channel from inhibition by thioridazine and terfenadine A El Harchi, AS Butler, Y Zhang, CE Dempsey, JC Hancox Physiological Reports 8 (5), e14385, 2020 | 7 | 2020 |
| Preferential formation of human heteromeric SK2: SK3 channels limits homomeric SK channel assembly and function AS Butler, JC Hancox, NV Marrion Journal of Biological Chemistry 299 (1), 2023 | 5 | 2023 |
| Total and Free Blood and Plasma Concentration Changes in Pregnancy for Medicines Highly Bound to Plasma Proteins: Application of Physiologically Based Pharmacokinetic Modelling … P Coppola, A Butler, S Cole, E Kerwash Pharmaceutics 15 (10), 2455, 2023 | 4 | 2023 |
| In situ monolayer patch clamp of acutely stimulated human iPSC-derived cardiomyocytes promotes consistent electrophysiological responses to SK channel inhibition AS Butler, R Ascione, NV Marrion, SC Harmer, JC Hancox Scientific Reports 14 (1), 3185, 2024 | 3 | 2024 |
| Addressing health equity for breastfeeding women: primaquine for Plasmodium vivax radical cure N Abla, AC Marrast, E Jambert, N Richardson, S Duparc, L Almond, ... Malaria Journal 23 (1), 287, 2024 | 1 | 2024 |
| Exploring the Feasibility of a Bracketing Approach Utilizing Modeling for Development of Long-Acting Injectables for Regulatory Approval—A Case Study Using Levonorgestrel S Cole, H Pertinez, AS Butler, E Kerwash, S Bhat, E El-Khateeb, A Owen Pharmaceuticals 17 (12), 1640, 2024 | | 2024 |
| Evaluation of mathematical models for predicting medicine distribution into breastmilk-considering biological heterogeneity S Heo, AS Butler, M Stamouli Simoncioni, S Moult, M Malamatari, ... Frontiers in Pharmacology 15, 1507551, 2024 | | 2024 |
| Investigation of a fully mechanistic physiologically based pharmacokinetics model of absorption to support predictions of milk concentrations in breastfeeding women and the … S Cole, M Malamatari, A Butler, M Arshad, E Kerwash CPT: Pharmacometrics & Systems Pharmacology 13 (11), 1990-2001, 2024 | | 2024 |
| Regulatory Assessment of Casgevy for the Treatment of Transfusion-Dependent β-Thalassemia and Sickle Cell Disease with Recurrent Vaso-Occlusive Crises E Kerwash, M Sajic, KR Rantell, JW McBlane, JD Johnston, ... Current Issues in Molecular Biology 46 (8), 8209-8225, 2024 | | 2024 |
| The entrainment of action potential duration and contraction amplitude by recapitulation of respiratory sinus arrhythmia in isolated cardiac myocytes A Carpenter, LMK Pannell, ED Fowler, AS Butler, JFR Paton, JC Hancox, ... Europace 26 (Supplement_1), euae102. 619, 2024 | | 2024 |
| A single coiled‐coil domain mutation in hIKCa channel subunits disrupts preferential formation of heteromeric hSK1: hIKCa channels JN Charlick, D Bozadzhieva, AS Butler, KA Wilkinson, NV Marrion European Journal of Neuroscience 59 (1), 3-16, 2024 | | 2024 |
| Palmitoylation regulates the magnitude of HCN4-mediated currents in mammalian cells SD Congreve, A Main, AS Butler, X Gao, E Brown, C Du, SC Choisy, ... Frontiers in Physiology 14, 1163339, 2023 | | 2023 |
| The Short QT Syndrome 26 JC Hancox, MJ McPate, A El Harchi, AS Butler, Y Zhang, DG Whittaker, ... Heart Rate and Rhythm, 517, 2023 | | 2023 |
| Development of IPSC-derived Human Cardiac Myocytes for the Targeting of SK Channels AS Butler University of Bristol, 2023 | | 2023 |
| Recapitulation of heart rate variability suppresses alternans in guinea pig ventricular myocytes A Carpenter, AS Butler, LMK Pannell, JFR Paton, JC Hancox, AF James ACTA PHYSIOLOGICA 236, 601-601, 2022 | | 2022 |
