Ca2+/Calmodulin–Dependent Protein Kinase Modulates Cardiac Ryanodine Receptor Phosphorylation and Sarcoplasmic Reticulum Ca2+ Leak in Heart Failure X Ai, JW Curran, TR Shannon, DM Bers, SM Pogwizd Circulation research 97 (12), 1314-1322, 2005 | 877 | 2005 |
Role of RyR2 phosphorylation at S2814 during heart failure progression JL Respress, RJ Van Oort, N Li, N Rolim, SS Dixit, A Dealmeida, N Voigt, ... Circulation research 110 (11), 1474-1483, 2012 | 265 | 2012 |
Connexin 43 downregulation and dephosphorylation in nonischemic heart failure is associated with enhanced colocalized protein phosphatase type 2A X Ai, SM Pogwizd Circulation research 96 (1), 54-63, 2005 | 260 | 2005 |
Expression and phosphorylation of the Na-pump regulatory subunit phospholemman in heart failure J Bossuyt, X Ai, JR Moorman, SM Pogwizd, DM Bers Circulation research 97 (6), 558-565, 2005 | 139 | 2005 |
Arrhythmogenic Effects of β2-Adrenergic Stimulation in the Failing Heart Are Attributable to Enhanced Sarcoplasmic Reticulum Ca Load J DeSantiago, X Ai, M Islam, G Acuna, MT Ziolo, DM Bers, SM Pogwizd Circulation research 102 (11), 1389-1397, 2008 | 138 | 2008 |
Role of stress kinase JNK in binge alcohol-evoked atrial arrhythmia J Yan, JK Thomson, W Zhao, X Gao, F Huang, B Chen, Q Liang, LS Song, ... Journal of the American College of Cardiology 71 (13), 1459-1470, 2018 | 97 | 2018 |
Connexin40 abnormalities and atrial fibrillation in the human heart J Gemel, AE Levy, AR Simon, KB Bennett, X Ai, S Akhter, EC Beyer Journal of molecular and cellular cardiology 76, 159-168, 2014 | 81 | 2014 |
Ion channel and structural remodeling in obesity-mediated atrial fibrillation MD McCauley, L Hong, A Sridhar, A Menon, S Perike, M Zhang, ... Circulation: Arrhythmia and Electrophysiology 13 (8), e008296, 2020 | 80 | 2020 |
Stress signaling JNK2 crosstalk with CaMKII underlies enhanced atrial arrhythmogenesis J Yan, W Zhao, JK Thomson, X Gao, DM DeMarco, E Carrillo, B Chen, ... Circulation research 122 (6), 821-835, 2018 | 77 | 2018 |
c-Jun N-terminal kinase activation contributes to reduced connexin43 and development of atrial arrhythmias J Yan, W Kong, Q Zhang, EC Beyer, G Walcott, VG Fast, X Ai Cardiovascular research 97 (3), 589-597, 2013 | 77 | 2013 |
The stress kinase JNK regulates gap junction Cx43 gene expression and promotes atrial fibrillation in the aged heart J Yan, JK Thomson, W Zhao, X Wu, X Gao, D DeMarco, W Kong, M Tong, ... Journal of molecular and cellular cardiology 114, 105-115, 2018 | 64 | 2018 |
Intra–Sarcoplasmic Reticulum Free [Ca2+] and Buffering in Arrhythmogenic Failing Rabbit Heart T Guo, X Ai, TR Shannon, SM Pogwizd, DM Bers Circulation research 101 (8), 802-810, 2007 | 48 | 2007 |
Enhanced activation of p21-activated kinase 1 in heart failure contributes to dephosphorylation of connexin 43 X Ai, A Jiang, Y Ke, RJ Solaro, SM Pogwizd Cardiovascular research 92 (1), 106-114, 2011 | 47 | 2011 |
Calcium/calmodulin-dependent protein kinase II causes atrial structural remodeling associated with atrial fibrillation and heart failure Z Liu, JE Finet, JA Wolfram, ME Anderson, X Ai, JK Donahue Heart Rhythm 16 (7), 1080-1088, 2019 | 44 | 2019 |
Silibinin inhibits NSCLC metastasis by targeting the EGFR/LOX pathway X Hou, H Du, X Quan, L Shi, Q Zhang, Y Wu, Y Liu, J Xiao, Y Li, L Lu, X Ai, ... Frontiers in Pharmacology 9, 21, 2018 | 44 | 2018 |
Connexin43 knockdown or overexpression modulates cell coupling in control and failing rabbit left ventricular myocytes X Ai, W Zhao, SM Pogwizd Cardiovascular research 85 (4), 751-762, 2010 | 42 | 2010 |
Sex differences in repolarization and slow delayed rectifier potassium current and their regulation by sympathetic stimulation in rabbits Y Zhu, X Ai, RA Oster, DM Bers, SM Pogwizd Pflügers Archiv-European Journal of Physiology 465, 805-818, 2013 | 40 | 2013 |
Genetic deletion of Rnd3/RhoE results in mouse heart calcium leakage through upregulation of protein kinase A signaling X Yang, T Wang, X Lin, X Yue, Q Wang, G Wang, Q Fu, X Ai, DY Chiang, ... Circulation research 116 (1), e1-e10, 2015 | 38 | 2015 |
Transcriptional regulation of stress kinase JNK2 in pro-arrhythmic CaMKIIδ expression in the aged atrium X Gao, X Wu, J Yan, J Zhang, W Zhao, D DeMarco, Y Zhang, M Bakhos, ... Cardiovascular research 114 (5), 737-746, 2018 | 36 | 2018 |
Two novel camptothecin derivatives inhibit colorectal cancer proliferation via induction of cell cycle arrest and apoptosis in vitro and in vivo H Du, Y Huang, X Hou, X Quan, J Jiang, X Wei, Y Liu, H Li, P Wang, ... European Journal of Pharmaceutical Sciences 123, 546-559, 2018 | 34 | 2018 |