Understanding the tumor immune microenvironment (TIME) for effective therapy M Binnewies, EW Roberts, K Kersten, V Chan, DF Fearon, M Merad, ... Nature medicine 24 (5), 541-550, 2018 | 4695 | 2018 |
Targeting CXCL12 from FAP-expressing carcinoma-associated fibroblasts synergizes with anti–PD-L1 immunotherapy in pancreatic cancer C Feig, JO Jones, M Kraman, RJB Wells, A Deonarine, DS Chan, ... Proceedings of the National Academy of Sciences 110 (50), 20212-20217, 2013 | 1985 | 2013 |
Suppression of antitumor immunity by stromal cells expressing fibroblast activation protein–α M Kraman, PJ Bambrough, JN Arnold, EW Roberts, L Magiera, JO Jones, ... Science 330 (6005), 827-830, 2010 | 1234 | 2010 |
Critical role for CD103+/CD141+ dendritic cells bearing CCR7 for tumor antigen trafficking and priming of T cell immunity in melanoma EW Roberts, ML Broz, M Binnewies, MB Headley, AE Nelson, DM Wolf, ... Cancer cell 30 (2), 324-336, 2016 | 981 | 2016 |
Tumor microenvironment complexity: emerging roles in cancer therapy MA Swartz, N Iida, EW Roberts, S Sangaletti, MH Wong, FE Yull, ... Cancer research 72 (10), 2473-2480, 2012 | 651 | 2012 |
Unleashing type-2 dendritic cells to drive protective antitumor CD4+ T cell immunity M Binnewies, AM Mujal, JL Pollack, AJ Combes, EA Hardison, KC Barry, ... Cell 177 (3), 556-571. e16, 2019 | 584 | 2019 |
Visualization of immediate immune responses to pioneer metastatic cells in the lung MB Headley, A Bins, A Nip, EW Roberts, MR Looney, A Gerard, ... Nature 531 (7595), 513-517, 2016 | 450 | 2016 |
Depletion of stromal cells expressing fibroblast activation protein-α from skeletal muscle and bone marrow results in cachexia and anemia EW Roberts, A Deonarine, JO Jones, AE Denton, C Feig, SK Lyons, ... Journal of Experimental Medicine 210 (6), 1137-1151, 2013 | 414 | 2013 |
Tumor-induced IL-6 reprograms host metabolism to suppress anti-tumor immunity TR Flint, T Janowitz, CM Connell, EW Roberts, AE Denton, AP Coll, ... Cell metabolism 24 (5), 672-684, 2016 | 359 | 2016 |
Chimeric antigen receptors that trigger phagocytosis MA Morrissey, AP Williamson, AM Steinbach, EW Roberts, N Kern, ... elife 7, e36688, 2018 | 337 | 2018 |
Stromal cells in the tumor microenvironment AE Denton, EW Roberts, DT Fearon Stromal immunology, 99-114, 2018 | 302 | 2018 |
Visualizing synaptic transfer of tumor antigens among dendritic cells MK Ruhland, EW Roberts, E Cai, AM Mujal, K Marchuk, C Beppler, ... Cancer cell 37 (6), 786-799. e5, 2020 | 205 | 2020 |
Fibroblastic reticular cells of the lymph node are required for retention of resting but not activated CD8+ T cells AE Denton, EW Roberts, MA Linterman, DT Fearon Proceedings of the National Academy of Sciences 111 (33), 12139-12144, 2014 | 152 | 2014 |
CXCR2 inhibition enables NASH-HCC immunotherapy J Leslie, JBG Mackey, T Jamieson, E Ramon-Gil, TM Drake, F Fercoq, ... Gut 71 (10), 2093-2106, 2022 | 127 | 2022 |
Control of an unusual photo-Claisen rearrangement in coumarin caged tamoxifen through an extended spacer PT Wong, EW Roberts, S Tang, J Mukherjee, J Cannon, AJ Nip, K Corbin, ... ACS chemical biology 12 (4), 1001-1010, 2017 | 61 | 2017 |
A fluorogenic probe for granzyme B enables in-biopsy evaluation and screening of response to anticancer immunotherapies JI Scott, L Mendive-Tapia, D Gordon, ND Barth, EJ Thompson, Z Cheng, ... Nature communications 13 (1), 2366, 2022 | 36 | 2022 |
Mitochondrial DNA mutations drive aerobic glycolysis to enhance checkpoint blockade response in melanoma M Mahmood, EM Liu, AL Shergold, E Tolla, J Tait-Mulder, A Huerta-Uribe, ... Nature cancer, 1-14, 2024 | 29 | 2024 |
Superinfection exclusion creates spatially distinct influenza virus populations A Sims, LB Tornaletti, S Jasim, C Pirillo, R Devlin, JC Hirst, C Loney, ... PLoS Biology 21 (2), e3001941, 2023 | 24 | 2023 |
Learned adaptive multiphoton illumination microscopy for large-scale immune response imaging H Pinkard, H Baghdassarian, A Mujal, E Roberts, KH Hu, DH Friedman, ... Nature communications 12 (1), 1916, 2021 | 20 | 2021 |
Metalloproteinase inhibition reduces AML growth, prevents stem cell loss, and improves chemotherapy effectiveness C Pirillo, F Birch, FS Tissot, SG Anton, M Haltalli, V Tini, I Kong, C Piot, ... Blood advances 6 (10), 3126-3141, 2022 | 19 | 2022 |