The translation of cell-based therapies: clinical landscape and manufacturing challenges TRJ Heathman, AW Nienow, MJ McCall, K Coopman, B Kara, CJ Hewitt Regenerative medicine 10 (1), 49-64, 2015 | 350 | 2015 |
Culture of human mesenchymal stem cells on microcarriers in a 5 l stirred-tank bioreactor QA Rafiq, KM Brosnan, K Coopman, AW Nienow, CJ Hewitt Biotechnology letters 35 (8), 1233-1245, 2013 | 234 | 2013 |
A potentially scalable method for the harvesting of hMSCs from microcarriers AW Nienow, QA Rafiq, K Coopman, CJ Hewitt Biochemical Engineering Journal 85, 79-88, 2014 | 189 | 2014 |
Systematic microcarrier screening and agitated culture conditions improves human mesenchymal stem cell yield in bioreactors QA Rafiq, K Coopman, AW Nienow, CJ Hewitt Biotechnology journal 11 (4), 473-486, 2016 | 172 | 2016 |
The physical characterisation of a microscale parallel bioreactor platform with an industrial CHO cell line expressing an IgG4 AW Nienow, CD Rielly, K Brosnan, N Bargh, K Lee, K Coopman, ... Biochemical Engineering Journal 76, 25-36, 2013 | 148 | 2013 |
The impact of cryopreservation on bone marrow-derived mesenchymal stem cells: a systematic review S Bahsoun, K Coopman, EC Akam Journal of translational medicine 17 (1), 1-29, 2019 | 110 | 2019 |
Expansion, harvest and cryopreservation of human mesenchymal stem cells in a serum‐free microcarrier process TRJ Heathman, VAM Glyn, A Picken, QA Rafiq, K Coopman, AW Nienow, ... Biotechnology and bioengineering 112 (8), 1696-1707, 2015 | 110 | 2015 |
Agitation conditions for the culture and detachment of hMSCs from microcarriers in multiple bioreactor platforms AW Nienow, CJ Hewitt, TRJ Heathman, VAM Glyn, GN Fonte, MP Hanga, ... Biochemical Engineering Journal 108, 24-29, 2016 | 109 | 2016 |
Characterization of human mesenchymal stem cells from multiple donors and the implications for large scale bioprocess development TRJ Heathman, QA Rafiq, AKC Chan, K Coopman, AW Nienow, B Kara, ... Biochemical Engineering Journal 108, 14-23, 2016 | 107 | 2016 |
Large-scale expansion and exploitation of pluripotent stem cells for regenerative medicine purposes: beyond the T flask AJ Want, AW Nienow, CJ Hewitt, K Coopman Regenerative Medicine 7 (1), 71-84, 2012 | 99 | 2012 |
Scale-up of human mesenchymal stem cell culture: current technologies and future challenges QA Rafiq, K Coopman, CJ Hewitt Current Opinion in Chemical Engineering 2 (1), 8-16, 2013 | 96 | 2013 |
Temporal variation in CB 2 R levels following T lymphocyte activation: evidence that cannabinoids modulate CXCL12-induced chemotaxis K Coopman, LD Smith, KL Wright, SG Ward International immunopharmacology 7 (3), 360-371, 2007 | 83 | 2007 |
Biocompatibility Assessment of Conducting PANI/Chitosan Nanofibers for Wound Healing Applications P Moutsatsou, K Coopman, S Georgiadou Polymers 9 (12), 687, 2017 | 79 | 2017 |
Residues within the Transmembrane Domain of the Glucagon-Like Peptide-1 Receptor Involved in Ligand Binding and Receptor Activation: Modelling the Ligand-Bound Receptor K Coopman, R Wallis, G Robb, AJH Brown, GF Wilkinson, D Timms, ... Molecular Endocrinology 25 (10), 1804-1818, 2011 | 66 | 2011 |
Comparative effects of the endogenous agonist glucagon-like peptide-1 (GLP-1)-(7-36) amide and the small-molecule ago-allosteric agent “compound 2” at the GLP-1 receptor K Coopman, Y Huang, N Johnston, SJ Bradley, GF Wilkinson, GB Willars Journal of Pharmacology and Experimental Therapeutics 334 (3), 795-808, 2010 | 63 | 2010 |
Conductive PANI fibers and determining factors for the electrospinning window P Moutsatsou, K Coopman, MB Smith, S Georgiadou Polymer 77, 143-151, 2015 | 57 | 2015 |
Serum-free process development: improving the yield and consistency of human mesenchymal stromal cell production TRJ Heathman, A Stolzing, C Fabian, QA Rafiq, K Coopman, AW Nienow, ... Cytotherapy 17 (11), 1524-1535, 2015 | 55 | 2015 |
From production to patient: challenges and approaches for delivering cell therapies K Coopman, N Medcalf | 55 | 2014 |
Qualitative and quantitative demonstration of bead-to-bead transfer with bone marrow-derived human mesenchymal stem cells on microcarriers: Utilising the phenomenon to improve … QA Rafiq, S Ruck, MP Hanga, TRJ Heathman, K Coopman, AW Nienow, ... Biochemical engineering journal 135, 11-21, 2018 | 54 | 2018 |
Process development of human multipotent stromal cell microcarrier culture using an automated high‐throughput microbioreactor QA Rafiq, MP Hanga, TRJ Heathman, K Coopman, AW Nienow, ... Biotechnology and bioengineering 114 (10), 2253-2266, 2017 | 54 | 2017 |