Disruption of mitochondrial dynamics affects behaviour and lifespan in Caenorhabditis elegans JJ Byrne, MS Soh, G Chandhok, T Vijayaraghavan, JS Teoh, S Crawford, ... Cellular and Molecular Life Sciences 76, 1967-1985, 2019 | 95 | 2019 |
High-Throughput Phenotypic Assay to Screen for Anthelmintic Activity on Haemonchus contortus AC Taki, JJ Byrne, T Wang, BE Sleebs, N Nguyen, RS Hall, PK Korhonen, ... Pharmaceuticals 14 (7), 616, 2021 | 35 | 2021 |
A high-throughput phenotypic screen of the ‘Pandemic Response Box’identifies a quinoline derivative with significant anthelmintic activity HT Shanley, AC Taki, JJ Byrne, A Jabbar, TNC Wells, K Samby, PR Boag, ... Pharmaceuticals 15 (2), 257, 2022 | 16 | 2022 |
Practical High-Throughput Method to Screen Compounds for Anthelmintic Activity against Caenorhabditis elegans AC Taki, JJ Byrne, PR Boag, A Jabbar, RB Gasser Molecules 26 (14), 4156, 2021 | 15 | 2021 |
Thermal proteome profiling reveals Haemonchus orphan protein HCO_011565 as a target of the nematocidal small molecule UMW-868 AC Taki, T Wang, NN Nguyen, CS Ang, MG Leeming, S Nie, JJ Byrne, ... Frontiers in Pharmacology 13, 1014804, 2022 | 11 | 2022 |
High Throughput Screening of the NatureBank ‘Marine Collection’ in a Haemonchus Bioassay Identifies Anthelmintic Activity in Extracts from a Range of Sponges … AC Taki, JJ Byrne, A Jabbar, KY Lum, S Hayes, RS Addison, KS Ramage, ... Molecules 26 (19), 5846, 2021 | 11 | 2021 |
A phenotypic screen of the Global Health Priority Box identifies an insecticide with anthelmintic activity HT Shanley, AC Taki, JJ Byrne, N Nguyen, TNC Wells, A Jabbar, ... Parasites & Vectors 17 (1), 131, 2024 | 8 | 2024 |
Identification of Anthelmintic Bishomoscalarane Sesterterpenes from the Australian Marine Sponge Phyllospongia bergquistae and Structure Revision of … S Hayes, AC Taki, KY Lum, JJ Byrne, JM White, MG Ekins, RB Gasser, ... Journal of Natural Products 85 (7), 1723-1729, 2022 | 8 | 2022 |
Dysidenin from the Marine Sponge Citronia sp. Affects the Motility and Morphology of Haemonchus contortus Larvae In Vitro KS Ramage, AC Taki, KY Lum, S Hayes, JJ Byrne, T Wang, A Hofmann, ... Marine Drugs 19 (12), 698, 2021 | 5 | 2021 |
Design, synthesis and screening of a drug discovery library based on an Eremophila-derived serrulatane scaffold C Zhang, KY Lum, AC Taki, RB Gasser, JJ Byrne, T Wang, ... Phytochemistry 190, 112887, 2021 | 5 | 2021 |
Structure-activity relationship and target investigation of 2-aryl quinolines with nematocidal activity HT Shanley, AC Taki, N Nguyen, T Wang, JJ Byrne, CS Ang, MG Leeming, ... International Journal for Parasitology: Drugs and Drug Resistance 24, 100522, 2024 | 4 | 2024 |
Using UHPLC–MS profiling for the discovery of new sponge-derived metabolites and anthelmintic screening of the NatureBank bromotyrosine library S Hayes, AC Taki, KY Lum, JJ Byrne, MG Ekins, RB Gasser, RA Davis Beilstein journal of organic chemistry 18 (1), 1544-1552, 2022 | 4 | 2022 |
Analysis of Haemonchus embryos at single cell resolution identifies two eukaryotic elongation factors as intervention target candidates PK Korhonen, T Wang, ND Young, JJ Byrne, TL Campos, BCH Chang, ... Computational and Structural Biotechnology Journal 23, 1026-1035, 2024 | 3 | 2024 |
Three Small Molecule Entities (MPK18, MPK334 and YAK308) with Activity against Haemonchus contortus In Vitro AC Taki, A Jabbar, T Kurz, B Lungerich, G Ma, JJ Byrne, M Pflieger, ... Molecules 26 (9), 2819, 2021 | 3 | 2021 |
Quantitative approaches for studying cellular structures and organelle morphology in Caenorhabditis elegans JS Teoh, MS Soh, JJ Byrne, B Neumann JoVE (Journal of Visualized Experiments), e59978, 2019 | 3 | 2019 |
Structure activity relationship and target prediction for ABX464 analogues in Caenorhabditis elegans HT Shanley, AC Taki, N Nguyen, T Wang, JJ Byrne, CS Ang, MG Leeming, ... Bioorganic & Medicinal Chemistry 98, 117540, 2024 | 2 | 2024 |
Using a Bioactive Eremophila-Derived Serrulatane Scaffold to Generate a Unique Carbamate Library for Anti-infective Evaluations C Zhang, KY Lum, AC Taki, RB Gasser, JJ Byrne, LJ Montaner, I Tietjen, ... Journal of Natural Products 86 (3), 557-565, 2023 | 2 | 2023 |
Chromosome-contiguous genome for the Haecon-5 strain of Haemonchus contortus reveals marked genetic variability and enables the discovery of essential gene candidates Y Zheng, ND Young, TL Campos, PK Korhonen, T Wang, SB Sumanam, ... International Journal for Parasitology 54 (13), 705-715, 2024 | 1 | 2024 |
Comparative structure activity and target exploration of 1, 2-diphenylethynes in Haemonchus contortus and Caenorhabditis elegans HT Shanley, AC Taki, N Nguyen, T Wang, JJ Byrne, CS Ang, MG Leeming, ... International Journal for Parasitology: Drugs and Drug Resistance 25, 100534, 2024 | 1 | 2024 |
Anthelmintic activity of selected neolignans and semisynthetic derivatives from Styrax suberifolius K Wijesekera, AC Taki, JJ Byrne, JM White, AR Carroll, RB Gasser, ... Tetrahedron 169, 134366, 2025 | | 2025 |