Synthesis, biological evaluation and docking study of 1,3,4-thiadiazole-thiazolidinone hybrids as anti-inflammatory agents with dual inhibition of COX-2 and 15-LOX Y Omar, H Abdu-Allah, S Abdel-Moty Bioorganic Chemistry, 2018 | 72 | 2018 |
Further insight into the dual COX-2 and 15-LOX anti-inflammatory activity of 1,3,4-thiadiazole-thiazolidinone hybrids: The contribution of the substituents at 5th positions is … HHMAA Yasser M. Omar, Samia G. Abdel-Moty Bioorganic Chemistry, 2020 | 65 | 2020 |
Design and synthesis of novel 2, 3-dihydropyrazino [1, 2-a] indole-1, 4-dione derivatives as antiproliferative EGFR and BRAFV600E dual inhibitors LH Al-Wahaibi, AM Gouda, OF Abou-Ghadir, OIA Salem, AT Ali, ... Bioorganic Chemistry 104, 104260, 2020 | 61 | 2020 |
5-Aminosalyclic Acid (5-ASA): A Unique Anti-Inflammatory Salicylate HHM Abdu-Allah, ANA El-Shorbagi, SG Abdel-Moty, EA Raafat, ... Medicinal chemistry-OMICS International 6 (5), 306-315, 2016 | 58 | 2016 |
Click chemistry synthesis, biological evaluation and docking study of some novel 2’-hydroxychalcone-triazole hybrids as potent anti-inflammatory agents AN Boshra, HHM Abdu-Allah, AF Mohammed, AM Hayallah Bioorganic Chemistry, 2019 | 55 | 2019 |
CD22-antagonists with nanomolar potency: the synergistic effect of hydrophobic groups at C-2 and C-9 of sialic acid scaffold HHM Abdu-Allah, K Watanabe, GC Completo, M Sadagopan, ... Bioorganic & medicinal chemistry 19 (6), 1966-1971, 2011 | 43 | 2011 |
Design, synthesis, and structure− affinity relationships of novel series of sialosides as CD22-specific inhibitors HHM Abdu-Allah, T Tamanaka, J Yu, L Zhuoyuan, M Sadagopan, ... Journal of medicinal chemistry 51 (21), 6665-6681, 2008 | 41 | 2008 |
Inhibition of SHP2 by new compounds induces differential effects on RAS/RAF/ERK and PI3K/AKT pathways in different cancer cell types CG Vazhappilly, E Saleh, W Ramadan, V Menon, AM Al-Azawi, H Tarazi, ... Investigational New Drugs 37, 252–261, 2019 | 39 | 2019 |
Synthesis of some benzimidazole derivatives endowed with 1,2,3-triazole as potential inhibitors of hepatitis C virus BGM Youssif, YAM Mohamed, MTA Salim, F Inagaki, C Mukai, ... Acta Pharmaceutica, 2016 | 35 | 2016 |
Proximity labeling of cis-ligands of CD22/Siglec-2 reveals stepwise α2,6 sialic acid-dependent and -independent interactions AA Deh Sheikh, C Akatsua, A Imamura, Abdu-Allah, H H. M., ... Biochemical and Biophysical Research Communications 495 (1), 854-859, 2018 | 32 | 2018 |
CD22-binding synthetic sialosides regulate B lymphocyte proliferation through CD22 ligand-dependent and independent pathways, and enhance antibody production in mice N Matsubara, A Imamura, T Yonemizu, C Akatsu, H Yang, A Ueki, ... Frontiers in immunology 9, 820, 2018 | 31 | 2018 |
Design and synthesis of novel 5-aminosalicylate (5-ASA)–4-thiazolinone hybrid derivatives with promising antiproliferative activity HHM Abdu-Allah, SG Abdel-Moty, R El-Awady, ANA El-Shorbagi Bioorganic & medicinal chemistry letters 26 (7), 1647-1650, 2016 | 28 | 2016 |
Induction of DNA damage, apoptosis and cell cycle perturbation mediate cytotoxic activity of new 5-aminosalicylate–4-thiazolinone hybrid derivatives WS Ramadan, EM Saleh, V Menon, CG Vazhappilly, HHM abdu-Allah, ... Biomedicine & Pharmacotherapy 131, 110571, 2020 | 27 | 2020 |
Synthesis and anti-inflammatory testing of some new compounds incorporating 5-aminosalicylic acid (5-ASA) as potential prodrugs AAM Abdel-Alim, ANA El-Shorbagi, SG Abdel-Moty, HHM Abdel-Allah Archives of pharmacal research 28, 637-647, 2005 | 25 | 2005 |
Potent small molecule mouse CD22-inhibitors: Exploring the interaction of the residue at C-2 of sialic acid scaffold HHM Abdu-Allah, K Watanabe, K Hayashizaki, C Takaku, T Tamanaka, ... Bioorganic & medicinal chemistry letters 19 (19), 5573-5575, 2009 | 24 | 2009 |
Novel N-substituted 5–aminosalicylamides as dual inhibitors of cyclooxygenase and 5-lipoxygenase enzymes: Synthesis, biological evaluation and docking study MKS El-Nagar, HHM Abdu-Allah, OIA Salem, AHN Kafafy, HSM Farghaly Bioorganic Chemistry, 2018 | 23 | 2018 |
Synthesis and anti-mycobacterial activity of 4-(4-phenyl-1H-1,2,3-triazol-1- yl)salicylhydrazones: revitalizing an old drug HHM Abdu-Allah, BGM Youssif, MH Abdelrahman, MK Abdel-Hamid, ... Archives of Pharmacal Research 40 (2), 168-179., 2017 | 20 | 2017 |
Bis-(5-substituted-2-thiono-1,3,5-thiadiazinan-3-yl) butane as a scaffold of anti-proliferative activity, blended by a multicomponent process HO Abdel-Nasser El-Shorbagi, Mohamed El-Naggar, Hamadeh Tarazi, Sachin ... Medicinal Chemistry Research, 1-8, 2018 | 18* | 2018 |
Conjugation of 4-aminosalicylate with thiazolinones afforded non-cytotoxic potent in vitro and in vivo anti-inflammatory hybrids HHM Abdu-Allah, AAB Abdelmoez, H Tarazi, ANA El-Shorbagi, ... Bioorganic Chemistry 94, 103378, 2020 | 17 | 2020 |
The Protein Tyrosine Phosphatase SHP-1 (PTPN6) but Not CD45 (PTPRC) Is Essential for the Ligand-Mediated Regulation of CD22 in BCR-Ligated B Cells TT Amin Alborzian Deh Sheikh, Chizuru Akatsu, Hajjaj Abdu-allah, Yuki ... The Journal of Immunology, 2021 | 13 | 2021 |