| Single luminal epithelial progenitors can generate prostate organoids in culture CW Chua, M Shibata, M Lei, R Toivanen, LMJ Barlow, SK Bergren, ... Nature cell biology 16 (10), 951-961, 2014 | 393 | 2014 |
| Transdifferentiation as a mechanism of treatment resistance in a mouse model of castration-resistant prostate cancer M Zou, R Toivanen, A Mitrofanova, N Floch, S Hayati, Y Sun, ... Cancer discovery 7 (7), 736-749, 2017 | 359 | 2017 |
| Prostate organogenesis: tissue induction, hormonal regulation and cell type specification R Toivanen, MM Shen Development 144 (8), 1382-1398, 2017 | 279 | 2017 |
| Estrogen receptor–β activated apoptosis in benign hyperplasia and cancer of the prostate is androgen independent and TNFα mediated SJ McPherson, S Hussain, P Balanathan, SL Hedwards, B Niranjan, ... Proceedings of the National Academy of Sciences 107 (7), 3123-3128, 2010 | 240 | 2010 |
| Luminal cells are favored as the cell of origin for prostate cancer ZA Wang, R Toivanen, SK Bergren, P Chambon, MM Shen Cell reports 8 (5), 1339-1346, 2014 | 176 | 2014 |
| Patient-derived xenografts reveal that intraductal carcinoma of the prostate is a prominent pathology in BRCA2 mutation carriers with prostate cancer and correlates with poor … GP Risbridger, RA Taylor, D Clouston, A Sliwinski, H Thorne, S Hunter, ... European Urology 67 (3), 496-503, 2015 | 159 | 2015 |
| A preclinical xenograft model of prostate cancer using human tumors MG Lawrence, RA Taylor, R Toivanen, J Pedersen, S Norden, DW Pook, ... Nature protocols 8 (5), 836-848, 2013 | 123 | 2013 |
| Human epithelial basal cells are cells of origin of prostate cancer, independent of CD133 status RA Taylor, R Toivanen, M Frydenberg, J Pedersen, L Harewood, ... Stem cells 30 (6), 1087-1096, 2012 | 116 | 2012 |
| Stem cells in prostate cancer: treating the root of the problem RA Taylor, R Toivanen, GP Risbridger Endocrine-related cancer 17 (4), R273-R285, 2010 | 109 | 2010 |
| Patient-derived models of abiraterone-and enzalutamide-resistant prostate cancer reveal sensitivity to ribosome-directed therapy MG Lawrence, D Obinata, S Sandhu, LA Selth, SQ Wong, LH Porter, ... European urology 74 (5), 562-572, 2018 | 106 | 2018 |
| Stromal androgen receptor regulates the composition of the microenvironment to influence prostate cancer outcome DA Leach, EF Need, R Toivanen, AP Trotta, HM Palenthorpe, DJ Tamblyn, ... Oncotarget 6 (18), 16135, 2015 | 93 | 2015 |
| Preclinical models of prostate cancer: patient-derived xenografts, organoids, and other explant models GP Risbridger, R Toivanen, RA Taylor Cold Spring Harbor perspectives in medicine 8 (8), a030536, 2018 | 84 | 2018 |
| Transdifferentiation as a mechanism of treatment resistance in a mouse model of castration-resistant prostate cancer. Cancer Discov. 2017; 7: 736–749. doi: 10.1158/2159-8290 M Zou, R Toivanen, A Mitrofanova, N Floch, S Hayati, Y Sun, ... Nat Neurosci 15, 215-223, 2011 | 79 | 2011 |
| Basal progenitors contribute to repair of the prostate epithelium following induced luminal anoikis R Toivanen, A Mohan, MM Shen Stem cell reports 6 (5), 660-667, 2016 | 73 | 2016 |
| A preclinical xenograft model identifies castration-tolerant cancer-repopulating cells in localized prostate tumors R Toivanen, M Frydenberg, D Murphy, J Pedersen, A Ryan, D Pook, ... Science translational medicine 5 (187), 187ra71-187ra71, 2013 | 64 | 2013 |
| The MURAL collection of prostate cancer patient-derived xenografts enables discovery through preclinical models of uro-oncology GP Risbridger, AK Clark, LH Porter, R Toivanen, A Bakshi, NL Lister, ... Nature communications 12 (1), 5049, 2021 | 55 | 2021 |
| Brief report: a bioassay to identify primary human prostate cancer repopulating cells R Toivanen, DM Berman, H Wang, J Pedersen, M Frydenberg, AK Meeker, ... Stem Cells 29 (8), 1310-1314, 2011 | 49 | 2011 |
| Breaking through a roadblock in prostate cancer research: an update on human model systems R Toivanen, RA Taylor, DW Pook, SJ Ellem, GP Risbridger The Journal of steroid biochemistry and molecular biology 131 (3-5), 122-131, 2012 | 48 | 2012 |
| Neuroendocrine cells in prostate cancer correlate with poor outcomes: a systematic review and meta‐analysis A Kannan, D Clouston, M Frydenberg, D Ilic, MN Karim, SM Evans, ... BJU international 130 (4), 420-433, 2022 | 8 | 2022 |
| A balancing act: PHLPP2 fine tunes AKT activity and MYC stability in prostate cancer R Toivanen, L Furic The Journal of Cell Biology 218 (6), 1771, 2019 | 6 | 2019 |
