Tumor heterogeneity reshapes the tumor microenvironment to influence drug resistance A Zhang, K Miao, H Sun, CX Deng International journal of biological sciences 18 (7), 3019, 2022 | 141 | 2022 |
Genetic targeting of sprouting angiogenesis using Apln-CreER Q Liu, T Hu, L He, X Huang, X Tian, H Zhang, L He, W Pu, L Zhang, H Sun, ... Nature communications 6 (1), 6020, 2015 | 137 | 2015 |
Pyruvate kinase type M2 is upregulated in colorectal cancer and promotes proliferation and migration of colon cancer cells CF Zhou, XB Li, H Sun, B Zhang, YS Han, Y Jiang, QL Zhuang, J Fang, ... IUBMB life 64 (9), 775-782, 2012 | 119 | 2012 |
TRAF6 upregulates expression of HIF-1α and promotes tumor angiogenesis H Sun, XB Li, Y Meng, L Fan, M Li, J Fang Cancer Research 73 (15), 4950-4959, 2013 | 111 | 2013 |
Patient‐derived organoids can guide personalized‐therapies for patients with advanced breast cancer P Chen, X Zhang, R Ding, L Yang, X Lyu, J Zeng, JH Lei, L Wang, J Bi, ... Advanced Science 8 (22), 2101176, 2021 | 108 | 2021 |
Drug screening of cancer cell lines and human primary tumors using droplet microfluidics AHH Wong, H Li, Y Jia, PI Mak, RPS Martins, Y Liu, CM Vong, HC Wong, ... Scientific reports 7 (1), 9109, 2017 | 105 | 2017 |
NOTCH1 activation compensates BRCA1 deficiency and promotes triple-negative breast cancer formation K Miao, JH Lei, MV Valecha, A Zhang, J Xu, L Wang, X Lyu, S Chen, ... Nature communications 11 (1), 3256, 2020 | 93 | 2020 |
Potential therapeutic targets of triple-negative breast cancer based on its intrinsic subtype F Shao, H Sun, CX Deng Oncotarget 8 (42), 73329, 2017 | 80 | 2017 |
TRAF6 is upregulated in colon cancer and promotes proliferation of colon cancer cells H Sun, X Li, L Fan, G Wu, M Li, J Fang The international journal of biochemistry & cell biology 53, 195-201, 2014 | 77 | 2014 |
Molecular landscape and subtype-specific therapeutic response of nasopharyngeal carcinoma revealed by integrative pharmacogenomics RB Ding, P Chen, BK Rajendran, X Lyu, H Wang, J Bao, J Zeng, W Hao, ... Nature communications 12 (1), 3046, 2021 | 70 | 2021 |
PHD3 stabilizes the tight junction protein occludin and protects intestinal epithelial barrier function Y Chen, HS Zhang, GH Fong, QL Xi, GH Wu, CG Bai, ZQ Ling, L Fan, ... Journal of Biological Chemistry 290 (33), 20580-20589, 2015 | 65 | 2015 |
CRISPR-Cas9: from genome editing to cancer research S Chen, H Sun, K Miao, CX Deng International journal of biological sciences 12 (12), 1427, 2016 | 61 | 2016 |
S100A9-CXCL12 activation in BRCA1-mutant breast cancer promotes an immunosuppressive microenvironment associated with resistance to immunotherapy J Li, X Shu, J Xu, SM Su, UI Chan, L Mo, J Liu, X Zhang, R Adhav, Q Chen, ... Nature communications 13 (1), 1481, 2022 | 58 | 2022 |
Single-cell RNA-Seq reveals cell heterogeneity and hierarchy within mouse mammary epithelia H Sun, Z Miao, X Zhang, UI Chan, SM Su, S Guo, CKH Wong, X Xu, ... Journal of Biological Chemistry 293 (22), 8315-8329, 2018 | 52 | 2018 |
The orphan nuclear receptor EAR2 is overexpressed in colorectal cancer and it regulates survivability of colon cancer cells X Li, S Jiao, H Sun, J Xue, W Zhao, L Fan, G Wu, J Fang Cancer letters 309 (2), 137-144, 2011 | 45 | 2011 |
Characterization of BRCA1-deficient premalignant tissues and cancers identifies Plekha5 as a tumor metastasis suppressor J Liu, R Adhav, K Miao, SM Su, L Mo, UI Chan, X Zhang, J Xu, J Li, X Shu, ... Nature communications 11 (1), 4875, 2020 | 32 | 2020 |
Benzo [a] pyrene induces expression of matrix metalloproteinases and cell migration and invasion of vascular smooth muscle cells D Meng, DD Lv, X Zhuang, H Sun, L Fan, XL Shi, J Fang Toxicology letters 184 (1), 44-49, 2009 | 30 | 2009 |
Activation of FGFR2 signaling suppresses BRCA1 and drives triple‐negative mammary tumorigenesis that is sensitive to immunotherapy JH Lei, MH Lee, K Miao, Z Huang, Z Yao, A Zhang, J Xu, M Zhao, ... Advanced Science 8 (21), 2100974, 2021 | 29 | 2021 |
Accelerating precision anti-cancer therapy by time-lapse and label-free 3D tumor slice culture platform F Xing, YC Liu, S Huang, X Lyu, SM Su, UI Chan, PC Wu, Y Yan, N Ai, J Li, ... Theranostics 11 (19), 9415, 2021 | 24 | 2021 |
pVHL mediates K63-linked ubiquitination of nCLU J Xue, D Lv, S Jiao, W Zhao, X Li, H Sun, B Yan, L Fan, R Hu, J Fang PLoS One 7 (4), e35848, 2012 | 23 | 2012 |