A rat model of ataxia-telangiectasia: evidence for a neurodegenerative phenotype H Quek, J Luff, KG Cheung, S Kozlov, M Gatei, CS Lee, MC Bellingham, ... Human molecular genetics 26 (1), 109-123, 2017 | 87 | 2017 |
Altered brain endothelial cell phenotype from a familial Alzheimer mutation and its potential implications for amyloid clearance and drug delivery LE Oikari, R Pandit, R Stewart, C Cuní-López, H Quek, R Sutharsan, ... Stem cell reports 14 (5), 924-939, 2020 | 77 | 2020 |
Chronic stress and A lzheimer's disease: the interplay between the hypothalamic–pituitary–adrenal axis, genetics and microglia A Milligan Armstrong, T Porter, H Quek, A White, J Haynes, C Jackaman, ... Biological Reviews 96 (5), 2209-2228, 2021 | 76 | 2021 |
ALS monocyte-derived microglia-like cells reveal cytoplasmic TDP-43 accumulation, DNA damage, and cell-specific impairment of phagocytosis associated with disease progression H Quek, C Cuní-López, R Stewart, T Colletti, A Notaro, TH Nguyen, Y Sun, ... Journal of neuroinflammation 19 (1), 1-21, 2022 | 72 | 2022 |
Rats with a missense mutation in Atm display neuroinflammation and neurodegeneration subsequent to accumulation of cytosolic DNA following unrepaired DNA damage H Quek, J Luff, KG Cheung, S Kozlov, M Gatei, CS Lee, MC Bellingham, ... Journal of Leucocyte Biology 101 (4), 927-947, 2017 | 51 | 2017 |
The Syk–NFAT–IL-2 pathway in dendritic cells is required for optimal sterile immunity elicited by alum adjuvants HJ Khameneh, AWS Ho, R Spreafico, H Derks, HQY Quek, A Mortellaro The Journal of Immunology 198 (1), 196-204, 2017 | 31 | 2017 |
CuII(atsm) Attenuates Neuroinflammation XY Choo, JR Liddell, MT Huuskonen, A Grubman, D Moujalled, J Roberts, ... Frontiers in neuroscience 12, 668, 2018 | 27 | 2018 |
Dual targeting of chromatin stability by the curaxin CBL0137 and histone deacetylase inhibitor panobinostat shows significant preclinical efficacy in neuroblastoma L Xiao, K Somers, J Murray, R Pandher, M Karsa, E Ronca, A Bongers, ... Clinical Cancer Research 27 (15), 4338-4352, 2021 | 26 | 2021 |
Simultaneous targeting of DNA replication and homologous recombination in glioblastoma with a polyether ionophore YC Lim, KS Ensbey, C Offenhäuser, RCJ D’souza, JK Cullen, BW Stringer, ... Neuro-oncology 22 (2), 216-228, 2020 | 18 | 2020 |
An alzheimer’s disease patient-derived olfactory stem cell model identifies gene expression changes associated with cognition LM Rantanen, M Bitar, R Lampinen, R Stewart, H Quek, LE Oikari, ... Cells 11 (20), 3258, 2022 | 17 | 2022 |
Novel Anti-Neuroinflammatory Properties of a Thiosemicarbazone–Pyridylhydrazone Copper (II) Complex XY Choo, LE McInnes, A Grubman, JM Wasielewska, I Belaya, E Burrows, ... International Journal of Molecular Sciences 23 (18), 10722, 2022 | 13 | 2022 |
PIKK ing a way to regulate inflammation H Quek, YC Lim, MF Lavin, TL Roberts Immunology and cell biology 96 (1), 8-20, 2018 | 13 | 2018 |
The role of chaperone-mediated autophagy in Bortezomib resistant multiple myeloma N Nikesitch, P Rebeiro, LL Ho, S Pothula, XM Wang, T Khong, H Quek, ... Cells 10 (12), 3464, 2021 | 12 | 2021 |
Recent advances in microglia modelling to address translational outcomes in neurodegenerative diseases C Cuní-López, R Stewart, H Quek, AR White Cells 11 (10), 1662, 2022 | 11 | 2022 |
ATM inhibition prevents interleukin-6 from contributing to the proliferation of glioblastoma cells after ionizing radiation YC Lim, H Quek, C Offenhäuser, S Fazry, A Boyd, M Lavin, T Roberts, ... Journal of Neuro-Oncology 138, 509-518, 2018 | 9 | 2018 |
Advanced patient-specific microglia cell models for pre-clinical studies in Alzheimer’s disease C Cuní-López, R Stewart, LE Oikari, TH Nguyen, TL Roberts, Y Sun, ... Journal of neuroinflammation 21 (1), 50, 2024 | 7 | 2024 |
SMG1 heterozygosity exacerbates haematopoietic cancer development in Atm null mice by increasing persistent DNA damage and oxidative stress U Ho, J Luff, A James, CS Lee, H Quek, HC Lai, S Apte, YC Lim, MF Lavin, ... Journal of Cellular and Molecular Medicine 23 (12), 8151-8160, 2019 | 7 | 2019 |
Regulation of RNA degradation pathways during the lipopolysaccharide response in Macrophages HC Lai, A James, J Luff, P De Souza, H Quek, U Ho, MF Lavin, TL Roberts Journal of Leucocyte Biology 109 (3), 593-603, 2021 | 6 | 2021 |
A robust approach to differentiate human monocyte-derived microglia from peripheral blood mononuclear cells H Quek, C Cuní-López, R Stewart, YC Lim, TL Roberts, AR White STAR protocols 3 (4), 101747, 2022 | 5 | 2022 |
3D models of Alzheimer’s disease patient microglia recapitulate disease phenotype and show differential drug responses compared to 2D C Cuní-López, H Quek, LE Oikari, R Stewart, TH Nguyen, Y Sun, CC Guo, ... bioRxiv, 2021.03. 17.435758, 2021 | 5 | 2021 |