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Laura Gathercole
Laura Gathercole
Verified email at brookes.ac.uk
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Cited by
Year
Glucagon-like peptide 1 decreases lipotoxicity in non-alcoholic steatohepatitis
MJ Armstrong, D Hull, K Guo, D Barton, JM Hazlehurst, LL Gathercole, ...
Journal of hepatology 64 (2), 399-408, 2016
4802016
11β-HSD1 is the major regulator of the tissue-specific effects of circulating glucocorticoid excess
SA Morgan, EL McCabe, LL Gathercole, ZK Hassan-Smith, DP Larner, ...
Proceedings of the National Academy of Sciences 111 (24), E2482-E2491, 2014
3012014
11β-Hydroxysteroid dehydrogenase 1: translational and therapeutic aspects
LL Gathercole, GG Lavery, SA Morgan, MS Cooper, AJ Sinclair, ...
Endocrine reviews 34 (4), 525-555, 2013
2202013
11β-hydroxysteroid dehydrogenase type 1 regulates glucocorticoid-induced insulin resistance in skeletal muscle
SA Morgan, M Sherlock, LL Gathercole, GG Lavery, C Lenaghan, ...
Diabetes 58 (11), 2506-2515, 2009
2092009
Regulation of lipogenesis by glucocorticoids and insulin in human adipose tissue
LL Gathercole, SA Morgan, IJ Bujalska, D Hauton, PM Stewart, ...
PloS one 6 (10), e26223, 2011
1932011
A novel selective 11β-hydroxysteroid dehydrogenase type 1 inhibitor prevents human adipogenesis
IJ Bujalska, LL Gathercole, JW Tomlinson, C Darimont, J Ermolieff, ...
The Journal of endocrinology 197 (2), 297, 2008
1152008
Targeting the pre-receptor metabolism of cortisol as a novel therapy in obesity and diabetes
LL Gathercole, PM Stewart
The Journal of steroid biochemistry and molecular biology 122 (1-3), 21-27, 2010
1112010
Glucocorticoid modulation of insulin signaling in human subcutaneous adipose tissue
LL Gathercole, IJ Bujalska, PM Stewart, JW Tomlinson
The Journal of Clinical Endocrinology & Metabolism 92 (11), 4332-4339, 2007
1032007
Lack of significant metabolic abnormalities in mice with liver-specific disruption of 11β-hydroxysteroid dehydrogenase type 1
GG Lavery, AE Zielinska, LL Gathercole, B Hughes, N Semjonous, ...
Endocrinology 153 (7), 3236-3248, 2012
842012
Glucocorticoids fail to cause insulin resistance in human subcutaneous adipose tissue in vivo
JM Hazlehurst, LL Gathercole, M Nasiri, MJ Armstrong, S Borrows, J Yu, ...
The Journal of Clinical Endocrinology & Metabolism 98 (4), 1631-1640, 2013
742013
AKR1D1 is a novel regulator of metabolic phenotype in human hepatocytes and is dysregulated in non-alcoholic fatty liver disease
N Nikolaou, LL Gathercole, L Marchand, S Althari, NJ Dempster, ...
Metabolism 99, 67-80, 2019
722019
Effect of insulin on AKR1C3 expression in female adipose tissue: in-vivo and in-vitro study of adipose androgen generation in polycystic ovary syndrome
M O'Reilly, L Gathercole, F Capper, W Arlt, J Tomlinson
The Lancet 385, S16, 2015
672015
Dehydroepiandrosterone exerts antiglucocorticoid action on human preadipocyte proliferation, differentiation, and glucose uptake
JC McNelis, KN Manolopoulos, LL Gathercole, IJ Bujalska, PM Stewart, ...
American Journal of Physiology-Endocrinology and Metabolism 305 (9), E1134-E1144, 2013
672013
5α-Reductase type 2 regulates glucocorticoid action and metabolic phenotype in human hepatocytes
M Nasiri, N Nikolaou, S Parajes, NP Krone, G Valsamakis, G Mastorakos, ...
Endocrinology 156 (8), 2863-2871, 2015
532015
Tissue specific regulation of glucocorticoids in severe obesity and the response to significant weight loss following bariatric surgery (BARICORT)
CP Woods, M Corrigan, L Gathercole, A Taylor, B Hughes, G Gaoatswe, ...
The Journal of Clinical Endocrinology & Metabolism 100 (4), 1434-1444, 2015
522015
Adipocyte differentiation, mitochondrial gene expression and fat distribution: differences between zidovudine and tenofovir after 6 months
M Boothby, KC McGee, JW Tomlinson, LL Gathercole, PG McTernan, ...
Antiviral Therapy 14 (8), 1089-1100, 2009
452009
Regulation of lipid metabolism by glucocorticoids and 11β-HSD1 in skeletal muscle
SA Morgan, LL Gathercole, C Simonet, ZK Hassan-Smith, I Bujalska, ...
Endocrinology 154 (7), 2374-2384, 2013
392013
Hormonal regulation of lipogenesis
LL Gathercole, SA Morgan, JW Tomlinson
Vitamins & hormones 91, 1-27, 2013
382013
Advanced non‐alcoholic fatty liver disease and adipose tissue fibrosis in patients with Alström syndrome
LL Gathercole, JM Hazlehurst, MJ Armstrong, R Crowley, S Boocock, ...
Liver International 36 (11), 1704-1712, 2016
352016
The Role of 11ß-Hydroxysteroid Dehydrogenase 1 in Adipogenesis in Thyroid-Associated Ophthalmopathy
JW Tomlinson, OM Durrani, IJ Bujalska, LL Gathercole, PJ Tomlins, ...
The Journal of Clinical Endocrinology & Metabolism 95 (1), 398-406, 2010
332010
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