Glucagon-like peptide 1 decreases lipotoxicity in non-alcoholic steatohepatitis MJ Armstrong, D Hull, K Guo, D Barton, JM Hazlehurst, LL Gathercole, ... Journal of hepatology 64 (2), 399-408, 2016 | 480 | 2016 |
11β-HSD1 is the major regulator of the tissue-specific effects of circulating glucocorticoid excess SA Morgan, EL McCabe, LL Gathercole, ZK Hassan-Smith, DP Larner, ... Proceedings of the National Academy of Sciences 111 (24), E2482-E2491, 2014 | 301 | 2014 |
11β-Hydroxysteroid dehydrogenase 1: translational and therapeutic aspects LL Gathercole, GG Lavery, SA Morgan, MS Cooper, AJ Sinclair, ... Endocrine reviews 34 (4), 525-555, 2013 | 220 | 2013 |
11β-hydroxysteroid dehydrogenase type 1 regulates glucocorticoid-induced insulin resistance in skeletal muscle SA Morgan, M Sherlock, LL Gathercole, GG Lavery, C Lenaghan, ... Diabetes 58 (11), 2506-2515, 2009 | 209 | 2009 |
Regulation of lipogenesis by glucocorticoids and insulin in human adipose tissue LL Gathercole, SA Morgan, IJ Bujalska, D Hauton, PM Stewart, ... PloS one 6 (10), e26223, 2011 | 193 | 2011 |
A novel selective 11β-hydroxysteroid dehydrogenase type 1 inhibitor prevents human adipogenesis IJ Bujalska, LL Gathercole, JW Tomlinson, C Darimont, J Ermolieff, ... The Journal of endocrinology 197 (2), 297, 2008 | 115 | 2008 |
Targeting the pre-receptor metabolism of cortisol as a novel therapy in obesity and diabetes LL Gathercole, PM Stewart The Journal of steroid biochemistry and molecular biology 122 (1-3), 21-27, 2010 | 111 | 2010 |
Glucocorticoid modulation of insulin signaling in human subcutaneous adipose tissue LL Gathercole, IJ Bujalska, PM Stewart, JW Tomlinson The Journal of Clinical Endocrinology & Metabolism 92 (11), 4332-4339, 2007 | 103 | 2007 |
Lack of significant metabolic abnormalities in mice with liver-specific disruption of 11β-hydroxysteroid dehydrogenase type 1 GG Lavery, AE Zielinska, LL Gathercole, B Hughes, N Semjonous, ... Endocrinology 153 (7), 3236-3248, 2012 | 84 | 2012 |
Glucocorticoids fail to cause insulin resistance in human subcutaneous adipose tissue in vivo JM Hazlehurst, LL Gathercole, M Nasiri, MJ Armstrong, S Borrows, J Yu, ... The Journal of Clinical Endocrinology & Metabolism 98 (4), 1631-1640, 2013 | 74 | 2013 |
AKR1D1 is a novel regulator of metabolic phenotype in human hepatocytes and is dysregulated in non-alcoholic fatty liver disease N Nikolaou, LL Gathercole, L Marchand, S Althari, NJ Dempster, ... Metabolism 99, 67-80, 2019 | 72 | 2019 |
Effect of insulin on AKR1C3 expression in female adipose tissue: in-vivo and in-vitro study of adipose androgen generation in polycystic ovary syndrome M O'Reilly, L Gathercole, F Capper, W Arlt, J Tomlinson The Lancet 385, S16, 2015 | 67 | 2015 |
Dehydroepiandrosterone exerts antiglucocorticoid action on human preadipocyte proliferation, differentiation, and glucose uptake JC McNelis, KN Manolopoulos, LL Gathercole, IJ Bujalska, PM Stewart, ... American Journal of Physiology-Endocrinology and Metabolism 305 (9), E1134-E1144, 2013 | 67 | 2013 |
5α-Reductase type 2 regulates glucocorticoid action and metabolic phenotype in human hepatocytes M Nasiri, N Nikolaou, S Parajes, NP Krone, G Valsamakis, G Mastorakos, ... Endocrinology 156 (8), 2863-2871, 2015 | 53 | 2015 |
Tissue specific regulation of glucocorticoids in severe obesity and the response to significant weight loss following bariatric surgery (BARICORT) CP Woods, M Corrigan, L Gathercole, A Taylor, B Hughes, G Gaoatswe, ... The Journal of Clinical Endocrinology & Metabolism 100 (4), 1434-1444, 2015 | 52 | 2015 |
Adipocyte differentiation, mitochondrial gene expression and fat distribution: differences between zidovudine and tenofovir after 6 months M Boothby, KC McGee, JW Tomlinson, LL Gathercole, PG McTernan, ... Antiviral Therapy 14 (8), 1089-1100, 2009 | 45 | 2009 |
Regulation of lipid metabolism by glucocorticoids and 11β-HSD1 in skeletal muscle SA Morgan, LL Gathercole, C Simonet, ZK Hassan-Smith, I Bujalska, ... Endocrinology 154 (7), 2374-2384, 2013 | 39 | 2013 |
Hormonal regulation of lipogenesis LL Gathercole, SA Morgan, JW Tomlinson Vitamins & hormones 91, 1-27, 2013 | 38 | 2013 |
Advanced non‐alcoholic fatty liver disease and adipose tissue fibrosis in patients with Alström syndrome LL Gathercole, JM Hazlehurst, MJ Armstrong, R Crowley, S Boocock, ... Liver International 36 (11), 1704-1712, 2016 | 35 | 2016 |
The Role of 11ß-Hydroxysteroid Dehydrogenase 1 in Adipogenesis in Thyroid-Associated Ophthalmopathy JW Tomlinson, OM Durrani, IJ Bujalska, LL Gathercole, PJ Tomlins, ... The Journal of Clinical Endocrinology & Metabolism 95 (1), 398-406, 2010 | 33 | 2010 |