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Laura Nocka
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Autoinhibition of Bruton's tyrosine kinase (Btk) and activation by soluble inositol hexakisphosphate
Q Wang, EM Vogan, LM Nocka, CE Rosen, JA Zorn, SC Harrison, ...
Elife 4, e06074, 2015
1162015
The Src module: an ancient scaffold in the evolution of cytoplasmic tyrosine kinases
NH Shah, JF Amacher, LM Nocka, J Kuriyan
Critical reviews in biochemistry and molecular biology 53 (5), 535-563, 2018
842018
Coupled membrane lipid miscibility and phosphotyrosine-driven protein condensation phase transitions
JK Chung, WYC Huang, CB Carbone, LM Nocka, AN Parikh, RD Vale, ...
Biophysical journal 120 (7), 1257-1265, 2021
532021
A two-component protein condensate of the EGFR cytoplasmic tail and Grb2 regulates Ras activation by SOS at the membrane
CW Lin, LM Nocka, BL Stinger, JB DeGrandchamp, LJN Lew, S Alvarez, ...
Proceedings of the National Academy of Sciences 119 (19), e2122531119, 2022
492022
Switch-like activation of Bruton’s tyrosine kinase by membrane-mediated dimerization
JK Chung, LM Nocka, A Decker, Q Wang, TA Kadlecek, A Weiss, ...
Proceedings of the National Academy of Sciences 116 (22), 10798-10803, 2019
482019
Holliday junction thermodynamics and structure: Coarse-grained simulations and experiments
W Wang, LM Nocka, BZ Wiemann, DM Hinckley, I Mukerji, FW Starr
Scientific reports 6 (1), 22863, 2016
322016
A saturation-mutagenesis analysis of the interplay between stability and activation in Ras
F Hidalgo, LM Nocka, NH Shah, K Gorday, NR Latorraca, P Bandaru, ...
Elife 11, e76595, 2022
192022
Probing the ion binding site in a DNA Holliday junction using Förster resonance energy transfer (FRET)
JL Litke, Y Li, LM Nocka, I Mukerji
International journal of molecular sciences 17 (3), 366, 2016
142016
Stimulation of the catalytic activity of the tyrosine kinase Btk by the adaptor protein Grb2
LM Nocka, TJ Eisen, AT Iavarone, JT Groves, J Kuriyan
Elife 12, e82676, 2023
72023
A two-component protein condensate of EGFR and Grb2 regulates Ras activation at the membrane
CW Lin, LM Nocka, B Stinger, J DeGrandchamp, N Lew, S Alvarez, ...
BioRxiv, 2021.12. 12.472247, 2021
32021
Switch-like activation of Bruton’s tyrosine kinase by membrane-mediated dimerization
JK Chung, LM Nocka, Q Wang, TA Kadlecek, A Weiss, J Kuriyan, ...
BioRxiv, 284000, 2018
22018
Holliday junction thermodynamics and structure: comparisons of coarse-grained simulations and experiments
FW Starr, W Wang, LM Nocka, BZ Wiemann, DM Hinckley, I Mukerji
Biophysical Journal 110 (3), 178a, 2016
12016
Structure and function of Holliday junctions complexed with ions and HU protein
LM Nocka, I Mukerji, D Beveridge, L Wheatley
Biophysical Journal 104 (2), 75a, 2013
12013
Kinetics of the LAT: Grb2: SOS Protein Condensation Phase Transition on Membranes Resemble a Glass Transition
S Sun, TG Pre, LJN Lew, LM Nocka, DT Limmer, JT Groves
Biophysical Journal 120 (3), 328a, 2021
2021
Structural and mechanistic studies of membrane associated signaling proteins
LM Nocka
UC Berkeley, 2021
2021
Coupling between lipid miscibility and phosphotyrosine driven protein condensation at the membrane
JK Chung, WYC Huang, CB Carbone, LM Nocka, AN Parikh, RD Vale, ...
bioRxiv, 2020.07. 22.215970, 2020
2020
Bruton's Tyrosine Kinase Membrane Dynamics and Signaling
LM Nocka, JK Chung, A Decker, T Kadlecek, A Weiss, J Kuriyan, ...
Biophysical Journal 118 (3), 560a-561a, 2020
2020
Measuring Membrane Surface Reactions by Diffusion: Dimerization of Btk PH Domain and K-Ras
JK Chung, LM Nocka, YK Lee, J Kuriyan, JT Groves
Biophysical Journal 114 (3), 558a, 2018
2018
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Articles 1–18