| Abrogating mitochondrial dynamics in mouse hearts accelerates mitochondrial senescence M Song, A Franco, JA Fleischer, L Zhang, GW Dorn Cell metabolism 26 (6), 872-883. e5, 2017 | 279 | 2017 |
| MFN2 agonists reverse mitochondrial defects in preclinical models of Charcot-Marie-Tooth disease type 2A AG Rocha, A Franco, AM Krezel, JM Rumsey, JM Alberti, WC Knight, ... Science 360 (6386), 336-341, 2018 | 256 | 2018 |
| Correcting mitochondrial fusion by manipulating mitofusin conformations A Franco, RN Kitsis, JA Fleischer, E Gavathiotis, OS Kornfeld, G Gong, ... Nature 540 (7631), 74-79, 2016 | 246 | 2016 |
| Restoring mitofusin balance prevents axonal degeneration in a Charcot-Marie-Tooth type 2A model Y Zhou, S Carmona, A Muhammad, S Bell, J Landeros, M Vazquez, R Ho, ... The Journal of clinical investigation 129 (4), 1756-1771, 2019 | 101 | 2019 |
| Targeting the CaMKII/ERK interaction in the heart prevents cardiac hypertrophy E Cipolletta, MR Rusciano, AS Maione, G Santulli, D Sorriento, ... PLoS One 10 (6), e0130477, 2015 | 71 | 2015 |
| Integrating GRK2 and NFkappaB in the pathophysiology of cardiac hypertrophy D Sorriento, G Santulli, A Franco, E Cipolletta, L Napolitano, ... Journal of cardiovascular translational research 8, 493-502, 2015 | 54 | 2015 |
| Burst mitofusin activation reverses neuromuscular dysfunction in murine CMT2A A Franco, X Dang, EK Walton, JN Ho, B Zablocka, C Ly, TM Miller, ... elife 9, e61119, 2020 | 53 | 2020 |
| Endothelial G Protein–Coupled Receptor Kinase 2 Regulates Vascular Homeostasis Through the Control of Free Radical Oxygen Species M Ciccarelli, D Sorriento, A Franco, A Fusco, C Del Giudice, R Annunziata, ... Arteriosclerosis, thrombosis, and vascular biology 33 (10), 2415-2424, 2013 | 38 | 2013 |
| GRK2 moderates the acute mitochondrial damage to ionizing radiation exposure by promoting mitochondrial fission/fusion A Franco, D Sorriento, J Gambardella, R Pacelli, N Prevete, C Procaccini, ... Cell Death Discovery 4 (1), 25, 2018 | 36 | 2018 |
| The tethering function of mitofusin2 controls osteoclast differentiation by modulating the Ca2+–NFATc1 axis A Ballard, R Zeng, A Zarei, C Shao, L Cox, H Yan, A Franco, GW Dorn II, ... Journal of Biological Chemistry 295 (19), 6629-6640, 2020 | 35 | 2020 |
| Discovery of 6-phenylhexanamide derivatives as potent stereoselective mitofusin activators for the treatment of mitochondrial diseases X Dang, L Zhang, A Franco, J Li, AG Rocha, S Devanathan, RE Dolle, ... Journal of medicinal chemistry 63 (13), 7033-7051, 2020 | 33 | 2020 |
| Reciprocal regulation of mitofusin 2-mediated mitophagy and mitochondrial fusion by different PINK1 phosphorylation events J Li, X Dang, A Franco, GW Dorn Frontiers in Cell and Developmental Biology 10, 868465, 2022 | 25 | 2022 |
| Pharmacological inhibition of GRK2 improves cardiac metabolism and function in experimental heart failure M Ciccarelli, D Sorriento, A Fiordelisi, J Gambardella, A Franco, ... ESC Heart Failure 7 (4), 1571-1584, 2020 | 24 | 2020 |
| Dual role of GRK5 in cancer development and progression J Gambardella, A Franco, C Del Giudice, A Fiordelisi, E Cipolletta, ... Translational Medicine@ UniSa 14, 28, 2016 | 24 | 2016 |
| Rays sting: the acute cellular effects of ionizing radiation exposure A Franco, M Ciccarelli, D Sorriento, L Napolitano, A Fiordelisi, B Trimarco, ... Translational Medicine@ UniSa 14, 42, 2016 | 24 | 2016 |
| Mitochondrial dysfunction and pharmacodynamics of mitofusin activation in murine Charcot-Marie-Tooth disease type 2A A Franco, X Dang, L Zhang, PB Molinoff, GW Dorn II The Journal of Pharmacology and Experimental Therapeutics 383 (2), 137-148, 2022 | 13 | 2022 |
| Pharmacophore-based design of phenyl-[hydroxycyclohexyl] cycloalkyl-carboxamide mitofusin activators with improved neuronal activity X Dang, SB Williams, S Devanathan, A Franco, L Fu, PR Bernstein, ... Journal of medicinal chemistry 64 (17), 12506-12524, 2021 | 11 | 2021 |
| Piperine Derivatives Enhance Fusion and Axonal Transport of Mitochondria by Activating Mitofusins Z Lihong, D Xiawei, F Antonietta, Z ,Haiyang, GW Dorn II | 9 | 2022 |
| G-protein receptor kinases 2, 5 and 6 redundantly modulate Smoothened-GATA transcriptional crosstalk in fetal mouse hearts A Franco, L Zhang, SJ Matkovich, A Kovacs, GW Dorn II Journal of molecular and cellular cardiology 121, 60-68, 2018 | 9 | 2018 |
| A human mitofusin 2 mutation can cause mitophagic cardiomyopathy A Franco, J Li, DP Kelly, RE Hershberger, AJ Marian, RM Lewis, M Song, ... Elife 12, e84235, 2023 | 8 | 2023 |
