| Mild and regioselective oxidative bromination of anilines using potassium bromide and sodium perborate D Roche, K Prasad, O Repic, TJ Blacklock Tetrahedron Letters 41 (13), 2083-2085, 2000 | 106 | 2000 |
| Rhodium (iii)-catalyzed allylic C–H bond amination. Synthesis of cyclic amines from ω-unsaturated N-sulfonylamines T Cochet, V Bellosta, D Roche, JY Ortholand, A Greiner, J Cossy Chemical Communications 48 (87), 10745-10747, 2012 | 97 | 2012 |
| Exploring new targets and chemical space with affinity selection-mass spectrometry R Prudent, DA Annis, PJ Dandliker, JY Ortholand, D Roche Nature Reviews Chemistry 5 (1), 62-71, 2021 | 87 | 2021 |
| Isoform-selective ATAD2 chemical probe with novel chemical structure and unusual mode of action AE Fernández-Montalván, M Berger, B Kuropka, SJ Koo, V Badock, ... ACS chemical biology 12 (11), 2730-2736, 2017 | 83 | 2017 |
| Enantioselective acylation of β-aminoesters using penicillin G acylase in organic solvents D Roche, K Prasad, O Repic Tetrahedron letters 40 (19), 3665-3668, 1999 | 68 | 1999 |
| The metabolic sensors FXRα, PGC‐1 α, and SIRT1 cooperatively regulate hepatitis B virus transcription C Curtil, LS Enache, P Radreau, AG Dron, C Scholtès, A Deloire, ... The FASEB Journal 28 (3), 1454-1463, 2014 | 60 | 2014 |
| Total syntheses of bengamides B and E FR Kinder, S Wattanasin, RW Versace, KW Bair, J Bontempo, MA Green, ... The Journal of organic chemistry 66 (6), 2118-2122, 2001 | 46 | 2001 |
| N-Formylsaccharin: a new formylating agent T Cochet, V Bellosta, A Greiner, D Roche, J Cossy Synlett 2011 (13), 1920-1922, 2011 | 43 | 2011 |
| Design, synthesis and decoration of molecular scaffolds for exploitation in the production of alkaloid-like libraries P Craven, A Aimon, M Dow, N Fleury-Bregeot, R Guilleux, R Morgentin, ... Bioorganic & Medicinal Chemistry 23 (11), 2629-2635, 2015 | 41 | 2015 |
| Discovery of novel Cyclophilin D inhibitors starting from three dimensional fragments with millimolar potencies U Grädler, D Schwarz, M Blaesse, B Leuthner, TL Johnson, F Bernard, ... Bioorganic & Medicinal Chemistry Letters 29 (23), 126717, 2019 | 39 | 2019 |
| Methods and pharmaceutical compositions for the treatment of hepatitis B virus infection P Andre, V Lotteau, P Radreau, M Gilardone, A Patin, D Roche, D Cravo, ... US Patent 9,895,380, 2018 | 37 | 2018 |
| Effect of a Phosphazene Base on the Diastereoselectivity of Addition of α-Sulfonyl Carbanions to Butyraldehyde and Isopropylideneglyceraldehyde A Solladié-Cavallo, D Roche, J Fischer, A De Cian The Journal of Organic Chemistry 61 (8), 2690-2694, 1996 | 36 | 1996 |
| Synthesis of sp3-rich scaffolds for molecular libraries through complexity-generating cascade reactions T Flagstad, G Min, K Bonnet, R Morgentin, D Roche, MH Clausen, ... Organic & Biomolecular Chemistry 14 (21), 4943-4946, 2016 | 35 | 2016 |
| An improved procedure of the Pechmann condensation in the synthesis of 8-ethyltrimethoxy-6H-benzo [d] naphtho [1, 2-b] pyran-6-ones structurally related to the aglycon of … DH Hua, S Saha, D Roche, JC Maeng, S Iguchi, C Baldwin The Journal of Organic Chemistry 57 (1), 399-403, 1992 | 32 | 1992 |
| 1, 4-Diazepane-2-ones as novel inhibitors of LFA-1 S Wattanasin, R Albert, C Ehrhardt, D Roche, M Sabio, U Hommel, ... Bioorganic & medicinal chemistry letters 13 (3), 499-502, 2003 | 31 | 2003 |
| Discovery and structure-guided drug design of inhibitors of 11β-hydroxysteroid-dehydrogenase type I based on a spiro-carboxamide scaffold F Lepifre, S Christmann-Franck, D Roche, C Leriche, D Carniato, ... Bioorganic & medicinal chemistry letters 19 (13), 3682-3685, 2009 | 29 | 2009 |
| Discovery and structure–activity relationships of pentanedioic acid diamides as potent inhibitors of 11β-hydroxysteroid dehydrogenase type I D Roche, D Carniato, C Leriche, F Lepifre, S Christmann-Franck, ... Bioorganic & medicinal chemistry letters 19 (10), 2674-2678, 2009 | 23 | 2009 |
| Synthesis and biological properties of macrolactam analogs of the natural product macrolide (−)-A26771B S Canova, R Lépine, A Thys, A Baron, D Roche Bioorganic & medicinal chemistry letters 21 (16), 4768-4772, 2011 | 22 | 2011 |
| Efficient, mild, parallel and purification-free synthesis of aryl ethers via the Mitsunobu reaction E Valeur, D Roche Tetrahedron Letters 49 (26), 4182-4185, 2008 | 20 | 2008 |
| Structure–Activity Relationship in the Leucettine Family of Kinase Inhibitors T Tahtouh, E Durieu, B Villiers, C Bruyère, TL Nguyen, X Fant, KH Ahn, ... Journal of medicinal chemistry 65 (2), 1396-1417, 2021 | 18 | 2021 |
