sFRP2 in the aged microenvironment drives melanoma metastasis and therapy resistance A Kaur, MR Webster, K Marchbank, R Behera, A Ndoye, CH Kugel, ... Nature 532 (7598), 250-254, 2016 | 390 | 2016 |
The epigenetic modifier EZH2 controls melanoma growth and metastasis through silencing of distinct tumour suppressors D Zingg, J Debbache, SM Schaefer, E Tuncer, SC Frommel, P Cheng, ... Nature communications 6 (1), 6051, 2015 | 355 | 2015 |
Germinal centers determine the prognostic relevance of tertiary lymphoid structures and are impaired by corticosteroids in lung squamous cell carcinoma K Siliņa, A Soltermann, FM Attar, R Casanova, ZM Uckeley, H Thut, ... Cancer research 78 (5), 1308-1320, 2018 | 347 | 2018 |
Systematic classification of melanoma cells by phenotype‐specific gene expression mapping DS Widmer, PF Cheng, OM Eichhoff, BC Belloni, MC Zipser, NC Schlegel, ... Pigment cell & melanoma research 25 (3), 343-353, 2012 | 203 | 2012 |
Proteomic analysis of human mesenchymal stromal cell secretomes: a systematic comparison of the angiogenic potential D Kehl, M Generali, A Mallone, M Heller, AC Uldry, P Cheng, ... NPJ Regenerative medicine 4 (1), 8, 2019 | 191 | 2019 |
Hypoxia contributes to melanoma heterogeneity by triggering HIF1α-dependent phenotype switching DS Widmer, KS Hoek, PF Cheng, OM Eichhoff, T Biedermann, ... Journal of Investigative Dermatology 133 (10), 2436-2443, 2013 | 175 | 2013 |
Small molecule promotes β-catenin citrullination and inhibits Wnt signaling in cancer Y Qu, JR Olsen, X Yuan, PF Cheng, MP Levesque, KA Brokstad, ... Nature chemical biology 14 (1), 94-101, 2018 | 135 | 2018 |
Peripheral blood TCR repertoire profiling may facilitate patient stratification for immunotherapy against melanoma SA Hogan, A Courtier, PF Cheng, NF Jaberg-Bentele, SM Goldinger, ... Cancer immunology research 7 (1), 77-85, 2019 | 132 | 2019 |
EZH2-mediated primary cilium deconstruction drives metastatic melanoma formation D Zingg, J Debbache, R Peña-Hernández, AT Antunes, SM Schaefer, ... Cancer cell 34 (1), 69-84. e14, 2018 | 130 | 2018 |
Hedgehog pathway inhibitors promote adaptive immune responses in basal cell carcinoma A Otsuka, J Dreier, PF Cheng, M Nägeli, H Lehmann, L Felderer, IJ Frew, ... Clinical Cancer Research 21 (6), 1289-1297, 2015 | 120 | 2015 |
Methylation-dependent SOX9 expression mediates invasion in human melanoma cells and is a negative prognostic factor in advanced melanoma PF Cheng, O Shakhova, DS Widmer, OM Eichhoff, D Zingg, SC Frommel, ... Genome biology 16, 1-16, 2015 | 116 | 2015 |
Antagonistic cross-regulation between Sox9 and Sox10 controls an anti-tumorigenic program in melanoma O Shakhova, P Cheng, PJ Mishra, D Zingg, SM Schaefer, J Debbache, ... PLoS genetics 11 (1), e1004877, 2015 | 108 | 2015 |
The low affinity neurotrophin receptor CD271 regulates phenotype switching in melanoma G Restivo, J Diener, PF Cheng, G Kiowski, M Bonalli, T Biedermann, ... Nature communications 8 (1), 1988, 2017 | 106* | 2017 |
CARD14 gain-of-function mutation alone is sufficient to drive IL-23/IL-17–mediated psoriasiform skin inflammation in vivo M Mellett, B Meier, D Mohanan, R Schairer, P Cheng, TK Satoh, B Kiefer, ... Journal of investigative dermatology 138 (9), 2010-2023, 2018 | 100 | 2018 |
The ALPK1/TIFA/NF-κB axis links a bacterial carcinogen to R-loop-induced replication stress M Bauer, Z Nascakova, AI Mihai, PF Cheng, MP Levesque, S Lampart, ... Nature communications 11 (1), 5117, 2020 | 95 | 2020 |
Co-existence of BRAF and NRAS driver mutations in the same melanoma cells results in heterogeneity of targeted therapy resistance MIG Raaijmakers, DS Widmer, A Narechania, O Eichhoff, SN Freiberger, ... Oncotarget 7 (47), 77163, 2016 | 93 | 2016 |
Wnt-signaling enhances neural crest migration of melanoma cells and induces an invasive phenotype T Sinnberg, MP Levesque, J Krochmann, PF Cheng, K Ikenberg, ... Molecular cancer 17, 1-19, 2018 | 84 | 2018 |
The EMT transcription factor ZEB2 promotes proliferation of primary and metastatic melanoma while suppressing an invasive, mesenchymal-like phenotype N Vandamme, G Denecker, K Bruneel, G Blancke, Ö Akay, J Taminau, ... Cancer research 80 (14), 2983-2995, 2020 | 77 | 2020 |
Melanoma immunotherapy: next-generation biomarkers SA Hogan, MP Levesque, PF Cheng Frontiers in oncology 8, 178, 2018 | 72 | 2018 |
Data mining The Cancer Genome Atlas in the era of precision cancer medicine PF Cheng, R Dummer, MP Levesque Swiss medical weekly 145 (3738), w14183-w14183, 2015 | 71 | 2015 |