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Jan Miljkovic
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H2S and NO cooperatively regulate vascular tone by activating a neuroendocrine HNO–TRPA1–CGRP signalling pathway
M Eberhardt, M Dux, B Namer, J Miljkovic, N Cordasic, C Will, TI Kichko, ...
Nature communications 5 (1), 4381, 2014
3832014
Chemical Characterization of the Smallest S-Nitrosothiol, HSNO; Cellular Cross-talk of H2S and S-Nitrosothiols
MR Filipovic, JL Miljkovic, T Nauser, M Royzen, K Klos, T Shubina, ...
Journal of the American Chemical Society 134 (29), 12016-12027, 2012
3642012
Selective persulfide detection reveals evolutionarily conserved antiaging effects of S-sulfhydration
J Zivanovic, E Kouroussis, JB Kohl, B Adhikari, B Bursac, S Schott-Roux, ...
Cell metabolism 30 (6), 1152-1170. e13, 2019
3142019
Improved tag-switch method reveals that thioredoxin acts as depersulfidase and controls the intracellular levels of protein persulfidation
R Wedmann, C Onderka, S Wei, IA Szijártó, JL Miljkovic, A Mitrovic, ...
Chemical Science 7 (5), 3414-3426, 2016
2082016
Generation of HNO and HSNO from Nitrite by Heme‐Iron‐Catalyzed Metabolism with H2S
JL Miljkovic, I Kenkel, I Ivanović‐Burmazović, MR Filipovic
Angewandte Chemie International Edition 52 (46), 12061-12064, 2013
1362013
Biochemical insight into physiological effects of H2S: reaction with peroxynitrite and formation of a new nitric oxide donor, sulfinyl nitrite
MR Filipovic, J Miljkovic, A Allgäuer, R Chaurio, T Shubina, M Herrmann, ...
Biochemical Journal 441 (2), 609-621, 2012
1222012
Working with “H2S”: facts and apparent artifacts
R Wedmann, S Bertlein, I Macinkovic, S Böltz, JL Miljkovic, LE Muñoz, ...
Nitric Oxide 41, 85-96, 2014
1192014
Cytochrome c Reduction by H2S Potentiates Sulfide Signaling
V Vitvitsky, JL Miljkovic, T Bostelaar, B Adhikari, PK Yadav, AK Steiger, ...
ACS chemical biology 13 (8), 2300-2307, 2018
952018
Disruption of the TCA cycle reveals an ATF4-dependent integration of redox and amino acid metabolism
DG Ryan, M Yang, HA Prag, GR Blanco, E Nikitopoulou, ...
Elife 10, e72593, 2021
872021
Nitric oxide is reduced to HNO by proton-coupled nucleophilic attack by ascorbate, tyrosine, and other alcohols. A new route to HNO in biological media?
SA Suarez, NI Neuman, M Muñoz, L Álvarez, DE Bikiel, CD Brondino, ...
Journal of the American Chemical Society 137 (14), 4720-4727, 2015
862015
Cystathionine γ-Lyase–Produced hydrogen sulfide controls endothelial no bioavailability and blood pressure
IA Szijártó, L Markó, MR Filipovic, JL Miljkovic, C Tabeling, D Tsvetkov, ...
Hypertension 71 (6), 1210-1217, 2018
702018
Overexpression of cystathionine γ-lyase suppresses detrimental effects of spinocerebellar ataxia type 3
PM Snijder, M Baratashvili, NA Grzeschik, HGD Leuvenink, L Kuijpers, ...
Molecular Medicine 21, 758-768, 2015
482015
Selective persulfide detection reveals evolutionarily conserved antiaging effects of S-sulfhydration
J Zivanovic, E Kouroussis, JB Kohl, B Adhikari, B Bursac, S Schott-Roux, ...
Cell metabolism 31 (1), 207, 2020
362020
Spatiotemporal regulation of hydrogen sulfide signaling in the kidney
M Roorda, JL Miljkovic, H van Goor, RH Henning, HR Bouma
Redox biology 43, 101961, 2021
332021
Amphiphilic pentaazamacrocyclic manganese superoxide dismutase mimetics
D Lieb, I Kenkell, JL Miljkovic, D Moldenhauer, N Weber, MR Filipovic, ...
Inorganic Chemistry 53 (2), 1009-1020, 2014
272014
Rapid and selective generation of H2S within mitochondria protects against cardiac ischemia-reperfusion injury
JL Miljkovic, N Burger, JM Gawel, JF Mulvey, AAI Norman, T Nishimura, ...
Redox Biology 55, 102429, 2022
222022
Naked mole-rats have distinctive cardiometabolic and genetic adaptations to their underground low-oxygen lifestyles
CG Faulkes, TR Eykyn, JL Miljkovic, JD Gilbert, RL Charles, HA Prag, ...
Nature Communications 15 (1), 2204, 2024
102024
Protein thiol alterations drive aberrant phase separation in aging
T Vignane, M Hugo, C Hoffmann, A Katsouda, J Petric, H Wang, M Miler, ...
bioRxiv, 2023.11. 07.566021, 2023
62023
H2S Generates HNO and HSNO from nitrite by a heme iron-catalyzed metabolism in mitochondria
J Miljkovic, I Ivanovic-Burmazovic, M Filipovic
Free Radical Biology and Medicine, S98, 2013
42013
HNO/Thiol Biology as a Therapeutic Target
JL Miljkovic, MR Filipovic
Redox-Active Therapeutics, 335-375, 2016
32016
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