Receptor recognition by the novel coronavirus from Wuhan: an analysis based on decade-long structural studies of SARS coronavirus Y Wan, J Shang, R Graham, RS Baric, F Li Journal of virology 94 (7), 10.1128/jvi. 00127-20, 2020 | 5710 | 2020 |
Broad-spectrum antiviral GS-5734 inhibits both epidemic and zoonotic coronaviruses TP Sheahan, AC Sims, RL Graham, VD Menachery, LE Gralinski, ... Science translational medicine 9 (396), eaal3653, 2017 | 1928 | 2017 |
Coronavirus susceptibility to the antiviral remdesivir (GS-5734) is mediated by the viral polymerase and the proofreading exoribonuclease ML Agostini, EL Andres, AC Sims, RL Graham, TP Sheahan, X Lu, ... MBio 9 (2), 10.1128/mbio. 00221-18, 2018 | 1441 | 2018 |
A SARS-like cluster of circulating bat coronaviruses shows potential for human emergence VD Menachery, BL Yount, K Debbink, S Agnihothram, LE Gralinski, ... Nature medicine 21 (12), 1508-1513, 2015 | 1258 | 2015 |
An orally bioavailable broad-spectrum antiviral inhibits SARS-CoV-2 in human airway epithelial cell cultures and multiple coronaviruses in mice TP Sheahan, AC Sims, S Zhou, RL Graham, AJ Pruijssers, ML Agostini, ... Science translational medicine 12 (541), eabb5883, 2020 | 1145 | 2020 |
SARS-CoV-2 D614G variant exhibits efficient replication ex vivo and transmission in vivo YJ Hou, S Chiba, P Halfmann, C Ehre, M Kuroda, KH Dinnon III, SR Leist, ... Science 370 (6523), 1464-1468, 2020 | 977 | 2020 |
A decade after SARS: strategies for controlling emerging coronaviruses RL Graham, EF Donaldson, RS Baric Nature Reviews Microbiology 11 (12), 836-848, 2013 | 926 | 2013 |
Recombination, reservoirs, and the modular spike: mechanisms of coronavirus cross-species transmission RL Graham, RS Baric Journal of virology 84 (7), 3134-3146, 2010 | 868 | 2010 |
Coronaviruses: an RNA proofreading machine regulates replication fidelity and diversity MR Denison, RL Graham, EF Donaldson, LD Eckerle, RS Baric RNA biology 8 (2), 270-279, 2011 | 593 | 2011 |
Broad spectrum antiviral remdesivir inhibits human endemic and zoonotic deltacoronaviruses with a highly divergent RNA dependent RNA polymerase AJ Brown, JJ Won, RL Graham, KH Dinnon III, AC Sims, JY Feng, T Cihlar, ... Antiviral research 169, 104541, 2019 | 590 | 2019 |
Infidelity of SARS-CoV Nsp14-exonuclease mutant virus replication is revealed by complete genome sequencing LD Eckerle, MM Becker, RA Halpin, K Li, E Venter, X Lu, S Scherbakova, ... PLoS pathogens 6 (5), e1000896, 2010 | 532 | 2010 |
Remdesivir inhibits SARS-CoV-2 in human lung cells and chimeric SARS-CoV expressing the SARS-CoV-2 RNA polymerase in mice AJ Pruijssers, AS George, A Schäfer, SR Leist, LE Gralinksi, KH Dinnon, ... Cell reports 32 (3), 2020 | 525 | 2020 |
SARS-like WIV1-CoV poised for human emergence VD Menachery, BL Yount Jr, AC Sims, K Debbink, SS Agnihothram, ... Proceedings of the National Academy of Sciences 113 (11), 3048-3053, 2016 | 492 | 2016 |
Synthetic recombinant bat SARS-like coronavirus is infectious in cultured cells and in mice MM Becker, RL Graham, EF Donaldson, B Rockx, AC Sims, T Sheahan, ... Proceedings of the National Academy of Sciences 105 (50), 19944-19949, 2008 | 333 | 2008 |
Reverse genetics with a full-length infectious cDNA of the Middle East respiratory syndrome coronavirus T Scobey, BL Yount, AC Sims, EF Donaldson, SS Agnihothram, ... Proceedings of the National Academy of Sciences 110 (40), 16157-16162, 2013 | 332 | 2013 |
Cell host response to infection with novel human coronavirus EMC predicts potential antivirals and important differences with SARS coronavirus L Josset, VD Menachery, LE Gralinski, S Agnihothram, P Sova, VS Carter, ... MBio 4 (3), 10.1128/mbio. 00165-13, 2013 | 300 | 2013 |
Identification of human neutralizing antibodies against MERS-CoV and their role in virus adaptive evolution XC Tang, SS Agnihothram, Y Jiao, J Stanhope, RL Graham, EC Peterson, ... Proceedings of the National Academy of Sciences 111 (19), E2018-E2026, 2014 | 290 | 2014 |
Baricitinib in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial and updated meta-analysis O Abani, A Abbas, F Abbas, J Abbas, K Abbas, M Abbas, S Abbasi, ... The Lancet 400 (10349), 359-368, 2022 | 288 | 2022 |
A live, impaired-fidelity coronavirus vaccine protects in an aged, immunocompromised mouse model of lethal disease RL Graham, MM Becker, LD Eckerle, M Bolles, MR Denison, RS Baric Nature medicine 18 (12), 1820-1826, 2012 | 259 | 2012 |
The nsp2 replicase proteins of murine hepatitis virus and severe acute respiratory syndrome coronavirus are dispensable for viral replication RL Graham, AC Sims, SM Brockway, RS Baric, MR Denison Journal of virology 79 (21), 13399-13411, 2005 | 257 | 2005 |