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Rachel Graham
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Receptor recognition by the novel coronavirus from Wuhan: an analysis based on decade-long structural studies of SARS coronavirus
Y Wan, J Shang, R Graham, RS Baric, F Li
Journal of virology 94 (7), 10.1128/jvi. 00127-20, 2020
57102020
Broad-spectrum antiviral GS-5734 inhibits both epidemic and zoonotic coronaviruses
TP Sheahan, AC Sims, RL Graham, VD Menachery, LE Gralinski, ...
Science translational medicine 9 (396), eaal3653, 2017
19282017
Coronavirus susceptibility to the antiviral remdesivir (GS-5734) is mediated by the viral polymerase and the proofreading exoribonuclease
ML Agostini, EL Andres, AC Sims, RL Graham, TP Sheahan, X Lu, ...
MBio 9 (2), 10.1128/mbio. 00221-18, 2018
14412018
A SARS-like cluster of circulating bat coronaviruses shows potential for human emergence
VD Menachery, BL Yount, K Debbink, S Agnihothram, LE Gralinski, ...
Nature medicine 21 (12), 1508-1513, 2015
12582015
An orally bioavailable broad-spectrum antiviral inhibits SARS-CoV-2 in human airway epithelial cell cultures and multiple coronaviruses in mice
TP Sheahan, AC Sims, S Zhou, RL Graham, AJ Pruijssers, ML Agostini, ...
Science translational medicine 12 (541), eabb5883, 2020
11452020
SARS-CoV-2 D614G variant exhibits efficient replication ex vivo and transmission in vivo
YJ Hou, S Chiba, P Halfmann, C Ehre, M Kuroda, KH Dinnon III, SR Leist, ...
Science 370 (6523), 1464-1468, 2020
9772020
A decade after SARS: strategies for controlling emerging coronaviruses
RL Graham, EF Donaldson, RS Baric
Nature Reviews Microbiology 11 (12), 836-848, 2013
9262013
Recombination, reservoirs, and the modular spike: mechanisms of coronavirus cross-species transmission
RL Graham, RS Baric
Journal of virology 84 (7), 3134-3146, 2010
8682010
Coronaviruses: an RNA proofreading machine regulates replication fidelity and diversity
MR Denison, RL Graham, EF Donaldson, LD Eckerle, RS Baric
RNA biology 8 (2), 270-279, 2011
5932011
Broad spectrum antiviral remdesivir inhibits human endemic and zoonotic deltacoronaviruses with a highly divergent RNA dependent RNA polymerase
AJ Brown, JJ Won, RL Graham, KH Dinnon III, AC Sims, JY Feng, T Cihlar, ...
Antiviral research 169, 104541, 2019
5902019
Infidelity of SARS-CoV Nsp14-exonuclease mutant virus replication is revealed by complete genome sequencing
LD Eckerle, MM Becker, RA Halpin, K Li, E Venter, X Lu, S Scherbakova, ...
PLoS pathogens 6 (5), e1000896, 2010
5322010
Remdesivir inhibits SARS-CoV-2 in human lung cells and chimeric SARS-CoV expressing the SARS-CoV-2 RNA polymerase in mice
AJ Pruijssers, AS George, A Schäfer, SR Leist, LE Gralinksi, KH Dinnon, ...
Cell reports 32 (3), 2020
5252020
SARS-like WIV1-CoV poised for human emergence
VD Menachery, BL Yount Jr, AC Sims, K Debbink, SS Agnihothram, ...
Proceedings of the National Academy of Sciences 113 (11), 3048-3053, 2016
4922016
Synthetic recombinant bat SARS-like coronavirus is infectious in cultured cells and in mice
MM Becker, RL Graham, EF Donaldson, B Rockx, AC Sims, T Sheahan, ...
Proceedings of the National Academy of Sciences 105 (50), 19944-19949, 2008
3332008
Reverse genetics with a full-length infectious cDNA of the Middle East respiratory syndrome coronavirus
T Scobey, BL Yount, AC Sims, EF Donaldson, SS Agnihothram, ...
Proceedings of the National Academy of Sciences 110 (40), 16157-16162, 2013
3322013
Cell host response to infection with novel human coronavirus EMC predicts potential antivirals and important differences with SARS coronavirus
L Josset, VD Menachery, LE Gralinski, S Agnihothram, P Sova, VS Carter, ...
MBio 4 (3), 10.1128/mbio. 00165-13, 2013
3002013
Identification of human neutralizing antibodies against MERS-CoV and their role in virus adaptive evolution
XC Tang, SS Agnihothram, Y Jiao, J Stanhope, RL Graham, EC Peterson, ...
Proceedings of the National Academy of Sciences 111 (19), E2018-E2026, 2014
2902014
Baricitinib in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial and updated meta-analysis
O Abani, A Abbas, F Abbas, J Abbas, K Abbas, M Abbas, S Abbasi, ...
The Lancet 400 (10349), 359-368, 2022
2882022
A live, impaired-fidelity coronavirus vaccine protects in an aged, immunocompromised mouse model of lethal disease
RL Graham, MM Becker, LD Eckerle, M Bolles, MR Denison, RS Baric
Nature medicine 18 (12), 1820-1826, 2012
2592012
The nsp2 replicase proteins of murine hepatitis virus and severe acute respiratory syndrome coronavirus are dispensable for viral replication
RL Graham, AC Sims, SM Brockway, RS Baric, MR Denison
Journal of virology 79 (21), 13399-13411, 2005
2572005
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Articles 1–20