Anchoring of intratumorally administered cytokines to collagen safely potentiates systemic cancer immunotherapy N Momin, NK Mehta, NR Bennett, L Ma, JR Palmeri, MM Chinn, EA Lutz, ... Science translational medicine 11 (498), eaaw2614, 2019 | 203 | 2019 |
Maximizing response to intratumoral immunotherapy in mice by tuning local retention N Momin, JR Palmeri, EA Lutz, N Jailkhani, H Mak, A Tabet, MM Chinn, ... Nature Communications 13 (1), 109, 2022 | 66 | 2022 |
Alum-anchored intratumoral retention improves the tolerability and antitumor efficacy of type I interferon therapies EA Lutz, Y Agarwal, N Momin, SC Cowles, JR Palmeri, E Duong, V Hornet, ... Proceedings of the National Academy of Sciences 119 (36), e2205983119, 2022 | 26 | 2022 |
Both intratumoral regulatory T cell depletion and CTLA-4 antagonism are required for maximum efficacy of anti-CTLA-4 antibodies BM Lax, JR Palmeri, EA Lutz, A Sheen, JA Stinson, L Duhamel, ... Proceedings of the National Academy of Sciences 120 (31), e2300895120, 2023 | 18 | 2023 |
Tumor-localized catalases can fail to alter tumor growth or transcriptional profiles in subcutaneous syngeneic mouse tumor models A Sheen, Y Agarwal, KM Cheah, SC Cowles, JA Stinson, JR Palmeri, ... Redox Biology, 102766, 2023 | 10 | 2023 |
An affinity threshold for maximum efficacy in anti-PD-1 immunotherapy SC Cowles, A Sheen, L Santollani, EA Lutz, BM Lax, JR Palmeri, ... Mabs 14 (1), 2088454, 2022 | 8 | 2022 |
Local delivery of cell surface-targeted immunocytokines programs systemic anti-tumor immunity L Santollani, YJ Zhang, L Maiorino, JR Palmeri, JA Stinson, LR Duhamel, ... bioRxiv, 2024.01. 03.573641, 2024 | 2 | 2024 |
Tregs constrain CD8+ T cell priming required for curative intratumorally anchored anti-4-1BB immunotherapy JR Palmeri, BM Lax, JM Peters, L Duhamel, JA Stinson, L Santollani, ... Biorxiv, 2023 | 2 | 2023 |
Collagen-localized immunomodulatory molecules and methods thereof KD Wittrup, N Momin, J Palmeri, M Chinn US Patent App. 18/056,825, 2023 | | 2023 |
Collagen Anchoring Agonist Antibodies for Cancer Immunotherapy JR Palmeri Massachusetts Institute of Technology, 2023 | | 2023 |
Collagen-localized immunomodulatory molecules and methods thereof KD Wittrup, N Momin, J Palmeri, M Chinn US Patent App. 16/523,965, 2020 | | 2020 |
Collagen anchoring of intratumorally administered agonist antibodies improves efficacy and limits toxicities J Palmeri, K Wittrup JOURNAL FOR IMMUNOTHERAPY OF CANCER 7, 2019 | | 2019 |