| Enzymes with extra talents: moonlighting functions and catalytic promiscuity SD Copley Current opinion in chemical biology 7 (2), 265-272, 2003 | 648 | 2003 |
| Evolution of a metabolic pathway for degradation of a toxic xenobiotic: the patchwork approach SD Copley Trends in Biochemical Sciences 25 (6), 261-265, 2000 | 277 | 2000 |
| The conformational equilibrium of chorismate in solution: implications for the mechanism of the non-enzymic and the enzyme-catalyzed rearrangement of chorismate to prephenate SD Copley, JR Knowles Journal of the American Chemical Society 109 (16), 5008-5013, 1987 | 250 | 1987 |
| Evolution of efficient pathways for degradation of anthropogenic chemicals SD Copley Nature chemical biology 5 (8), 559-566, 2009 | 247 | 2009 |
| Moonlighting is mainstream: paradigm adjustment required SD Copley Bioessays 34 (7), 578-588, 2012 | 235 | 2012 |
| Genome Shuffling Improves Degradation of the Anthropogenic Pesticide Pentachlorophenol by Sphingobium chlorophenolicum ATCC 39723 MH Dai, SD Copley Applied and environmental microbiology 70 (4), 2391-2397, 2004 | 232 | 2004 |
| Lateral gene transfer and parallel evolution in the history of glutathione biosynthesis genes SD Copley, JK Dhillon Genome biology 3, 1-16, 2002 | 212 | 2002 |
| The origin of the RNA world: co-evolution of genes and metabolism SD Copley, E Smith, HJ Morowitz Bioorganic chemistry 35 (6), 430-443, 2007 | 207 | 2007 |
| Shining a light on enzyme promiscuity SD Copley Current opinion in structural biology 47, 167-175, 2017 | 188 | 2017 |
| An evolutionary biochemist's perspective on promiscuity SD Copley Trends in biochemical sciences 40 (2), 72-78, 2015 | 185 | 2015 |
| Divergence of function in the thioredoxin fold suprafamily: evidence for evolution of peroxiredoxins from a thioredoxin-like ancestor SD Copley, WRP Novak, PC Babbitt Biochemistry 43 (44), 13981-13995, 2004 | 185 | 2004 |
| A mechanism for the association of amino acids with their codons and the origin of the genetic code SD Copley, E Smith, HJ Morowitz Proceedings of the National Academy of Sciences 102 (12), 4442-4447, 2005 | 140 | 2005 |
| Three serendipitous pathways in E. coli can bypass a block in pyridoxal‐5′‐phosphate synthesis J Kim, JP Kershner, Y Novikov, RK Shoemaker, SD Copley Molecular systems biology 6 (1), 436, 2010 | 138 | 2010 |
| Recruitment of a double bond isomerase to serve as a reductive dehalogenase during biodegradation of pentachlorophenol K Anandarajah, PM Kiefer, BS Donohoe, SD Copley Biochemistry 39 (18), 5303-5311, 2000 | 137 | 2000 |
| The mechanism of the chorismate mutase reaction WJ Guilford, SD Copley, JR Knowles Journal of the American Chemical Society 109 (16), 5013-5019, 1987 | 131 | 1987 |
| Evolution of new enzymes by gene duplication and divergence SD Copley The FEBS journal 287 (7), 1262-1283, 2020 | 113 | 2020 |
| The uncatalyzed Claisen rearrangement of chorismate to prephenate prefers a transition state of chair-like geometry SD Copley, JR Knowles Journal Of The American Chemical Society 107 (18), 5306-5308, 1985 | 113 | 1985 |
| Microbial dehalogenases: enzymes recruited to convert xenobiotic substrates SD Copley Current opinion in chemical biology 2 (5), 613-617, 1998 | 108 | 1998 |
| The possibility of alternative microbial life on Earth CE Cleland, SD Copley International Journal of Astrobiology 4 (3-4), 165-173, 2005 | 107 | 2005 |
| Evidence that pcpA encodes 2, 6-dichlorohydroquinone dioxygenase, the ring cleavage enzyme required for pentachlorophenol degradation in Sphingomonas chlorophenolica strain … L Xu, K Resing, SL Lawson, PC Babbitt, SD Copley Biochemistry 38 (24), 7659-7669, 1999 | 107 | 1999 |
