APOE4 impairs the microglial response in Alzheimer’s disease by inducing TGFβ-mediated checkpoints Z Yin, N Rosenzweig, KL Kleemann, X Zhang, W Brandão, MA Margeta, ... Nature immunology 24 (11), 1839-1853, 2023 | 81 | 2023 |
Apolipoprotein E4 impairs the response of neurodegenerative retinal microglia and prevents neuronal loss in glaucoma MA Margeta, Z Yin, C Madore, KM Pitts, SM Letcher, J Tang, S Jiang, ... Immunity 55 (9), 1627-1644. e7, 2022 | 62 | 2022 |
Identification of a protective microglial state mediated by miR-155 and interferon-γ signaling in a mouse model of Alzheimer’s disease Z Yin, S Herron, S Silveira, K Kleemann, C Gauthier, D Mallah, Y Cheng, ... Nature neuroscience 26 (7), 1196-1207, 2023 | 57 | 2023 |
Regulating microglial miR-155 transcriptional phenotype alleviates Alzheimer’s-induced retinal vasculopathy by limiting Clec7a/Galectin-3+ neurodegenerative … H Shi, Z Yin, Y Koronyo, DT Fuchs, J Sheyn, MR Davis, JW Wilson, ... Acta neuropathologica communications 10 (1), 136, 2022 | 26 | 2022 |
Neurodegeneration markers galectin-3 and apolipoprotein E are elevated in the aqueous humor of eyes with glaucoma KM Pitts, CE Neeson, NE Hall, JB Lin, HK Falah, SL Wang, KT Lo, ... Translational Vision Science & Technology 11 (11), 1-1, 2022 | 9 | 2022 |
Neurofilament light chain in aqueous humor as a marker of neurodegeneration in glaucoma JB Lin, KM Pitts, H El Helwe, C Neeson, NE Hall, H Falah, SA Schultz, ... Clinical Ophthalmology, 2209-2217, 2023 | 4 | 2023 |
Myeloid masquerade: Microglial transcriptional signatures in retinal development and disease KM Pitts, MA Margeta Frontiers in Cellular Neuroscience 17, 1106547, 2023 | 4 | 2023 |
Peripheral nerve development in zebrafish requires muscle patterning by tcf15/paraxis LE Limbach, RL Penick, RS Casseday, MA Hyland, EA Pontillo, AN Ayele, ... Developmental biology 490, 37-49, 2022 | 3 | 2022 |
Steroid response following dropless cataract surgery using subconjunctival triamcinolone AM Wu, KM Pitts, R Pineda, SH Chen, M Wang, G Johnson, LQ Shen, ... Clinical Ophthalmology, 2803-2814, 2023 | 2 | 2023 |
Inhaled xenon modulates microglia and ameliorates disease in mouse models of amyloidosis and tauopathy W Brandao, N Jain, Z Yin, KL Kleemann, M Carpenter, X Bao, JR Serrano, ... Science Translational Medicine 17 (781), eadk3690, 2025 | | 2025 |
Epigenetic adaptation drives monocyte differentiation into microglia-like cells upon engraftment into the retina J Liu, F Lei, B Yan, N Cui, J Sharma, V Correa, L Roach, S Nicolaou, ... bioRxiv, 2024 | | 2024 |
Monocytes undergo transcriptional and biochemical changes, allowing expression of microglia markers P2ry12, TMEM119, FCRLS and Iba1 upon engraftment into the retina. J Liu, F Lei, N Cui, B Yan, J Sharma, VSMC Correa, S Nicolaou, K Pitts, ... Investigative Ophthalmology & Visual Science 65 (7), 1688-1688, 2024 | | 2024 |
Deletion of miR‐155 in microglia enhances their response to neurodegeneration and mitigates cognitive impairment in a mouse model of Alzheimer’s disease Z Yin, S Herron, S Silveira, K Kleemann, C Gauthier, D Mallah, C Cheng, ... Alzheimer's & Dementia 19, e076703, 2023 | | 2023 |
APOE4 impairs Microglia‐Astrocyte Crosstalk in Alzheimer Disease K Kleemann, N Rosenzweig, Z Yin, X Zhang, WN Brandao, M Margeta, ... Alzheimer's & Dementia 19, e071852, 2023 | | 2023 |
APOE4 impairs microglia‐astrocyte response in Alzheimer’s disease by inducing TGFβ‐mediated checkpoints O Butovsky, Z Yin, N Rosenzweig, K Kleemann, X Zhang, WN Brandao, ... Alzheimer's & Dementia 19, e076510, 2023 | | 2023 |
Suppressing ApoE ε4 allele protects against signs of Alzheimer’s disease Z Yin, N Rosenzweig, KL Kleemann, X Zhang, W Brandão, MA Margeta, ... | | 2023 |
Aqueous Humor Neurofilament Light Chain is a Marker of Neurodegeneration in Glaucoma JB Lin, K Pitts, C Neeson, NE Hall, H Falah, H El Helwe, S Wang, K Lo, ... Investigative Ophthalmology & Visual Science 64 (8), 1009-1009, 2023 | | 2023 |
APOE4 MICROGLIAL RESPONSE TO NEURODEGENERATION HAS AN OPPOSITE EFFECT IN ALZHEIMER’S DISEASE AND GLAUCOMA O Butovsky, Z Yin, N Rosenzweig, M Margeta, C Madore, WN Brandao, ... Alzheimer's Association International Conference, 2022 | | 2022 |
APOE and Galectin-3, markers of activated microglia, are elevated in the aqueous humor of glaucoma patients K Pitts, C Neeson, N Hall, H Falah, M Margeta, D Solá-Del Valle Investigative Ophthalmology & Visual Science 63 (7), 928–A0397-928–A0397, 2022 | | 2022 |
APOE4 impairs the response of neurodegenerative microglia and prevents neuronal loss in glaucoma M Margeta, KM Pitts, O Butovsky Investigative Ophthalmology & Visual Science 63 (7), 11-11, 2022 | | 2022 |