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Kristen Pitts
Kristen Pitts
Washington University School of Medicine
Verified email at wustl.edu
Title
Cited by
Cited by
Year
APOE4 impairs the microglial response in Alzheimer’s disease by inducing TGFβ-mediated checkpoints
Z Yin, N Rosenzweig, KL Kleemann, X Zhang, W Brandão, MA Margeta, ...
Nature immunology 24 (11), 1839-1853, 2023
812023
Apolipoprotein E4 impairs the response of neurodegenerative retinal microglia and prevents neuronal loss in glaucoma
MA Margeta, Z Yin, C Madore, KM Pitts, SM Letcher, J Tang, S Jiang, ...
Immunity 55 (9), 1627-1644. e7, 2022
622022
Identification of a protective microglial state mediated by miR-155 and interferon-γ signaling in a mouse model of Alzheimer’s disease
Z Yin, S Herron, S Silveira, K Kleemann, C Gauthier, D Mallah, Y Cheng, ...
Nature neuroscience 26 (7), 1196-1207, 2023
572023
Regulating microglial miR-155 transcriptional phenotype alleviates Alzheimer’s-induced retinal vasculopathy by limiting Clec7a/Galectin-3+ neurodegenerative …
H Shi, Z Yin, Y Koronyo, DT Fuchs, J Sheyn, MR Davis, JW Wilson, ...
Acta neuropathologica communications 10 (1), 136, 2022
262022
Neurodegeneration markers galectin-3 and apolipoprotein E are elevated in the aqueous humor of eyes with glaucoma
KM Pitts, CE Neeson, NE Hall, JB Lin, HK Falah, SL Wang, KT Lo, ...
Translational Vision Science & Technology 11 (11), 1-1, 2022
92022
Neurofilament light chain in aqueous humor as a marker of neurodegeneration in glaucoma
JB Lin, KM Pitts, H El Helwe, C Neeson, NE Hall, H Falah, SA Schultz, ...
Clinical Ophthalmology, 2209-2217, 2023
42023
Myeloid masquerade: Microglial transcriptional signatures in retinal development and disease
KM Pitts, MA Margeta
Frontiers in Cellular Neuroscience 17, 1106547, 2023
42023
Peripheral nerve development in zebrafish requires muscle patterning by tcf15/paraxis
LE Limbach, RL Penick, RS Casseday, MA Hyland, EA Pontillo, AN Ayele, ...
Developmental biology 490, 37-49, 2022
32022
Steroid response following dropless cataract surgery using subconjunctival triamcinolone
AM Wu, KM Pitts, R Pineda, SH Chen, M Wang, G Johnson, LQ Shen, ...
Clinical Ophthalmology, 2803-2814, 2023
22023
Inhaled xenon modulates microglia and ameliorates disease in mouse models of amyloidosis and tauopathy
W Brandao, N Jain, Z Yin, KL Kleemann, M Carpenter, X Bao, JR Serrano, ...
Science Translational Medicine 17 (781), eadk3690, 2025
2025
Epigenetic adaptation drives monocyte differentiation into microglia-like cells upon engraftment into the retina
J Liu, F Lei, B Yan, N Cui, J Sharma, V Correa, L Roach, S Nicolaou, ...
bioRxiv, 2024
2024
Monocytes undergo transcriptional and biochemical changes, allowing expression of microglia markers P2ry12, TMEM119, FCRLS and Iba1 upon engraftment into the retina.
J Liu, F Lei, N Cui, B Yan, J Sharma, VSMC Correa, S Nicolaou, K Pitts, ...
Investigative Ophthalmology & Visual Science 65 (7), 1688-1688, 2024
2024
Deletion of miR‐155 in microglia enhances their response to neurodegeneration and mitigates cognitive impairment in a mouse model of Alzheimer’s disease
Z Yin, S Herron, S Silveira, K Kleemann, C Gauthier, D Mallah, C Cheng, ...
Alzheimer's & Dementia 19, e076703, 2023
2023
APOE4 impairs Microglia‐Astrocyte Crosstalk in Alzheimer Disease
K Kleemann, N Rosenzweig, Z Yin, X Zhang, WN Brandao, M Margeta, ...
Alzheimer's & Dementia 19, e071852, 2023
2023
APOE4 impairs microglia‐astrocyte response in Alzheimer’s disease by inducing TGFβ‐mediated checkpoints
O Butovsky, Z Yin, N Rosenzweig, K Kleemann, X Zhang, WN Brandao, ...
Alzheimer's & Dementia 19, e076510, 2023
2023
Suppressing ApoE ε4 allele protects against signs of Alzheimer’s disease
Z Yin, N Rosenzweig, KL Kleemann, X Zhang, W Brandão, MA Margeta, ...
2023
Aqueous Humor Neurofilament Light Chain is a Marker of Neurodegeneration in Glaucoma
JB Lin, K Pitts, C Neeson, NE Hall, H Falah, H El Helwe, S Wang, K Lo, ...
Investigative Ophthalmology & Visual Science 64 (8), 1009-1009, 2023
2023
APOE4 MICROGLIAL RESPONSE TO NEURODEGENERATION HAS AN OPPOSITE EFFECT IN ALZHEIMER’S DISEASE AND GLAUCOMA
O Butovsky, Z Yin, N Rosenzweig, M Margeta, C Madore, WN Brandao, ...
Alzheimer's Association International Conference, 2022
2022
APOE and Galectin-3, markers of activated microglia, are elevated in the aqueous humor of glaucoma patients
K Pitts, C Neeson, N Hall, H Falah, M Margeta, D Solá-Del Valle
Investigative Ophthalmology & Visual Science 63 (7), 928–A0397-928–A0397, 2022
2022
APOE4 impairs the response of neurodegenerative microglia and prevents neuronal loss in glaucoma
M Margeta, KM Pitts, O Butovsky
Investigative Ophthalmology & Visual Science 63 (7), 11-11, 2022
2022
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