| The mechanisms of Hedgehog signalling and its roles in development and disease J Briscoe, PP Thérond Nature reviews Molecular cell biology 14 (7), 416-429, 2013 | 1979 | 2013 |
| Hedgehog elicits signal transduction by means of a large complex containing the kinesin-related protein costal2 DJ Robbins, KE Nybakken, R Kobayashi, JC Sisson, JM Bishop, ... Cell 90 (2), 225-234, 1997 | 458 | 1997 |
| Stability and association of Smoothened, Costal2 and Fused with Cubitus interruptus are regulated by Hedgehog L Ruel, R Rodriguez, A Gallet, L Lavenant-Staccini, PP Thérond Nature cell biology 5 (10), 907-913, 2003 | 244 | 2003 |
| Cholesterol modification of hedgehog is required for trafficking and movement, revealing an asymmetric cellular response to hedgehog A Gallet, R Rodriguez, L Ruel, PP Therond Developmental cell 4 (2), 191-204, 2003 | 217 | 2003 |
| Cellular trafficking of the glypican Dally-like is required for full-strength Hedgehog signaling and wingless transcytosis A Gallet, L Staccini-Lavenant, PP Thérond Developmental cell 14 (5), 712-725, 2008 | 197 | 2008 |
| A putative serine/threonine protein kinase encoded by the segment-polarity fused gene of Drosophila T Préat, P Thérond, C Lamour-Lsnard, B Limbourg-Bouchon, H Tricoire, ... Nature 347 (6288), 87-89, 1990 | 197 | 1990 |
| Cholesterol modification is necessary for controlled planar long-range activity of Hedgehog in Drosophila epithelia A Gallet, L Ruel, L Staccini-Lavenant, PP Thérond Oxford University Press for The Company of Biologists Limited 133 (3), 407-418, 2006 | 176 | 2006 |
| The ESCRT machinery regulates the secretion and long-range activity of Hedgehog T Matusek, F Wendler, S Polès, S Pizette, G D’angelo, M Fürthauer, ... Nature 516 (7529), 99-103, 2014 | 171 | 2014 |
| Evaluating Smoothened as a G-protein-coupled receptor for Hedgehog signalling KL Ayers, PP Thérond Trends in cell biology 20 (5), 287-298, 2010 | 144 | 2010 |
| Phosphorylation of the fused protein kinase in response to signaling from hedgehog. PP Thérond, JD Knight, TB Kornberg, JM Bishop Proceedings of the National Academy of Sciences 93 (9), 4224-4228, 1996 | 144 | 1996 |
| Heart tube patterning in Drosophila requires integration of axial and segmental information provided by the Bithorax Complex genes and hedgehog signaling R Ponzielli, M Astier, A Chartier, A Gallet, P Thérond, M Sémériva Oxford University Press for The Company of Biologists Limited 129 (19), 4509 …, 2002 | 134 | 2002 |
| The long-range activity of Hedgehog is regulated in the apical extracellular space by the glypican Dally and the hydrolase Notum KL Ayers, A Gallet, L Staccini-Lavenant, PP Thérond Developmental cell 18 (4), 605-620, 2010 | 126 | 2010 |
| The Suppressor of fused gene encodes a novel PEST protein involved in Drosophila segment polarity establishment. A Pham, P Therond, G Alves, FB Tournier, D Busson, C Lamour-Isnard, ... Genetics 140 (2), 587-598, 1995 | 110 | 1995 |
| Segmental polarity in Drosophila melanogaster: genetic dissection of fused in a Suppressor of fused background reveals interaction with costal-2. T Préat, P Thérond, B Limbourg-Bouchon, A Pham, H Tricoire, D Busson, ... Genetics 135 (4), 1047-1062, 1993 | 109 | 1993 |
| Analysis of the hypoxia-sensing pathway in Drosophila melanogaster N Arquier, P Vigne, E Duplan, T Hsu, PP Therond, C Frelin, G d'Angelo Biochemical Journal 393 (2), 471-480, 2006 | 81 | 2006 |
| Hedgehog signaling: from the Drosophila cuticle to anti-cancer drugs J Briscoe, P Thérond Developmental Cell 8 (2), 143-151, 2005 | 81 | 2005 |
| Temporal modulation of the Hedgehog morphogen gradient by a patched-dependent targeting to lysosomal compartment A Gallet, PP Therond Developmental biology 277 (1), 51-62, 2005 | 76 | 2005 |
| Phosphorylation of the atypical kinesin Costal2 by the kinase Fused induces the partial disassembly of the Smoothened-Fused-Costal2-Cubitus interruptus complex in Hedgehog … L Ruel, A Gallet, S Raisin, A Truchi, L Staccini-Lavenant, A Cervantes, ... Oxford University Press for The Company of Biologists Limited 134 (20), 3677 …, 2007 | 72 | 2007 |
| The role of kinases in the Hedgehog signalling pathway RA Aikin, KL Ayers, PP Thérond EMBO reports 9 (4), 330-336, 2008 | 71 | 2008 |
| Functional domains of fused, a serine-threonine kinase required for signaling in Drosophila P Thérond, G Alves, B Limbourg-Bouchon, H Tricoire, E Guillemet, ... Genetics 142 (4), 1181-1198, 1996 | 66 | 1996 |