Protein–Sol: a web tool for predicting protein solubility from sequence M Hebditch, MA Carballo-Amador, S Charonis, R Curtis, J Warwicker Bioinformatics 33 (19), 3098-3100, 2017 | 605 | 2017 |
Protein‐protein and protein‐salt interactions in aqueous protein solutions containing concentrated electrolytes RA Curtis, JM Prausnitz, HW Blanch Biotechnology and bioengineering 57 (1), 11-21, 1998 | 307 | 1998 |
Protein–protein interactions in concentrated electrolyte solutions RA Curtis, J Ulrich, A Montaser, JM Prausnitz, HW Blanch Biotechnology and bioengineering 79 (4), 367-380, 2002 | 270 | 2002 |
A molecular approach to bioseparations: protein–protein and protein–salt interactions RA Curtis, L Lue Chemical Engineering Science 61 (3), 907-923, 2006 | 234 | 2006 |
The role of electrostatics in protein–protein interactions of a monoclonal antibody D Roberts, R Keeling, M Tracka, CF Van Der Walle, S Uddin, J Warwicker, ... Molecular pharmaceutics 11 (7), 2475-2489, 2014 | 182 | 2014 |
Specific ion and buffer effects on protein–protein interactions of a monoclonal antibody D Roberts, R Keeling, M Tracka, CF Van Der Walle, S Uddin, J Warwicker, ... Molecular pharmaceutics 12 (1), 179-193, 2015 | 176 | 2015 |
Interaction between hydrophobic surfaces with metastable intervening liquid D Bratko, RA Curtis, HW Blanch, JM Prausnitz The Journal of Chemical Physics 115 (8), 3873-3877, 2001 | 132 | 2001 |
Protein—protein interactions in aqueous ammonium sulfate solutions. Lysozyme and bovine serum albumin (BSA) YU Moon, RA Curtis, CO Anderson, HW Blanch, JM Prausnitz Journal of Solution Chemistry 29, 699-718, 2000 | 126 | 2000 |
Acceleration of crystal growth rates: an unexpected effect of tailor-made additives R Dowling, RJ Davey, RA Curtis, G Han, SK Poornachary, PS Chow, ... Chemical Communications 46 (32), 5924-5926, 2010 | 116 | 2010 |
Soluble expression of proteins correlates with a lack of positively-charged surface P Chan, RA Curtis, J Warwicker Scientific reports 3 (1), 3333, 2013 | 105 | 2013 |
Hydrophobic forces between protein molecules in aqueous solutions of concentrated electrolyte RA Curtis, C Steinbrecher, M Heinemann, HW Blanch, JM Prausnitz Biophysical chemistry 98 (3), 249-265, 2002 | 92 | 2002 |
Lysine and arginine content of proteins: computational analysis suggests a new tool for solubility design J Warwicker, S Charonis, RA Curtis Molecular pharmaceutics 11 (1), 294-303, 2014 | 87 | 2014 |
Calculation of phase diagrams for aqueous protein solutions RA Curtis, HW Blanch, JM Prausnitz The Journal of Physical Chemistry B 105 (12), 2445-2452, 2001 | 83 | 2001 |
Production of recombinant peptides as fusions with SUMO M Satakarni, R Curtis Protein expression and purification 78 (2), 113-119, 2011 | 81 | 2011 |
Current advances in biopharmaceutical informatics: guidelines, impact and challenges in the computational developability assessment of antibody therapeutics R Khetan, R Curtis, CM Deane, JT Hadsund, U Kar, K Krawczyk, ... MAbs 14 (1), 2020082, 2022 | 69 | 2022 |
The crystal structure of the FAD/NADPH‐binding domain of flavocytochrome P450 BM3 MG Joyce, IS Ekanem, O Roitel, AJ Dunford, R Neeli, HM Girvan, ... The FEBS journal 279 (9), 1694-1706, 2012 | 68 | 2012 |
The effect of charge mutations on the stability and aggregation of a human single chain Fv fragment JI Austerberry, R Dajani, S Panova, D Roberts, AP Golovanov, A Pluen, ... European Journal of Pharmaceutics and Biopharmaceutics 115, 18-30, 2017 | 61 | 2017 |
Flavocytochrome P450 BM3 mutant W1046A is a NADH-dependent fatty acid hydroxylase: implications for the mechanism of electron transfer in the P450 BM3 dimer HM Girvan, AJ Dunford, R Neeli, IS Ekanem, TN Waltham, MG Joyce, ... Archives of biochemistry and biophysics 507 (1), 75-85, 2011 | 54 | 2011 |
Osmolyte effects on monoclonal antibody stability and concentration-dependent protein interactions with water and common osmolytes GV Barnett, VI Razinkov, BA Kerwin, S Blake, W Qi, RA Curtis, CJ Roberts The Journal of Physical Chemistry B 120 (13), 3318-3330, 2016 | 50 | 2016 |
Advancing therapeutic protein discovery and development through comprehensive computational and biophysical characterization L Gentiluomo, HL Svilenov, D Augustijn, I El Bialy, ML Greco, A Kulakova, ... Molecular Pharmaceutics 17 (2), 426-440, 2019 | 49 | 2019 |