| Quantitative proteomics reveals the function of unconventional ubiquitin chains in proteasomal degradation P Xu, DM Duong, NT Seyfried, D Cheng, Y Xie, J Robert, J Rush, ... Cell 137 (1), 133-145, 2009 | 1458 | 2009 |
| ZNRF3 promotes Wnt receptor turnover in an R-spondin-sensitive manner HX Hao, Y Xie, Y Zhang, O Charlat, E Oster, M Avello, H Lei, C Mickanin, ... Nature 485 (7397), 195-200, 2012 | 1048 | 2012 |
| Inactivating mutations of RNF43 confer Wnt dependency in pancreatic ductal adenocarcinoma X Jiang, HX Hao, JD Growney, S Woolfenden, C Bottiglio, N Ng, B Lu, ... Proceedings of the National Academy of Sciences 110 (31), 12649-12654, 2013 | 447 | 2013 |
| The RSPO–LGR4/5–ZNRF3/RNF43 module controls liver zonation and size L Planas-Paz, V Orsini, L Boulter, D Calabrese, M Pikiolek, F Nigsch, ... Nature cell biology 18 (5), 467-479, 2016 | 275 | 2016 |
| The yeast Hex3· Slx8 heterodimer is a ubiquitin ligase stimulated by substrate sumoylation Y Xie, O Kerscher, MB Kroetz, HF McConchie, P Sung, M Hochstrasser Journal of Biological Chemistry 282 (47), 34176-34184, 2007 | 261 | 2007 |
| R-Spondin potentiates Wnt/β-catenin signaling through orphan receptors LGR4 and LGR5 H Ruffner, J Sprunger, O Charlat, J Leighton-Davies, B Grosshans, ... PloS one 7 (7), e40976, 2012 | 217 | 2012 |
| Deubiquitinase FAM/USP9X interacts with the E3 ubiquitin ligase SMURF1 protein and protects it from ligase activity-dependent self-degradation Y Xie, M Avello, M Schirle, E McWhinnie, Y Feng, E Bric-Furlong, ... Journal of Biological Chemistry 288 (5), 2976-2985, 2013 | 135 | 2013 |
| Interaction with both ZNRF3 and LGR4 is required for the signalling activity of R‐spondin Y Xie, R Zamponi, O Charlat, M Ramones, S Swalley, X Jiang, D Rivera, ... EMBO reports 14 (12), 1120-1126, 2013 | 112 | 2013 |
| SUMO-independent in vivo activity of a SUMO-targeted ubiquitin ligase toward a short-lived transcription factor Y Xie, EM Rubenstein, T Matt, M Hochstrasser Genes & development 24 (9), 893-903, 2010 | 107 | 2010 |
| DNA binding by the MATα2 transcription factor controls its access to alternative ubiquitin-modification pathways CM Hickey, Y Xie, M Hochstrasser Molecular Biology of the Cell 29 (5), 542-556, 2018 | 20 | 2018 |
| Antibodies and methods for WNT pathway-related diseases F Cong, H Hao, LB Klickstein, R Kwong, A Taylor, Y Xie US Patent 9,296,826, 2016 | 10 | 2016 |
| Molecular genetics of the ubiquitin-proteasome system: lessons from yeast M Hochstrasser, M Deng, AR Kusmierczyk, X Li, SG Kreft, T Ravid, ... The Ubiquitin System in Health and Disease, 41-66, 2009 | 10 | 2009 |
| Antibodies and methods for wnt pathway-related diseases F Cong, H Hao, LB Klickstein, R Kwong, A Taylor, Y Xie US Patent App. 15/073,156, 2018 | 5 | 2018 |
| R-spondin controls liver zonation and size via Lgr4 and Lgr5 receptors L Planas Paz, V Orsini, D Calabrese, L Boulter, F Nigsch, G Roma, ... R-spondin controls liver zonation and size via Lgr4 and Lgr5 receptors, 0 | | |
Mark HochstrasserYale UniversityVerified email at yale.edu
