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Lin Tan
Lin Tan
Verified email at mdanderson.org
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Year
CD38-mediated immunosuppression as a mechanism of tumor cell escape from PD-1/PD-L1 blockade
L Chen, L Diao, Y Yang, X Yi, BL Rodriguez, Y Li, PA Villalobos, ...
Cancer discovery 8 (9), 1156-1175, 2018
4152018
KAT2A coupled with the α-KGDH complex acts as a histone H3 succinyltransferase
Y Wang, YR Guo, K Liu, Z Yin, R Liu, Y Xia, L Tan, P Yang, JH Lee, X Li, ...
Nature 552 (7684), 273-277, 2017
4152017
Molecular characterization and clinical relevance of metabolic expression subtypes in human cancers
X Peng, Z Chen, F Farshidfar, X Xu, PL Lorenzi, Y Wang, F Cheng, L Tan, ...
Cell reports 23 (1), 255-269. e4, 2018
2682018
PTEN suppresses glycolysis by dephosphorylating and inhibiting autophosphorylated PGK1
X Qian, X Li, Z Shi, Y Xia, Q Cai, D Xu, L Tan, L Du, Y Zheng, D Zhao, ...
Molecular Cell 76 (3), 516-527. e7, 2019
1682019
EGFR-phosphorylated platelet isoform of phosphofructokinase 1 promotes PI3K activation
JH Lee, R Liu, J Li, Y Wang, L Tan, XJ Li, X Qian, C Zhang, Y Xia, D Xu, ...
Molecular cell 70 (2), 197-210. e7, 2018
1602018
Genome-wide identification and differential analysis of translational initiation
P Zhang, D He, Y Xu, J Hou, BF Pan, Y Wang, T Liu, CM Davis, EA Ehli, ...
Nature communications 8 (1), 1749, 2017
1322017
The glutaminase inhibitor CB-839 (telaglenastat) enhances the antimelanoma activity of T-cell–mediated immunotherapies
S Varghese, S Pramanik, LJ Williams, HR Hodges, CW Hudgens, ...
Molecular cancer therapeutics 20 (3), 500-511, 2021
1082021
A sucrose-enriched diet promotes tumorigenesis in mammary gland in part through the 12-lipoxygenase pathway
Y Jiang, Y Pan, PR Rhea, L Tan, M Gagea, L Cohen, SM Fischer, P Yang
Cancer research 76 (1), 24-29, 2016
1062016
Choline kinase alpha 2 acts as a protein kinase to promote lipolysis of lipid droplets
R Liu, JH Lee, J Li, R Yu, L Tan, Y Xia, Y Zheng, XL Bian, PL Lorenzi, ...
Molecular cell 81 (13), 2722-2735. e9, 2021
982021
Targeting MCL-1 dysregulates cell metabolism and leukemia-stroma interactions and re-sensitizes acute myeloid leukemia to BCL-2 inhibition
BZ Carter, PY Mak, W Tao, M Warmoes, PL Lorenzi, D Mak, V Ruvolo, ...
Haematologica 107 (1), 58, 2020
942020
Glutaminase Activity of L-Asparaginase Contributes to Durable Preclinical Activity against Acute Lymphoblastic Leukemia
WK Chan, TD Horvath, L Tan, T Link, KG Harutyunyan, MA Pontikos, ...
Molecular cancer therapeutics 18 (9), 1587-1592, 2019
822019
Conversion of PRPS hexamer to monomer by AMPK-mediated phosphorylation inhibits nucleotide synthesis in response to energy stress
X Qian, X Li, L Tan, JH Lee, Y Xia, Q Cai, Y Zheng, H Wang, PL Lorenzi, ...
Cancer discovery 8 (1), 94-107, 2018
732018
Tumor-resident Lactobacillus iners confer chemoradiation resistance through lactate-induced metabolic rewiring
LE Colbert, MB El Alam, R Wang, T Karpinets, D Lo, EJ Lynn, TA Harris, ...
Cancer Cell 41 (11), 1945-1962. e11, 2023
702023
Mucus-degrading Bacteroides link carbapenems to aggravated graft-versus-host disease
E Hayase, T Hayase, MA Jamal, T Miyama, CC Chang, MR Ortega, ...
Cell 185 (20), 3705-3719. e14, 2022
672022
PBI-05204, a supercritical CO2 extract of Nerium oleander, inhibits growth of human pancreatic cancer via targeting the PI3K/mTOR pathway
Y Pan, P Rhea, L Tan, C Cartwright, HJ Lee, MK Ravoori, C Addington, ...
Investigational New Drugs 33, 271-279, 2015
622015
ATF4 protects the heart from failure by antagonizing oxidative stress
X Wang, G Zhang, S Dasgupta, EL Niewold, C Li, Q Li, X Luo, L Tan, ...
Circulation research 131 (1), 91-105, 2022
582022
Changes in cancer cell metabolism revealed by direct sample analysis with MALDI mass spectrometry
DA Pirman, E Efuet, XP Ding, Y Pan, L Tan, SM Fischer, RN DuBois, ...
PloS one 8 (4), e61379, 2013
452013
Eicosapentaenoic acid in combination with EPHA2 inhibition shows efficacy in preclinical models of triple-negative breast cancer by disrupting cellular cholesterol efflux
AM Torres-Adorno, H Vitrac, Y Qi, L Tan, KR Levental, YY Fan, P Yang, ...
Oncogene 38 (12), 2135-2150, 2019
442019
PKM1 exerts critical roles in cardiac remodeling under pressure overload in the heart
Q Li, C Li, A Elnwasany, G Sharma, YA An, G Zhang, WM Elhelaly, J Lin, ...
Circulation 144 (9), 712-727, 2021
412021
Medium-chain Acyl-CoA dehydrogenase protects mitochondria from lipid peroxidation in glioblastoma
F Puca, F Yu, C Bartolacci, P Pettazzoni, A Carugo, E Huang-Hobbs, J Liu, ...
Cancer discovery 11 (11), 2904-2923, 2021
392021
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