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Bing Bai
Bing Bai
Verified email at ualberta.ca
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Peptidomimetic α-acyloxymethylketone warheads with six-membered lactam P1 glutamine mimic: SARS-CoV-2 3CL protease inhibition, coronavirus antiviral activity, and in vitro …
B Bai, A Belovodskiy, M Hena, AS Kandadai, MA Joyce, HA Saffran, ...
Journal of Medicinal Chemistry 65 (4), 2905-2925, 2021
1002021
Peptidomimetic nitrile warheads as SARS-CoV-2 3CL protease inhibitors
B Bai, E Arutyunova, MB Khan, J Lu, MA Joyce, HA Saffran, JA Shields, ...
RSC medicinal chemistry 12 (10), 1722-1730, 2021
512021
SARS-CoV-2 Mpro Protease Variants of Concern Display Altered Viral Substrate and Cell Host Target Galectin-8 Processing but Retain Sensitivity toward Antivirals
SA Chen, E Arutyunova, J Lu, MB Khan, W Rut, M Zmudzinski, S Shahbaz, ...
ACS Central Science 9 (4), 696-708, 2023
432023
Lipooligosaccharides from mycobacteria: structure, function, and synthesis
B Bai, C Chu, TL Lowary
Israel Journal of Chemistry 55 (3‐4), 360-372, 2015
242015
Design, synthesis and immunological evaluation of novel amphiphilic desmuramyl peptides
FA Khan, M Ulanova, B Bai, D Yalamati, ZH Jiang
European Journal of Medicinal Chemistry 141, 26-36, 2017
162017
Synthesis of a Tridecasaccharide Lipooligosaccharide Antigen from the Opportunistic Pathogen Mycobacterium kansasii
K Shen, B Bai, YH Liu, TL Lowary
Angewandte Chemie International Edition 60 (47), 24859-24863, 2021
82021
The Effect of Deuteration and Homologation of the Lactam Ring of Nirmatrelvir on Its Biochemical Properties and Oxidative Metabolism
E Arutyunova, A Belovodskiy, P Chen, MB Khan, M Joyce, H Saffran, J Lu, ...
ACS Bio & Med Chem Au 3 (6), 528-541, 2023
42023
Synthesis of Lipooligosaccharide Antigens from Mycobacteria
B Bai
22014
Inhibition of the hERG potassium ion channel by different non-nucleoside human cytomegalovirus polymerase antiviral inhibitor series and the exploration of variations on a …
AS Kandadai, B Bai, M Rahim, F Lin, Z Gu, X Qi, X Zhang, H Dong, ...
Bioorganic & Medicinal Chemistry 85, 117276, 2023
12023
Rna virus inhibitor compounds and uses thereof
JA Nieman, MJ Lemieux, DL Tyrrell, B Bai, A Belovodskiy, M Hena, ...
US Patent App. 17/556,700, 2022
12022
Discovery of Novel Pyrido[2,3‐b]Pyrazine Human Cytomegalovirus Polymerase Inhibitors with Broad Spectrum Antiherpetic Activity and Reduced hERG Inhibition
B Bai, A Srinivas Kandadai, M Hena, A Belovodskiy, J Shen, M Houghton, ...
ChemMedChem, e202400629, 2024
2024
Compounds for the Treatment of Alzheimer's Disease
JA Nieman, J Jhamandas, B Bai, A Belovodskiy, W Fu, M Hena, ...
US Patent App. 18/444,006, 2024
2024
Compounds for the treatment of Alzheimer's disease
JA Nieman, J Jhamandas, B Bai, A Belovodskiy, W Fu, M Hena, ...
US Patent 11,939,302, 2024
2024
Rna virus inhibitor compounds with improved metabolic stability and uses thereof
JA Nieman, MJ Lemieux, E Arutyunova, MA Joyce, DL Tyrrell, H Saffran, ...
US Patent App. 18/205,215, 2023
2023
Inhibitors of Human Herpesviruses
J Nieman, M Hena, B Bai, AS Kandadai, A Belovodskiy
US Patent App. 17/800,516, 2023
2023
Non-Peptidic Heterocycle-Containing Compounds for the Treatment of Alzheimer? s Disease
J Jhamandas, W Fu, R Kimura, DL Tyrrell, A Clementin, K Sahu, ...
US Patent App. 17/605,194, 2022
2022
Inhibition of the HERG Potassium Ion Channel by Different Non-Nucleoside Human Cytomegalovirus Polymerase Antiviral Templates and the Exploration of Variations of a …
AS Kandadai, B Bai, M Rahim, F Lin, Z Gu, X Qi, X Zhang, H Dong, ...
Available at SSRN 4352003, 0
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