Peptidomimetic α-acyloxymethylketone warheads with six-membered lactam P1 glutamine mimic: SARS-CoV-2 3CL protease inhibition, coronavirus antiviral activity, and in vitro … B Bai, A Belovodskiy, M Hena, AS Kandadai, MA Joyce, HA Saffran, ... Journal of Medicinal Chemistry 65 (4), 2905-2925, 2021 | 100 | 2021 |
Peptidomimetic nitrile warheads as SARS-CoV-2 3CL protease inhibitors B Bai, E Arutyunova, MB Khan, J Lu, MA Joyce, HA Saffran, JA Shields, ... RSC medicinal chemistry 12 (10), 1722-1730, 2021 | 51 | 2021 |
SARS-CoV-2 Mpro Protease Variants of Concern Display Altered Viral Substrate and Cell Host Target Galectin-8 Processing but Retain Sensitivity toward Antivirals SA Chen, E Arutyunova, J Lu, MB Khan, W Rut, M Zmudzinski, S Shahbaz, ... ACS Central Science 9 (4), 696-708, 2023 | 43 | 2023 |
Lipooligosaccharides from mycobacteria: structure, function, and synthesis B Bai, C Chu, TL Lowary Israel Journal of Chemistry 55 (3‐4), 360-372, 2015 | 24 | 2015 |
Design, synthesis and immunological evaluation of novel amphiphilic desmuramyl peptides FA Khan, M Ulanova, B Bai, D Yalamati, ZH Jiang European Journal of Medicinal Chemistry 141, 26-36, 2017 | 16 | 2017 |
Synthesis of a Tridecasaccharide Lipooligosaccharide Antigen from the Opportunistic Pathogen Mycobacterium kansasii K Shen, B Bai, YH Liu, TL Lowary Angewandte Chemie International Edition 60 (47), 24859-24863, 2021 | 8 | 2021 |
The Effect of Deuteration and Homologation of the Lactam Ring of Nirmatrelvir on Its Biochemical Properties and Oxidative Metabolism E Arutyunova, A Belovodskiy, P Chen, MB Khan, M Joyce, H Saffran, J Lu, ... ACS Bio & Med Chem Au 3 (6), 528-541, 2023 | 4 | 2023 |
Synthesis of Lipooligosaccharide Antigens from Mycobacteria B Bai | 2 | 2014 |
Inhibition of the hERG potassium ion channel by different non-nucleoside human cytomegalovirus polymerase antiviral inhibitor series and the exploration of variations on a … AS Kandadai, B Bai, M Rahim, F Lin, Z Gu, X Qi, X Zhang, H Dong, ... Bioorganic & Medicinal Chemistry 85, 117276, 2023 | 1 | 2023 |
Rna virus inhibitor compounds and uses thereof JA Nieman, MJ Lemieux, DL Tyrrell, B Bai, A Belovodskiy, M Hena, ... US Patent App. 17/556,700, 2022 | 1 | 2022 |
Discovery of Novel Pyrido[2,3‐b]Pyrazine Human Cytomegalovirus Polymerase Inhibitors with Broad Spectrum Antiherpetic Activity and Reduced hERG Inhibition B Bai, A Srinivas Kandadai, M Hena, A Belovodskiy, J Shen, M Houghton, ... ChemMedChem, e202400629, 2024 | | 2024 |
Compounds for the Treatment of Alzheimer's Disease JA Nieman, J Jhamandas, B Bai, A Belovodskiy, W Fu, M Hena, ... US Patent App. 18/444,006, 2024 | | 2024 |
Compounds for the treatment of Alzheimer's disease JA Nieman, J Jhamandas, B Bai, A Belovodskiy, W Fu, M Hena, ... US Patent 11,939,302, 2024 | | 2024 |
Rna virus inhibitor compounds with improved metabolic stability and uses thereof JA Nieman, MJ Lemieux, E Arutyunova, MA Joyce, DL Tyrrell, H Saffran, ... US Patent App. 18/205,215, 2023 | | 2023 |
Inhibitors of Human Herpesviruses J Nieman, M Hena, B Bai, AS Kandadai, A Belovodskiy US Patent App. 17/800,516, 2023 | | 2023 |
Non-Peptidic Heterocycle-Containing Compounds for the Treatment of Alzheimer? s Disease J Jhamandas, W Fu, R Kimura, DL Tyrrell, A Clementin, K Sahu, ... US Patent App. 17/605,194, 2022 | | 2022 |
Inhibition of the HERG Potassium Ion Channel by Different Non-Nucleoside Human Cytomegalovirus Polymerase Antiviral Templates and the Exploration of Variations of a … AS Kandadai, B Bai, M Rahim, F Lin, Z Gu, X Qi, X Zhang, H Dong, ... Available at SSRN 4352003, 0 | | |