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Amna Ghith
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Design, synthesis and molecular modeling study of certain VEGFR-2 inhibitors based on thienopyrimidne scaffold as cancer targeting agents
A Ghith, KM Youssef, NSM Ismail, KAM Abouzid
Bioorganic Chemistry 83, 111-128, 2019
462019
Medicinal attributes of thienopyrimidine based scaffold targeting tyrosine kinases and their potential anticancer activities
A Ghith, NSM Ismail, K Youssef, KAM Abouzid
Archiv der Pharmazie 350 (11), 1700242, 2017
282017
A comparison of steroid and lipid binding cytochrome P450s from Mycobacterium marinum and Mycobacterium tuberculosis
SA Child, A Ghith, JB Bruning, SG Bell
Journal of Inorganic Biochemistry 209, 111116, 2020
152020
The Structures of the Steroid Binding CYP142 Cytochrome P450 Enzymes from Mycobacterium ulcerans and Mycobacterium marinum
A Ghith, DZ Doherty, JB Bruning, RA Russell, JJ De Voss, SG Bell
ACS Infectious Diseases 8 (8), 1606-1617, 2022
82022
The binding of nitrogen-donor ligands to the ferric and ferrous forms of cytochrome P450 enzymes
H Mohamed, A Ghith, SG Bell
Journal of Inorganic Biochemistry 242, 112168, 2023
72023
The bacterial cytochrome P450 (CYP) CYP125 enzymes can competitively oxidise sitosterol in the presence of cholesterol
DZ Doherty, A Ghith, A Ho, JJ De Voss, SG Bell
Chemical Communications 59 (61), 9392-9395, 2023
42023
The oxidation of cholesterol derivatives by the CYP124 and CYP142 enzymes from Mycobacterium marinum
A Ghith, JB Bruning, SG Bell
The Journal of Steroid Biochemistry and Molecular Biology 231, 106317, 2023
32023
The catalytic activity and structure of the lipid metabolizing CYP124 cytochrome P450 enzyme from Mycobacterium marinum
A Ghith, JB Bruning, SG Bell
Archives of Biochemistry and Biophysics 737, 109554, 2023
32023
The Role of Breastmilk in Macrophage-Tumour Cell Interactions in Postpartum Breast Cancer
R Maleki, A Ghith, H Heydarlou, LE Grzeskowiak, WV Ingman
Frontiers in Bioscience-Landmark 29 (9), 328, 2024
2024
Synthesis of steroidal inhibitors for Mycobacterium tuberculosis
LR Churchman, JR Beckett, L Tan, K Woods, DZ Doherty, A Ghith, ...
The Journal of Steroid Biochemistry and Molecular Biology 239, 106479, 2024
2024
The oxidation of steroid derivatives by the CYP125A6 and CYP125A7 enzymes from Mycobacterium marinum
A Ghith, SG Bell
The Journal of Steroid Biochemistry and Molecular Biology 235, 106406, 2023
2023
Understanding cytochrome P450 cholesterol metabolism in bacteria
AJSM Ghith
2023
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