| Clonal neoantigens elicit T cell immunoreactivity and sensitivity to immune checkpoint blockade N McGranahan, AJS Furness, R Rosenthal, S Ramskov, R Lyngaa, ... Science 351 (6280), 1463-1469, 2016 | 3187 | 2016 |
| Meta-analysis of tumor-and T cell-intrinsic mechanisms of sensitization to checkpoint inhibition K Litchfield, JL Reading, C Puttick, K Thakkar, C Abbosh, R Bentham, ... Cell 184 (3), 596-614. e14, 2021 | 705 | 2021 |
| Large-scale detection of antigen-specific T cells using peptide-MHC-I multimers labeled with DNA barcodes AK Bentzen, AM Marquard, R Lyngaa, SK Saini, S Ramskov, M Donia, ... Nature biotechnology 34 (10), 1037-1045, 2016 | 363 | 2016 |
| SARS-CoV-2 genome-wide T cell epitope mapping reveals immunodominance and substantial CD8+ T cell activation in COVID-19 patients SK Saini, DS Hersby, T Tamhane, HR Povlsen, SPA Hernandez, ... Science immunology 6 (58), eabf7550, 2021 | 230 | 2021 |
| Human endogenous retroviruses and their implication for immunotherapeutics of cancer AS Attermann, AM Bjerregaard, SK Saini, K Grønbæk, SR Hadrup Annals of Oncology 29 (11), 2183-2191, 2018 | 104 | 2018 |
| The T cell differentiation landscape is shaped by tumour mutations in lung cancer E Ghorani, JL Reading, JY Henry, MR Massy, R Rosenthal, V Turati, ... Nature cancer 1 (5), 546-561, 2020 | 96 | 2020 |
| Empty peptide-receptive MHC class I molecules for efficient detection of antigen-specific T cells SK Saini, T Tamhane, R Anjanappa, A Saikia, S Ramskov, M Donia, ... Science immunology 4 (37), eaau9039, 2019 | 94 | 2019 |
| Peptide-independent stabilization of MHC class I molecules breaches cellular quality control Z Hein, H Uchtenhagen, ET Abualrous, SK Saini, L Janßen, ... Journal of cell science 127 (13), 2885-2897, 2014 | 81 | 2014 |
| Human endogenous retroviruses form a reservoir of T cell targets in hematological cancers SK Saini, AD Ørskov, AM Bjerregaard, A Unnikrishnan, ... Nature communications 11 (1), 5660, 2020 | 75 | 2020 |
| Dipeptides promote folding and peptide binding of MHC class I molecules SK Saini, K Ostermeir, VR Ramnarayan, H Schuster, M Zacharias, ... Proceedings of the National Academy of Sciences 110 (38), 15383-15388, 2013 | 75 | 2013 |
| Dipeptides catalyze rapid peptide exchange on MHC class I molecules SK Saini, H Schuster, VR Ramnarayan, HG Rammensee, S Stevanović, ... Proceedings of the National Academy of Sciences 112 (1), 202-207, 2015 | 66 | 2015 |
| Not all empty MHC class I molecules are molten globules: Tryptophan fluorescence reveals a two-step mechanism of thermal denaturation SK Saini, ET Abualrous, AS Tigan, K Covella, U Wellbrock, S Springer Molecular immunology 54 (3-4), 386-396, 2013 | 49 | 2013 |
| The Carboxy Terminus of the Ligand Peptide Determines the Stability of the MHC Class I Molecule H-2Kb: A Combined Molecular Dynamics and Experimental Study ET Abualrous, SK Saini, VR Ramnarayan, FT Ilca, M Zacharias, ... PloS one 10 (8), e0135421, 2015 | 45 | 2015 |
| High throughput epitope identification and t cell receptor specificity determination using loadable detection molecules SR Hadrup, SN Jakobsen, SK Saini US Patent App. 17/279,025, 2023 | 37 | 2023 |
| Novel tools to assist neoepitope targeting in personalized cancer immunotherapy SK Saini, N Rekers, SR Hadrup Annals of Oncology 28, xii3-xii10, 2017 | 36 | 2017 |
| Additive effects of booster mRNA vaccination and SARS-CoV-2 Omicron infection on T cell immunity across immunocompromised states TR Müller, T Sekine, D Trubach, J Niessl, P Chen, P Bergman, O Blennow, ... Science translational medicine 15 (704), eadg9452, 2023 | 22 | 2023 |
| Three doses of BNT162b2 COVID-19 mRNA vaccine establish long-lasting CD8+ T cell immunity in CLL and MDS patients SPA Hernandez, DS Hersby, KK Munk, T Tamhane, D Trubach, ... Frontiers in Immunology 13, 1035344, 2023 | 18 | 2023 |
| Safety, outcomes, and T-cell characteristics in patients with relapsed or refractory MDS or CMML treated with atezolizumab in combination with guadecitabine CL O'Connell, MR Baer, AD Ørskov, SK Saini, VH Duong, P Kropf, ... Clinical Cancer Research 28 (24), 5306-5316, 2022 | 16 | 2022 |
| SARS-CoV-2 genome-wide mapping of CD8 T cell recognition reveals strong immunodominance and substantial CD8 T cell activation in COVID-19 patients SK Saini, DS Hersby, T Tamhane, HR Povlsen, SPA Hernandez, ... Biorxiv, 2020.10. 19.344911, 2020 | 9 | 2020 |
| Neoantigen reactive T cells correlate with the low mutational burden in hematological malignancies SK Saini, S Holmberg-Thydén, AM Bjerregaard, A Unnikrishnan, ... Leukemia 36 (11), 2734-2738, 2022 | 3 | 2022 |
Sebastian SpringerProfessor of Biochemistry and Cell Biology, Constructor UniversityVerified email at constructor.university
