| Tau-mediated neurodegeneration in Alzheimer's disease and related disorders C Ballatore, VMY Lee, JQ Trojanowski Nature reviews neuroscience 8 (9), 663-672, 2007 | 2764 | 2007 |
| Carboxylic acid (bio) isosteres in drug design C Ballatore, DM Huryn, AB Smith III ChemMedChem 8 (3), 385-395, 2013 | 616 | 2013 |
| The microtubule-stabilizing agent, epothilone D, reduces axonal dysfunction, neurotoxicity, cognitive deficits, and Alzheimer-like pathology in an interventional study with … B Zhang, J Carroll, JQ Trojanowski, Y Yao, M Iba, JS Potuzak, ... Journal of Neuroscience 32 (11), 3601-3611, 2012 | 437 | 2012 |
| Epothilone D improves microtubule density, axonal integrity, and cognition in a transgenic mouse model of tauopathy KR Brunden, B Zhang, J Carroll, Y Yao, JS Potuzak, AML Hogan, M Iba, ... Journal of Neuroscience 30 (41), 13861-13866, 2010 | 348 | 2010 |
| Structure property relationships of carboxylic acid isosteres P Lassalas, B Gay, C Lasfargeas, MJ James, V Tran, KG Vijayendran, ... Journal of medicinal chemistry 59 (7), 3183-3203, 2016 | 278 | 2016 |
| Microtubule stabilizing agents as potential treatment for Alzheimer’s disease and related neurodegenerative tauopathies C Ballatore, KR Brunden, DM Huryn, JQ Trojanowski, VMY Lee, ... American Chemical Society, 2012 | 261 | 2012 |
| Targeting heat shock proteins on cancer cells: selection, characterization, and cell-penetrating properties of a peptidic GRP78 ligand Y Kim, AM Lillo, SCJ Steiniger, Y Liu, C Ballatore, A Anichini, R Mortarini, ... Biochemistry 45 (31), 9434-9444, 2006 | 216 | 2006 |
| The characterization of microtubule-stabilizing drugs as possible therapeutic agents for Alzheimer's disease and related tauopathies KR Brunden, Y Yao, JS Potuzak, NI Ferrer, C Ballatore, MJ James, ... Pharmacological research 63 (4), 341-351, 2011 | 197 | 2011 |
| Identification of SARS-CoV-2 inhibitors targeting Mpro and PLpro using in-cell-protease assay A Narayanan, M Narwal, SA Majowicz, C Varricchio, SA Toner, ... Communications Biology 5 (1), 169, 2022 | 191 | 2022 |
| Aminothienopyridazines and methylene blue affect Tau fibrillization via cysteine oxidation A Crowe, MJ James, VMY Lee, AB Smith, JQ Trojanowski, C Ballatore, ... Journal of Biological Chemistry 288 (16), 11024-11037, 2013 | 169 | 2013 |
| The presence of substituents on the aryl moiety of the aryl phosphoramidate derivative of d4T enhances anti-HIV efficacy in cell culture: a structure− activity relationship AQ Siddiqui, C Ballatore, C McGuigan, E De Clercq, J Balzarini Journal of Medicinal Chemistry 42 (3), 393-399, 1999 | 166 | 1999 |
| High throughput screening for small molecule inhibitors of heparin-induced tau fibril formation A Crowe, C Ballatore, E Hyde, JQ Trojanowski, VMY Lee Biochemical and biophysical research communications 358 (1), 1-6, 2007 | 129 | 2007 |
| 1, 2, 4-Triazolo [1, 5-a] pyrimidines in drug design K Oukoloff, B Lucero, KR Francisco, KR Brunden, C Ballatore European journal of medicinal chemistry 165, 332-346, 2019 | 121 | 2019 |
| Microtubule-stabilizing agents as potential therapeutics for neurodegenerative disease KR Brunden, JQ Trojanowski, AB Smith III, VMY Lee, C Ballatore Bioorganic & medicinal chemistry 22 (18), 5040-5049, 2014 | 121 | 2014 |
| Identification of aminothienopyridazine inhibitors of tau assembly by quantitative high-throughput screening A Crowe, W Huang, C Ballatore, RL Johnson, AML Hogan, R Huang, ... Biochemistry 48 (32), 7732-7745, 2009 | 120 | 2009 |
| Tau-directed drug discovery for Alzheimer's disease and related tauopathies: a focus on tau assembly inhibitors KR Brunden, C Ballatore, A Crowe, AB Smith III, VMY Lee, ... Experimental neurology 223 (2), 304-310, 2010 | 115 | 2010 |
| Altered microtubule dynamics in neurodegenerative disease: Therapeutic potential of microtubule-stabilizing drugs KR Brunden, VMY Lee, AB Smith III, JQ Trojanowski, C Ballatore Neurobiology of disease 105, 328-335, 2017 | 114 | 2017 |
| Synthesis and evaluation of novel amidate prodrugs of PMEA and PMPA C Ballatore, C McGuigan, E De Clercq, J Balzarini Bioorganic & medicinal chemistry letters 11 (8), 1053-1056, 2001 | 109 | 2001 |
| Brain-penetrant, orally bioavailable microtubule-stabilizing small molecules are potential candidate therapeutics for Alzheimer’s disease and related tauopathies K Lou, Y Yao, AT Hoye, MJ James, AS Cornec, E Hyde, B Gay, VMY Lee, ... Journal of medicinal chemistry 57 (14), 6116-6127, 2014 | 107 | 2014 |
| Design and synthesis of lipophilic phosphoramidate d4T-MP prodrugs expressing high potency against HIV in cell culture: structural determinants for in vitro activity and QSAR AQ Siddiqui, C McGuigan, C Ballatore, F Zuccotto, IH Gilbert, E De Clercq, ... Journal of medicinal chemistry 42 (20), 4122-4128, 1999 | 104 | 1999 |
