| Therapeutic protein aggregation: mechanisms, design, and control CJ Roberts Trends in biotechnology 32 (7), 372-380, 2014 | 526 | 2014 |
| Non‐native protein aggregation kinetics CJ Roberts Biotechnology and bioengineering 98 (5), 927-938, 2007 | 413 | 2007 |
| Principles, approaches, and challenges for predicting protein aggregation rates and shelf life WF Weiss IV, TM Young, CJ Roberts Journal of pharmaceutical sciences 98 (4), 1246-1277, 2009 | 358 | 2009 |
| Protein aggregation and its impact on product quality CJ Roberts Current opinion in biotechnology 30, 211-217, 2014 | 342 | 2014 |
| Protein aggregation, particle formation, characterization & rheology S Amin, GV Barnett, JA Pathak, CJ Roberts, PS Sarangapani Current Opinion in Colloid & Interface Science 19 (5), 438-449, 2014 | 318 | 2014 |
| Protein aggregation–mechanisms, detection, and control W Wang, CJ Roberts International journal of pharmaceutics 550 (1-2), 251-268, 2018 | 288 | 2018 |
| Stabilization of pharmaceuticals to oxidative degradation KC Waterman, RC Adami, KM Alsante, J Hong, MS Landis, F Lombardo, ... Pharmaceutical development and technology 7 (1), 1-32, 2002 | 277 | 2002 |
| A Lumry− Eyring nucleated polymerization model of protein aggregation kinetics: 1. Aggregation with pre-equilibrated unfolding JM Andrews, CJ Roberts The Journal of Physical Chemistry B 111 (27), 7897-7913, 2007 | 266 | 2007 |
| Comparative effects of pH and ionic strength on protein–protein interactions, unfolding, and aggregation for IgG1 antibodies E Sahin, AO Grillo, MD Perkins, CJ Roberts Journal of pharmaceutical sciences 99 (12), 4830-4848, 2010 | 258 | 2010 |
| Aggregation of therapeutic proteins W Wang, CJ Roberts John Wiley & Sons, 2010 | 226 | 2010 |
| Kinetics of irreversible protein aggregation: analysis of extended Lumry− Eyring models and implications for predicting protein shelf life CJ Roberts The Journal of Physical Chemistry B 107 (5), 1194-1207, 2003 | 186 | 2003 |
| Liquid-liquid immiscibility in pure fluids: polyamorphism in simulations of a network-forming fluid CJ Roberts, AZ Panagiotopoulos, PG Debenedetti Physical review letters 77 (21), 4386, 1996 | 155 | 1996 |
| Non-Arrhenius protein aggregation W Wang, CJ Roberts The AAPS journal 15, 840-851, 2013 | 154 | 2013 |
| Polyamorphism and density anomalies in network‐forming fluids: Zeroth‐and first‐order approximations CJ Roberts, PG Debenedetti The Journal of chemical physics 105 (2), 658-672, 1996 | 153 | 1996 |
| Predicting solution aggregation rates for therapeutic proteins: approaches and challenges CJ Roberts, TK Das, E Sahin International journal of pharmaceutics 418 (2), 318-333, 2011 | 152 | 2011 |
| Structure and dynamics in concentrated, amorphous carbohydrate− water systems by molecular dynamics simulation CJ Roberts, PG Debenedetti The Journal of Physical Chemistry B 103 (34), 7308-7318, 1999 | 152 | 1999 |
| Nonnative aggregation of an IgG1 antibody in acidic conditions: part 1. Unfolding, colloidal interactions, and formation of high-molecular-weight aggregates RK Brummitt, DP Nesta, L Chang, SF Chase, TM Laue, CJ Roberts Journal of pharmaceutical sciences 100 (6), 2087-2103, 2011 | 145 | 2011 |
| Lumry− Eyring nucleated-polymerization model of protein aggregation kinetics. 2. Competing growth via condensation and chain polymerization Y Li, CJ Roberts The Journal of Physical Chemistry B 113 (19), 7020-7032, 2009 | 142 | 2009 |
| The equation of state of an energy landscape PG Debenedetti, FH Stillinger, TM Truskett, CJ Roberts The Journal of Physical Chemistry B 103 (35), 7390-7397, 1999 | 120 | 1999 |
| Size-exclusion chromatography with multi-angle light scattering for elucidating protein aggregation mechanisms E Sahin, CJ Roberts Therapeutic proteins: methods and protocols, 403-423, 2012 | 119 | 2012 |
