Distinct tau prion strains propagate in cells and mice and define different tauopathies DW Sanders, SK Kaufman, SL DeVos, AM Sharma, H Mirbaha, A Li, ... Neuron 82 (6), 1271-1288, 2014 | 1074 | 2014 |
Heparan sulfate proteoglycans mediate internalization and propagation of specific proteopathic seeds BB Holmes, SL DeVos, N Kfoury, M Li, R Jacks, K Yanamandra, ... Proceedings of the National Academy of Sciences 110 (33), E3138-E3147, 2013 | 939 | 2013 |
Tau reduction prevents neuronal loss and reverses pathological tau deposition and seeding in mice with tauopathy SL DeVos, RL Miller, KM Schoch, BB Holmes, CS Kebodeaux, ... Science translational medicine 9 (374), eaag0481, 2017 | 490 | 2017 |
Tau protein disrupts nucleocytoplasmic transport in Alzheimer’s disease B Eftekharzadeh, JG Daigle, LE Kapinos, A Coyne, J Schiantarelli, ... Neuron 99 (5), 925-940. e7, 2018 | 420 | 2018 |
Neuronal uptake and propagation of a rare phosphorylated high-molecular-weight tau derived from Alzheimer’s disease brain S Takeda, S Wegmann, H Cho, SL DeVos, C Commins, AD Roe, ... Nature communications 6 (1), 8490, 2015 | 389 | 2015 |
Antisense reduction of tau in adult mice protects against seizures SL DeVos, DK Goncharoff, G Chen, CS Kebodeaux, K Yamada, ... Journal of Neuroscience 33 (31), 12887-12897, 2013 | 364 | 2013 |
Synaptic tau seeding precedes tau pathology in human Alzheimer's disease brain SL DeVos, BT Corjuc, DH Oakley, CK Nobuhara, RN Bannon, A Chase, ... Frontiers in neuroscience 12, 267, 2018 | 302 | 2018 |
The role of microglia in processing and spreading of bioactive tau seeds in Alzheimer’s disease SC Hopp, Y Lin, D Oakley, AD Roe, SL DeVos, D Hanlon, BT Hyman Journal of neuroinflammation 15, 1-15, 2018 | 284 | 2018 |
Brain delivery of therapeutic proteins using an Fc fragment blood-brain barrier transport vehicle in mice and monkeys MS Kariolis, RC Wells, JA Getz, W Kwan, CS Mahon, R Tong, DJ Kim, ... Science translational medicine 12 (545), eaay1359, 2020 | 268 | 2020 |
Enhanced tau aggregation in the presence of amyloid β RE Bennett, SL DeVos, S Dujardin, B Corjuc, R Gor, J Gonzalez, AD Roe, ... The American journal of pathology 187 (7), 1601-1612, 2017 | 256 | 2017 |
Direct intraventricular delivery of drugs to the rodent central nervous system SL DeVos, TM Miller Journal of visualized experiments: JoVE, 50326, 2013 | 213 | 2013 |
Pathological correlations of [F‐18]‐AV‐1451 imaging in non‐alzheimer tauopathies M Marquié, MD Normandin, AC Meltzer, M Siao Tick Chong, NV Andrea, ... Annals of neurology 81 (1), 117-128, 2017 | 212 | 2017 |
Increased 4R-tau induces pathological changes in a human-tau mouse model KM Schoch, SL DeVos, RL Miller, SJ Chun, M Norrbom, DF Wozniak, ... Neuron 90 (5), 941-947, 2016 | 207 | 2016 |
Antisense oligonucleotides: treating neurodegeneration at the level of RNA SL DeVos, TM Miller Neurotherapeutics 10 (3), 486-497, 2013 | 192 | 2013 |
Rescue of a lysosomal storage disorder caused by Grn loss of function with a brain penetrant progranulin biologic T Logan, MJ Simon, A Rana, GM Cherf, A Srivastava, SS Davis, RLY Low, ... Cell 184 (18), 4651-4668. e25, 2021 | 155 | 2021 |
Removing endogenous tau does not prevent tau propagation yet reduces its neurotoxicity S Wegmann, EA Maury, MJ Kirk, L Saqran, A Roe, SL DeVos, S Nicholls, ... The EMBO journal 34 (24), 3028-3041, 2015 | 128 | 2015 |
Seed‐competent high‐molecular‐weight tau species accumulates in the cerebrospinal fluid of Alzheimer's disease mouse model and human patients S Takeda, C Commins, SL DeVos, CK Nobuhara, S Wegmann, AD Roe, ... Annals of neurology 80 (3), 355-367, 2016 | 121 | 2016 |
Tau antibody targeting pathological species blocks neuronal uptake and interneuron propagation of tau in vitro CK Nobuhara, SL DeVos, C Commins, S Wegmann, BD Moore, AD Roe, ... The American journal of pathology 187 (6), 1399-1412, 2017 | 114 | 2017 |
Tau reduction in the presence of amyloid-β prevents tau pathology and neuronal death in vivo SL DeVos, BT Corjuc, C Commins, S Dujardin, RN Bannon, D Corjuc, ... Brain 141 (7), 2194-2212, 2018 | 111 | 2018 |
In vivo rate-determining steps of tau seed accumulation in Alzheimer’s disease G Meisl, E Hidari, K Allinson, T Rittman, SL DeVos, JS Sanchez, CK Xu, ... Science advances 7 (44), eabh1448, 2021 | 107 | 2021 |