Crystal structure of the human cannabinoid receptor CB2 X Li, T Hua, K Vemuri, JH Ho, Y Wu, L Wu, P Popov, O Benchama, ... Cell 176 (3), 459-467. e13, 2019 | 405 | 2019 |
The therapeutic potential of second and third generation CB1R antagonists R Cinar, MR Iyer, G Kunos Pharmacology & therapeutics 208, 107477, 2020 | 126 | 2020 |
Antagonism of sigma-1 receptors blocks compulsive-like eating P Cottone, X Wang, JW Park, M Valenza, A Blasio, J Kwak, MR Iyer, ... Neuropsychopharmacology 37 (12), 2593-2604, 2012 | 100 | 2012 |
The σ-receptor antagonist BD-1063 decreases ethanol intake and reinforcement in animal models of excessive drinking V Sabino, P Cottone, Y Zhao, MR Iyer, L Steardo, KC Rice, B Conti, ... Neuropsychopharmacology 34 (6), 1482-1493, 2009 | 96 | 2009 |
Liposomes containing monophosphoryl lipid A: a potent adjuvant system for inducing antibodies to heroin hapten analogs GR Matyas, AV Mayorov, KC Rice, AE Jacobson, K Cheng, MR Iyer, F Li, ... Vaccine 31 (26), 2804-2810, 2013 | 94 | 2013 |
Hybrid inhibitor of peripheral cannabinoid-1 receptors and inducible nitric oxide synthase mitigates liver fibrosis R Cinar, MR Iyer, Z Liu, Z Cao, T Jourdan, K Erdelyi, G Godlewski, ... JCI insight 1 (11), 2016 | 77 | 2016 |
Cannabinoid CB1 receptor overactivity contributes to the pathogenesis of idiopathic pulmonary fibrosis R Cinar, BR Gochuico, MR Iyer, T Jourdan, T Yokoyama, JK Park, ... JCI insight 2 (8), 2017 | 71 | 2017 |
Activation of σ-receptors induces binge-like drinking in Sardinian alcohol-preferring rats V Sabino, P Cottone, A Blasio, MR Iyer, L Steardo, KC Rice, B Conti, ... Neuropsychopharmacology 36 (6), 1207-1218, 2011 | 67 | 2011 |
Facial recognition of heroin vaccine opiates: type 1 cross-reactivities of antibodies induced by hydrolytically stable haptenic surrogates of heroin, 6-acetylmorphine, and morphine GR Matyas, KC Rice, K Cheng, F Li, JFG Antoline, MR Iyer, AE Jacobson, ... Vaccine 32 (13), 1473-1479, 2014 | 62 | 2014 |
Promising Schiff bases in antiviral drug design and discovery S Kaushik, SK Paliwal, MR Iyer, VM Patil Medicinal Chemistry Research 32 (6), 1063-1076, 2023 | 56 | 2023 |
Dual inhibition of cannabinoid CB1 receptor and inducible NOS attenuates obesity‐induced chronic kidney disease S Udi, L Hinden, M Ahmad, A Drori, MR Iyer, R Cinar, ... British journal of pharmacology 177 (1), 110-127, 2020 | 56 | 2020 |
Characterization and optimization of heroin hapten-BSA conjugates: method development for the synthesis of reproducible hapten-based vaccines OB Torres, R Jalah, KC Rice, F Li, JFG Antoline, MR Iyer, AE Jacobson, ... Analytical and Bioanalytical Chemistry 406, 5927-5937, 2014 | 56 | 2014 |
Allenyl azide cycloaddition chemistry. synthesis of pyrrolidine-containing bicycles and tricycles via the possible intermediacy of azatrimethylenemethane species KS Feldman, MR Iyer Journal of the American Chemical Society 127 (13), 4590-4591, 2005 | 51 | 2005 |
Allenyl azide cycloaddition chemistry. Synthesis of annelated indoles from 2-(allenyl) phenyl azide substrates KS Feldman, MR Iyer, DK Hester Organic letters 8 (14), 3113-3116, 2006 | 50 | 2006 |
Targeting peripheral CB1 receptors reduces ethanol intake via a gut-brain axis G Godlewski, R Cinar, NJ Coffey, J Liu, T Jourdan, B Mukhopadhyay, ... Cell metabolism 29 (6), 1320-1333. e8, 2019 | 46 | 2019 |
Cocaine reward is reduced by decreased expression of receptor-type protein tyrosine phosphatase D (PTPRD) and by a novel PTPRD antagonist GR Uhl, MJ Martinez, P Paik, A Sulima, GH Bi, MR Iyer, E Gardner, ... Proceedings of the National Academy of Sciences 115 (45), 11597-11602, 2018 | 42 | 2018 |
Functional Selectivity of a Biased Cannabinoid-1 Receptor (CB1R) Antagonist Z Liu, MR Iyer, G Godlewski, T Jourdan, J Liu, NJ Coffey, CN Zawatsky, ... ACS Pharmacology & Translational Science 4 (3), 1175-1187, 2021 | 41 | 2021 |
Design, Synthesis, and Biological Evaluation of Novel, Non-Brain-Penetrant, Hybrid Cannabinoid CB1R Inverse Agonist/Inducible Nitric Oxide Synthase (iNOS … MR Iyer, R Cinar, A Katz, M Gao, K Erdelyi, T Jourdan, NJ Coffey, ... Journal of Medicinal Chemistry 60 (3), 1126-1141, 2017 | 40 | 2017 |
Sigma-1 receptor mediates acquisition of alcohol drinking and seeking behavior in alcohol-preferring rats A Blasio, M Valenza, MR Iyer, KC Rice, L Steardo, T Hayashi, P Cottone, ... Behavioural brain research 287, 315-322, 2015 | 40 | 2015 |
Synthesis and immunological effects of heroin vaccines F Li, K Cheng, JFG Antoline, MR Iyer, GR Matyas, OB Torres, R Jalah, ... Organic & biomolecular chemistry 12 (37), 7211-7232, 2014 | 38 | 2014 |