| Transcriptome-wide identification of RNA-binding protein and microRNA target sites by PAR-CLIP M Hafner, M Landthaler, L Burger, M Khorshid, J Hausser, P Berninger, ... Cell 141 (1), 129-141, 2010 | 3342 | 2010 |
| Cyclic [G (2′, 5′) pA (3′, 5′) p] is the metazoan second messenger produced by DNA-activated cyclic GMP-AMP synthase P Gao, M Ascano, Y Wu, W Barchet, BL Gaffney, T Zillinger, AA Serganov, ... Cell 153 (5), 1094-1107, 2013 | 1079 | 2013 |
| FMRP targets distinct mRNA sequence elements to regulate protein expression M Ascano, N Mukherjee, P Bandaru, JB Miller, JD Nusbaum, DL Corcoran, ... Nature 492 (7429), 382-386, 2012 | 782 | 2012 |
| Integrative regulatory mapping indicates that the RNA-binding protein HuR couples pre-mRNA processing and mRNA stability N Mukherjee, DL Corcoran, JD Nusbaum, DW Reid, S Georgiev, ... Molecular cell 43 (3), 327-339, 2011 | 721 | 2011 |
| Structure-function analysis of STING activation by c [G (2′, 5′) pA (3′, 5′) p] and targeting by antiviral DMXAA P Gao, M Ascano, T Zillinger, W Wang, P Dai, AA Serganov, BL Gaffney, ... Cell 154 (4), 748-762, 2013 | 596 | 2013 |
| Endosomolytic polymersomes increase the activity of cyclic dinucleotide STING agonists to enhance cancer immunotherapy D Shae, KW Becker, P Christov, DS Yun, AKR Lytton-Jean, S Sevimli, ... Nature nanotechnology 14 (3), 269-278, 2019 | 577 | 2019 |
| PAR-CliP-a method to identify transcriptome-wide the binding sites of RNA binding proteins M Hafner, M Landthaler, L Burger, M Khorshid, J Hausser, P Berninger, ... Journal of visualized experiments: JoVE, 2034, 2010 | 367 | 2010 |
| Identification of RNA–protein interaction networks using PAR‐CLIP M Ascano, M Hafner, P Cekan, S Gerstberger, T Tuschl Wiley Interdisciplinary Reviews: RNA 3 (2), 159-177, 2012 | 310 | 2012 |
| Small molecule inhibition of cGAS reduces interferon expression in primary macrophages from autoimmune mice J Vincent, C Adura, P Gao, A Luz, L Lama, Y Asano, R Okamoto, ... Nature communications 8 (1), 750, 2017 | 291 | 2017 |
| Evolutionary conservation and expression of human RNA-binding proteins and their role in human genetic disease S Gerstberger, M Hafner, M Ascano, T Tuschl Systems biology of RNA binding proteins, 1-55, 2014 | 172 | 2014 |
| Regulation of Hedgehog signaling: a complex story SK Ogden, M Ascano Jr, MA Stegman, DJ Robbins Biochemical pharmacology 67 (5), 805-814, 2004 | 152 | 2004 |
| Identification of a functional interaction between the transmembrane protein Smoothened and the kinesin-related protein Costal2 SK Ogden, M Ascano, MA Stegman, LM Suber, JE Hooper, DJ Robbins Current biology 13 (22), 1998-2003, 2003 | 141 | 2003 |
| PAR-CLIP (Photoactivatable Ribonucleoside-Enhanced Crosslinking and Immunoprecipitation): a step-by-step protocol to the transcriptome-wide identification of binding sites of … J Spitzer, M Hafner, M Landthaler, M Ascano, T Farazi, G Wardle, ... Methods in enzymology 539, 113-161, 2014 | 119 | 2014 |
| Eukaryote-specific insertion elements control human ARGONAUTE slicer activity K Nakanishi, M Ascano, T Gogakos, S Ishibe-Murakami, AA Serganov, ... Cell reports 3 (6), 1893-1900, 2013 | 116 | 2013 |
| Binding-pocket and lid-region substitutions render human STING sensitive to the species-specific drug DMXAA P Gao, T Zillinger, W Wang, M Ascano, P Dai, G Hartmann, T Tuschl, ... Cell reports 8 (6), 1668-1676, 2014 | 109 | 2014 |
| Discovery of widespread host protein interactions with the pre-replicated genome of CHIKV using VIR-CLASP B Kim, S Arcos, K Rothamel, J Jian, KL Rose, WH McDonald, Y Bian, ... Molecular Cell 78 (4), 624-640. e7, 2020 | 93 | 2020 |
| Multimeric assembly and biochemical characterization of the Trax–translin endonuclease complex Y Tian, DK Simanshu, M Ascano, R Diaz-Avalos, AY Park, SA Juranek, ... Nature structural & molecular biology 18 (6), 658-664, 2011 | 76 | 2011 |
| Multi-disciplinary methods to define RNA–protein interactions and regulatory networks M Ascano, S Gerstberger, T Tuschl Current opinion in genetics & development 23 (1), 20-28, 2013 | 68 | 2013 |
| Costal2 functions as a kinesin-like protein in the hedgehog signal transduction pathway SF Farzan, M Ascano, SK Ogden, M Sanial, A Brigui, A Plessis, ... Current Biology 18 (16), 1215-1220, 2008 | 68 | 2008 |
| Augmented noncanonical BMP type II receptor signaling mediates the synaptic abnormality of fragile X syndrome R Kashima, S Roy, M Ascano, V Martinez-Cerdeno, J Ariza-Torres, S Kim, ... Science signaling 9 (431), ra58-ra58, 2016 | 67 | 2016 |
Thomas TuschlThe Rockefeller UniversityVerified email at rockefeller.edu