| Fatal systemic inflammatory response syndrome in a ornithine transcarbamylase deficient patient following adenoviral gene transfer SE Raper, N Chirmule, FS Lee, NA Wivel, A Bagg, G Gao, JM Wilson, ... Molecular genetics and metabolism 80 (1-2), 148-158, 2003 | 1939 | 2003 |
| Immune responses to adenovirus and adeno-associated virus in humans N Chirmule, KJ Propert, SA Magosin, Y Qian, R Qian, JM Wilson Gene therapy 6 (9), 1574-1583, 1999 | 916 | 1999 |
| Gene therapy vectors based on adeno-associated virus type 1 W Xiao, N Chirmule, SC Berta, B McCullough, G Gao, JM Wilson Journal of virology 73 (5), 3994-4003, 1999 | 769 | 1999 |
| Acute cytokine response to systemic adenoviral vectors in mice is mediated by dendritic cells and macrophages Y Zhang, N Chirmule, G Gao, R Qian, M Croyle, B Joshi, J Tazelaar, ... Molecular Therapy 3 (5), 697-707, 2001 | 485 | 2001 |
| A pilot study of in vivo liver-directed gene transfer with an adenoviral vector in partial ornithine transcarbamylase deficiency SE Raper, M Yudkoff, N Chirmule, GP Gao, F Nunes, ZJ Haskal, EE Furth, ... Human gene therapy 13 (1), 163-175, 2002 | 470 | 2002 |
| Immunity to adenovirus and adeno-associated viral vectors: implications for gene therapy K Jooss, N Chirmule Gene therapy 10 (11), 955-963, 2003 | 376 | 2003 |
| Simultaneous quantitation of antibodies to neutralizing epitopes on virus-like particles for human papillomavirus types 6, 11, 16, and 18 by a multiplexed luminex assay D Opalka, CE Lachman, SA MacMullen, KU Jansen, JF Smith, N Chirmule, ... Clinical and Vaccine Immunology 10 (1), 108-115, 2003 | 355 | 2003 |
| Immunogenicity to therapeutic proteins: impact on PK/PD and efficacy N Chirmule, V Jawa, B Meibohm The AAPS journal 14, 296-302, 2012 | 349 | 2012 |
| Highly aggregated antibody therapeutics can enhance the in vitro innate and late-stage T-cell immune responses MK Joubert, M Hokom, C Eakin, L Zhou, M Deshpande, MP Baker, ... Journal of Biological Chemistry 287 (30), 25266-25279, 2012 | 308 | 2012 |
| “Stealth” adenoviruses blunt cell-mediated and humoral immune responses against the virus and allow for significant gene expression upon readministration in the lung MA Croyle, N Chirmule, Y Zhang, JM Wilson Journal of virology 75 (10), 4792-4801, 2001 | 307 | 2001 |
| Stable transgene expression in rod photoreceptors after recombinant adeno-associated virus-mediated gene transfer to monkey retina J Bennett, AM Maguire, AV Cideciyan, M Schnell, E Glover, V Anand, ... Proceedings of the National Academy of Sciences 96 (17), 9920-9925, 1999 | 307 | 1999 |
| Optimization and validation of a multiplexed luminex assay to quantify antibodies to neutralizing epitopes on human papillomaviruses 6, 11, 16, and 18 D Dias, J Van Doren, S Schlottmann, S Kelly, D Puchalski, W Ruiz, ... Clinical and Vaccine Immunology 12 (8), 959-969, 2005 | 289 | 2005 |
| Memory T cells and vaccines MT Esser, RD Marchese, LS Kierstead, LG Tussey, F Wang, N Chirmule, ... Vaccine 21 (5-6), 419-430, 2003 | 284 | 2003 |
| Hybrid vectors based on adeno-associated virus serotypes 2 and 5 for muscle-directed gene transfer M Hildinger, A Auricchio, G Gao, L Wang, N Chirmule, JM Wilson Journal of virology 75 (13), 6199-6203, 2001 | 271 | 2001 |
| Accelerated apoptosis in peripheral blood mononuclear cells (PBMCs) from human immunodeficiency virus type-1 infected patients and in CD4 cross-linked PBMCs from normal individuals N Oyaizu, TW McCloskey, M Coronesi, N Chirmule, VS Kalyanaraman, ... | 261 | 1993 |
| Immune hyperactivation of HIV-1-infected T cells mediated by Tat and the CD28 pathway M Ott, S Emiliani, C Van Lint, G Herbein, J Lovett, N Chirmule, ... Science 275 (5305), 1481-1485, 1997 | 256 | 1997 |
| Humoral immunity to adeno-associated virus type 2 vectors following administration to murine and nonhuman primate muscle N Chirmule, W Xiao, A Truneh, MA Schnell, JV Hughes, P Zoltick, ... Journal of virology 74 (5), 2420-2425, 2000 | 248 | 2000 |
| Immunogenicity of biotherapeutics: causes and association with posttranslational modifications A Kuriakose, N Chirmule, P Nair Journal of immunology research 2016 (1), 1298473, 2016 | 240 | 2016 |
| Purification of recombinant adeno-associated virus vectors by column chromatography and its performance in vivo G Gao, G Qu, MS Burnham, J Huang, N Chirmule, B Joshi, QC Yu, ... Human gene therapy 11 (15), 2079-2091, 2000 | 232 | 2000 |
| PEGylation of E1-deleted adenovirus vectors allows significant gene expression on readministration to liver MA Croyle, N Chirmule, Y Zhang, JM Wilson Human gene therapy 13 (15), 1887-1900, 2002 | 204 | 2002 |