An antifungal agent inhibits an aminoacyl-tRNA synthetase by trapping tRNA in the editing site FL Rock, W Mao, A Yaremchuk, M Tukalo, T Crépin, H Zhou, YK Zhang, ... science 316 (5832), 1759-1761, 2007 | 709 | 2007 |
Discovery of a new boron-containing antifungal agent, 5-fluoro-1, 3-dihydro-1-hydroxy-2, 1-benzoxaborole (AN2690), for the potential treatment of onychomycosis SJ Baker, YK Zhang, T Akama, A Lau, H Zhou, V Hernandez, W Mao, ... Journal of medicinal chemistry 49 (15), 4447-4450, 2006 | 378 | 2006 |
Pattern recognition of proteins based on an array of functionalized porphyrins H Zhou, L Baldini, J Hong, AJ Wilson, AD Hamilton Journal of the American Chemical Society 128 (7), 2421-2425, 2006 | 277 | 2006 |
Discovery and structure–activity study of a novel benzoxaborole anti-inflammatory agent (AN2728) for the potential topical treatment of psoriasis and atopic dermatitis T Akama, SJ Baker, YK Zhang, V Hernandez, H Zhou, V Sanders, ... Bioorganic & medicinal chemistry letters 19 (8), 2129-2132, 2009 | 271 | 2009 |
Adenanthin targets peroxiredoxin I and II to induce differentiation of leukemic cells CX Liu, QQ Yin, HC Zhou, YL Wu, JX Pu, L Xia, W Liu, X Huang, T Jiang, ... Nature chemical biology 8 (5), 486-493, 2012 | 235 | 2012 |
Small molecule targeting Cdc42–intersectin interaction disrupts Golgi organization and suppresses cell motility A Friesland, Y Zhao, YH Chen, L Wang, H Zhou, Q Lu Proceedings of the National Academy of Sciences 110 (4), 1261-1266, 2013 | 192 | 2013 |
Synthesis of biologically active boron-containing compounds F Yang, M Zhu, J Zhang, H Zhou MedChemComm 9 (2), 201-211, 2018 | 129 | 2018 |
Azobenzene-based small molecular photoswitches for protein modulation M Zhu, H Zhou Organic & biomolecular chemistry 16 (44), 8434-8445, 2018 | 121 | 2018 |
Boron-containing small molecules SJ Baker, T Akama, VS Hernandez, KM Hold, KR Maples, JJ Plattner, ... US Patent 7,767,657, 2010 | 114* | 2010 |
Boron-containing small molecules as anti-inflammatory agents SJ Baker, V Sanders, T Akama, C Bellinger-Kawahara, Y Freund, ... US Patent 8,168,614, 2012 | 112 | 2012 |
Design, Synthesis, and Structure−Activity Relationship of Trypanosoma brucei Leucyl-tRNA Synthetase Inhibitors as Antitrypanosomal Agents D Ding, Q Meng, G Gao, Y Zhao, Q Wang, B Nare, R Jacobs, F Rock, ... Journal of medicinal chemistry 54 (5), 1276-1287, 2011 | 108 | 2011 |
Signaling through Rho GTPase pathway as viable drug target Q Lu, FM Longo, H Zhou, SM Massa, YH Chen Current medicinal chemistry 16 (11), 1355-1365, 2009 | 107 | 2009 |
Discovery of novel benzoxaborole-based potent antitrypanosomal agents D Ding, Y Zhao, Q Meng, D Xie, B Nare, D Chen, CJ Bacchi, N Yarlett, ... ACS medicinal chemistry letters 1 (4), 165-169, 2010 | 106 | 2010 |
Characterization of the polyoxin biosynthetic gene cluster from Streptomyces cacaoi and engineered production of polyoxin H W Chen, T Huang, X He, Q Meng, D You, L Bai, J Li, M Wu, R Li, Z Xie, ... Journal of Biological Chemistry 284 (16), 10627-10638, 2009 | 103 | 2009 |
Chalcone–benzoxaborole hybrid molecules as potent antitrypanosomal agents Z Qiao, Q Wang, F Zhang, Z Wang, T Bowling, B Nare, RT Jacobs, ... Journal of Medicinal Chemistry 55 (7), 3553-3557, 2012 | 102 | 2012 |
Functional characterization of three mouse formyl peptide receptors HQ He, D Liao, ZG Wang, ZL Wang, HC Zhou, MW Wang, DY Richard Molecular pharmacology 83 (2), 389-398, 2013 | 95 | 2013 |
Advances in the development ubiquitin-specific peptidase (USP) inhibitors S Chen, Y Liu, H Zhou International journal of molecular sciences 22 (9), 4546, 2021 | 93 | 2021 |
Discovery of a potent benzoxaborole-based anti-pneumococcal agent targeting leucyl-tRNA synthetase QH Hu, RJ Liu, ZP Fang, J Zhang, YY Ding, M Tan, M Wang, W Pan, ... Scientific reports 3 (1), 2475, 2013 | 93 | 2013 |
Structure–activity studies on a library of potent calix [4] arene-based PDGF antagonists that inhibit PDGF-stimulated PDGFR tyrosine phosphorylation H Zhou, D Wang, L Baldini, E Ennis, R Jain, A Carie, SM Sebti, ... Organic & Biomolecular Chemistry 4 (12), 2376-2386, 2006 | 78 | 2006 |
Benzoxaborole antimalarial agents. Part 2: Discovery of fluoro-substituted 7-(2-carboxyethyl)-1, 3-dihydro-1-hydroxy-2, 1-benzoxaboroles YK Zhang, JJ Plattner, YR Freund, EE Easom, Y Zhou, L Ye, H Zhou, ... Bioorganic & medicinal chemistry letters 22 (3), 1299-1307, 2012 | 60 | 2012 |