Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir W Yin, C Mao, X Luan, DD Shen, Q Shen, H Su, X Wang, F Zhou, W Zhao, ... Science 368 (6498), 1499-1504, 2020 | 1280 | 2020 |
Structural insights into the lipid and ligand regulation of serotonin receptors P Xu, S Huang, H Zhang, C Mao, XE Zhou, X Cheng, IA Simon, DD Shen, ... Nature 592 (7854), 469-473, 2021 | 210 | 2021 |
Structural insights into the human D1 and D2 dopamine receptor signaling complexes Y Zhuang, P Xu, C Mao, L Wang, B Krumm, XE Zhou, S Huang, H Liu, ... Cell 184 (4), 931-942. e18, 2021 | 206 | 2021 |
Structures of the glucocorticoid-bound adhesion receptor GPR97–Go complex YQ Ping, C Mao, P Xiao, RJ Zhao, Y Jiang, Z Yang, WT An, DD Shen, ... Nature 589 (7843), 620-626, 2021 | 138 | 2021 |
Structural basis of GPBAR activation and bile acid recognition F Yang, C Mao, L Guo, J Lin, Q Ming, P Xiao, X Wu, Q Shen, S Guo, ... Nature 587 (7834), 499-504, 2020 | 132 | 2020 |
Cryo-EM structures of inactive and active GABAB receptor C Mao, C Shen, C Li, DD Shen, C Xu, S Zhang, R Zhou, Q Shen, LN Chen, ... Cell research 30 (7), 564-573, 2020 | 106 | 2020 |
GPCRs steer Gi and Gs selectivity via TM5-TM6 switches as revealed by structures of serotonin receptors S Huang, P Xu, DD Shen, IA Simon, C Mao, Y Tan, H Zhang, K Harpsøe, ... Molecular cell 82 (14), 2681-2695. e6, 2022 | 86 | 2022 |
Structures of full-length glycoprotein hormone receptor signalling complexes J Duan, P Xu, X Cheng, C Mao, T Croll, X He, J Shi, X Luan, W Yin, E You, ... Nature 598 (7882), 688-692, 2021 | 83 | 2021 |
Structural basis of GABAB receptor–Gi protein coupling C Shen, C Mao, C Xu, N Jin, H Zhang, DD Shen, Q Shen, X Wang, T Hou, ... Nature 594 (7864), 594-598, 2021 | 80 | 2021 |
Molecular basis for hormone recognition and activation of corticotropin-releasing factor receptors S Ma, Q Shen, LH Zhao, C Mao, XE Zhou, DD Shen, PW de Waal, P Bi, ... Molecular cell 77 (3), 669-680. e4, 2020 | 77 | 2020 |
Structures of the human dopamine D3 receptor-Gi complexes P Xu, S Huang, C Mao, BE Krumm, XE Zhou, Y Tan, XP Huang, Y Liu, ... Molecular Cell 81 (6), 1147-1159. e4, 2021 | 73 | 2021 |
Identification and mechanism of G protein-biased ligands for chemokine receptor CCR1 Z Shao, Q Shen, B Yao, C Mao, LN Chen, H Zhang, DD Shen, C Zhang, ... Nature chemical biology 18 (3), 264-271, 2022 | 70 | 2022 |
Unsaturated bond recognition leads to biased signal in a fatty acid receptor C Mao, P Xiao, XN Tao, J Qin, QT He, C Zhang, SC Guo, YQ Du, LN Chen, ... Science 380 (6640), eadd6220, 2023 | 68 | 2023 |
Structural basis for activation of the growth hormone-releasing hormone receptor F Zhou, H Zhang, Z Cong, LH Zhao, Q Zhou, C Mao, X Cheng, DD Shen, ... Nature communications 11 (1), 5205, 2020 | 68 | 2020 |
Molecular insights into ligand recognition and activation of chemokine receptors CCR2 and CCR3 Z Shao, Y Tan, Q Shen, L Hou, B Yao, J Qin, P Xu, C Mao, LN Chen, ... Cell Discovery 8 (1), 44, 2022 | 56 | 2022 |
Structural insights into ligand recognition and activation of the melanocortin-4 receptor H Zhang, LN Chen, D Yang, C Mao, Q Shen, W Feng, DD Shen, A Dai, ... Cell Research 31 (11), 1163-1175, 2021 | 42 | 2021 |
Ligand recognition, unconventional activation, and G protein coupling of the prostaglandin E2 receptor EP2 subtype C Qu, C Mao, P Xiao, Q Shen, YN Zhong, F Yang, DD Shen, X Tao, ... Science Advances 7 (14), eabf1268, 2021 | 40 | 2021 |
Molecular mechanism of agonism and inverse agonism in ghrelin receptor J Qin, Y Cai, Z Xu, Q Ming, SY Ji, C Wu, H Zhang, C Mao, DD Shen, ... Nature Communications 13 (1), 300, 2022 | 39 | 2022 |
Constitutive signal bias mediated by the human GHRHR splice variant 1 Z Cong, F Zhou, C Zhang, X Zou, H Zhang, Y Wang, Q Zhou, X Cai, Q Liu, ... Proceedings of the National Academy of Sciences 118 (40), e2106606118, 2021 | 26 | 2021 |
Mechanism of hormone and allosteric agonist mediated activation of follicle stimulating hormone receptor J Duan, P Xu, H Zhang, X Luan, J Yang, X He, C Mao, DD Shen, Y Ji, ... Nature Communications 14 (1), 519, 2023 | 23 | 2023 |