The Skp2-SCF E3 ligase regulates Akt ubiquitination, glycolysis, herceptin sensitivity, and tumorigenesis CH Chan, CF Li, WL Yang, Y Gao, SW Lee, Z Feng, HY Huang, KKC Tsai, ... Cell 149 (5), 1098-1111, 2012 | 443 | 2012 |
Pharmacological inactivation of Skp2 SCF ubiquitin ligase restricts cancer stem cell traits and cancer progression CH Chan, JK Morrow, CF Li, Y Gao, G Jin, A Moten, LJ Stagg, JE Ladbury, ... Cell 154 (3), 556-568, 2013 | 415 | 2013 |
Deciphering the transcriptional complex critical for RhoA gene expression and cancer metastasis CH Chan, SW Lee, CF Li, J Wang, WL Yang, CY Wu, J Wu, KI Nakayama, ... Nature cell biology 12 (5), 457-467, 2010 | 242 | 2010 |
The critical role of AMPK in driving Akt activation under stress, tumorigenesis and drug resistance F Han, CF Li, Z Cai, X Zhang, G Jin, WN Zhang, C Xu, CY Wang, J Morrow, ... Nature communications 9 (1), 4728, 2018 | 168 | 2018 |
Phosphorylation of PDHA by AMPK drives TCA cycle to promote cancer metastasis Z Cai, CF Li, F Han, C Liu, A Zhang, CC Hsu, D Peng, X Zhang, G Jin, ... Molecular cell 80 (2), 263-278. e7, 2020 | 163 | 2020 |
NAB2–STAT6 fusion types account for clinicopathological variations in solitary fibrous tumors HC Tai, IC Chuang, TC Chen, CF Li, SC Huang, YC Kao, PC Lin, JW Tsai, ... Modern Pathology 28 (10), 1324-1335, 2015 | 162 | 2015 |
Cancer/stroma interplay via cyclooxygenase-2 and indoleamine 2, 3-dioxygenase promotes breast cancer progression JY Chen, CF Li, CC Kuo, KK Tsai, MF Hou, WC Hung Breast Cancer Research 16, 1-14, 2014 | 158 | 2014 |
ASS1 as a Novel Tumor Suppressor Gene in Myxofibrosarcomas: Aberrant Loss via Epigenetic DNA Methylation Confers Aggressive Phenotypes, Negative … HY Huang, WR Wu, YH Wang, JW Wang, FM Fang, JW Tsai, SH Li, ... Clinical cancer research 19 (11), 2861-2872, 2013 | 153 | 2013 |
Promoter methylation of argininosuccinate synthetase-1 sensitises lymphomas to arginine deiminase treatment, autophagy and caspase-dependent apoptosis B Delage, P Luong, L Maharaj, C O’riain, N Syed, T Crook, ... Cell death & disease 3 (7), e342-e342, 2012 | 152 | 2012 |
A modification of NIH consensus criteria to better distinguish the highly lethal subset of primary localized gastrointestinal stromal tumors: a subdivision of the original high … HY Huang, CF Li, WW Huang, TH Hu, CN Lin, YH Uen, CY Hsiung, D Lu Surgery 141 (6), 748-756, 2007 | 145 | 2007 |
Prognostic and therapeutic impact of argininosuccinate synthetase 1 control in bladder cancer as monitored longitudinally by PET imaging MD Allen, P Luong, C Hudson, J Leyton, B Delage, E Ghazaly, R Cutts, ... Cancer research 74 (3), 896-907, 2014 | 144 | 2014 |
Skp2-dependent ubiquitination and activation of LKB1 is essential for cancer cell survival under energy stress SW Lee, CF Li, G Jin, Z Cai, F Han, CH Chan, WL Yang, BK Li, ... Molecular cell 57 (6), 1022-1033, 2015 | 135 | 2015 |
Skp2–MacroH2A1–CDK8 axis orchestrates G2/M transition and tumorigenesis D Xu, CF Li, X Zhang, Z Gong, CH Chan, SW Lee, G Jin, AH Rezaeian, ... Nature communications 6 (1), 6641, 2015 | 119 | 2015 |
α2-Adrenoceptor agonist dexmedetomidine protects septic acute kidney injury through increasing BMP-7 and inhibiting HDAC2 and HDAC5 CH Hsing, CF Lin, E So, DP Sun, TC Chen, CF Li, CH Yeh American Journal of Physiology-Renal Physiology 303 (10), F1443-F1453, 2012 | 117 | 2012 |
ALK oncoproteins in atypical inflammatory myofibroblastic tumours: novel RRBP1‐ALK fusions in epithelioid inflammatory myofibroblastic sarcoma JC Lee, CF Li, HY Huang, MJ Zhu, A Mariño‐Enríquez, CT Lee, WB Ou, ... The Journal of pathology 241 (3), 316-323, 2017 | 113 | 2017 |
Non-proteolytic ubiquitination of Hexokinase 2 by HectH9 controls tumor metabolism and cancer stem cell expansion HJ Lee, CF Li, D Ruan, J He, ED Montal, S Lorenz, GD Girnun, CH Chan Nature communications 10 (1), 2625, 2019 | 111 | 2019 |
Overexpression of nuclear protein kinase CK2 α catalytic subunit (CK2α) as a poor prognosticator in human colorectal cancer KY Lin, C Tai, JC Hsu, CF Li, CL Fang, HC Lai, YC Hseu, YF Lin, YH Uen PloS one 6 (2), e17193, 2011 | 110 | 2011 |
A hypoxia-responsive TRAF6–ATM–H2AX signalling axis promotes HIF1α activation, tumorigenesis and metastasis AH Rezaeian, CF Li, CY Wu, X Zhang, J Delacerda, MJ You, F Han, Z Cai, ... Nature cell biology 19 (1), 38-51, 2017 | 109 | 2017 |
KDM8/JMJD5 as a dual coactivator of AR and PKM2 integrates AR/EZH2 network and tumor metabolism in CRPC HJ Wang, M Pochampalli, LY Wang, JX Zou, PS Li, SC Hsu, BJ Wang, ... Oncogene 38 (1), 17-32, 2019 | 93 | 2019 |
Decreased succinate dehydrogenase B in human hepatocellular carcinoma accelerates tumor malignancy by inducing the Warburg effect PL Tseng, WH Wu, TH Hu, CW Chen, HC Cheng, CF Li, WH Tsai, HJ Tsai, ... Scientific reports 8 (1), 3081, 2018 | 93 | 2018 |