Mutational heterogeneity in cancer and the search for new cancer-associated genes MS Lawrence, P Stojanov, P Polak, GV Kryukov, K Cibulskis, ... Nature 499 (7457), 214-218, 2013 | 6100 | 2013 |
Whole-genome sequencing in autism identifies hot spots for de novo germline mutation JJ Michaelson, Y Shi, M Gujral, H Zheng, D Malhotra, X Jin, M Jian, G Liu, ... Cell 151 (7), 1431-1442, 2012 | 687 | 2012 |
Cell-of-origin chromatin organization shapes the mutational landscape of cancer P Polak, R Karlić, A Koren, R Thurman, R Sandstrom, MS Lawrence, ... Nature 518 (7539), 360-364, 2015 | 611 | 2015 |
Mutational strand asymmetries in cancer genomes reveal mechanisms of DNA damage and repair NJ Haradhvala, P Polak, P Stojanov, KR Covington, E Shinbrot, JM Hess, ... Cell 164 (3), 538-549, 2016 | 454 | 2016 |
Genome-wide patterns and properties of de novo mutations in humans LC Francioli, PP Polak, A Koren, A Menelaou, S Chun, I Renkens, ... Nature genetics 47 (7), 822-826, 2015 | 428 | 2015 |
Differential relationship of DNA replication timing to different forms of human mutation and variation A Koren, P Polak, J Nemesh, JJ Michaelson, J Sebat, SR Sunyaev, ... The American Journal of Human Genetics 91 (6), 1033-1040, 2012 | 278 | 2012 |
T cell help controls the speed of the cell cycle in germinal center B cells AD Gitlin, CT Mayer, TY Oliveira, Z Shulman, MJK Jones, A Koren, ... Science 349 (6248), 643-646, 2015 | 270 | 2015 |
Genetic variation in human DNA replication timing A Koren, RE Handsaker, N Kamitaki, R Karlić, S Ghosh, P Polak, K Eggan, ... Cell 159 (5), 1015-1026, 2014 | 172 | 2014 |
ELG1, a yeast gene required for genome stability, forms a complex related to replication factor C S Ben-Aroya, A Koren, B Liefshitz, R Steinlauf, M Kupiec Proceedings of the National Academy of Sciences 100 (17), 9906-9911, 2003 | 146 | 2003 |
Analysis of somatic microsatellite indels identifies driver events in human tumors YE Maruvka, KW Mouw, R Karlic, P Parasuraman, A Kamburov, P Polak, ... Nature biotechnology 35 (10), 951-959, 2017 | 140 | 2017 |
Epigenetically-inherited centromere and neocentromere DNA replicates earliest in S-phase A Koren, HJ Tsai, I Tirosh, LS Burrack, N Barkai, J Berman PLoS genetics 6 (8), e1001068, 2010 | 98 | 2010 |
MRC1-dependent scaling of the budding yeast DNA replication timing program A Koren, I Soifer, N Barkai Genome research 20 (6), 781-790, 2010 | 87 | 2010 |
Random replication of the inactive X chromosome A Koren, SA McCarroll Genome research 24 (1), 64-69, 2014 | 75 | 2014 |
DNA replication timing during development anticipates transcriptional programs and parallels enhancer activation JC Siefert, C Georgescu, JD Wren, A Koren, CL Sansam Genome research 27 (8), 1406-1416, 2017 | 74 | 2017 |
Replication stress impairs chromosome segregation and preimplantation development in human embryos KL Palmerola, S Amrane, A De Los Angeles, S Xu, N Wang, J de Pinho, ... Cell 185 (16), 2988-3007. e20, 2022 | 70 | 2022 |
Genomic signature of Fanconi anaemia DNA repair pathway deficiency in cancer ALH Webster, MA Sanders, K Patel, R Dietrich, RJ Noonan, FP Lach, ... Nature 612 (7940), 495-502, 2022 | 51 | 2022 |
Genomic methods for measuring DNA replication dynamics ML Hulke, DJ Massey, A Koren Chromosome Research 28 (1), 49-67, 2020 | 51 | 2020 |
The genetic architecture of DNA replication timing in human pluripotent stem cells Q Ding, MM Edwards, N Wang, X Zhu, AN Bracci, ML Hulke, Y Hu, Y Tong, ... Nature communications 12 (1), 6746, 2021 | 44 | 2021 |
Germline DNA replication timing shapes mammalian genome composition Y Yehuda, B Blumenfeld, N Mayorek, K Makedonski, O Vardi, ... Nucleic acids research 46 (16), 8299-8310, 2018 | 38 | 2018 |
Control of meiotic recombination initiation: a role for the environment? A Koren, S Ben-Aroya, M Kupiec Current genetics 42, 129-139, 2002 | 38 | 2002 |