| Sphingosine-1-phosphate links persistent STAT3 activation, chronic intestinal inflammation, and development of colitis-associated cancer J Liang, M Nagahashi, EY Kim, KB Harikumar, A Yamada, WC Huang, ... Cancer cell 23 (1), 107-120, 2013 | 616 | 2013 |
| Active, phosphorylated fingolimod inhibits histone deacetylases and facilitates fear extinction memory NC Hait, LE Wise, JC Allegood, M O'brien, D Avni, TM Reeves, PE Knapp, ... Nature neuroscience 17 (7), 971-980, 2014 | 234 | 2014 |
| Protection of skeletal muscles from ischemic injury: low-level laser therapy increases antioxidant activity D Avni, S Levkovitz, L Maltz, U Oron Photomedicine and Laser Therapy 23 (3), 273-277, 2005 | 156 | 2005 |
| Aberrant ORM (yeast)–like protein isoform 3 (ORMDL3) expression dysregulates ceramide homeostasis in cells and ceramide exacerbates allergic asthma in mice C Oyeniran, JL Sturgill, NC Hait, WC Huang, D Avni, M Maceyka, ... Journal of Allergy and Clinical Immunology 136 (4), 1035-1046. e6, 2015 | 119 | 2015 |
| Role of CREB in modulation of TNFα and IL-10 expression in LPS-stimulated RAW264. 7 macrophages D Avni, O Ernst, A Philosoph, T Zor Molecular immunology 47 (7-8), 1396-1403, 2010 | 115 | 2010 |
| The phosphorylated prodrug FTY720 is a histone deacetylase inhibitor that reactivates ERα expression and enhances hormonal therapy for breast cancer NC Hait, D Avni, A Yamada, M Nagahashi, T Aoyagi, H Aoki, CI Dumur, ... Oncogenesis 4 (6), e156-e156, 2015 | 112 | 2015 |
| Sphingosine-1-phosphate in chronic intestinal inflammation and cancer M Nagahashi, NC Hait, M Maceyka, D Avni, K Takabe, S Milstien, ... Advances in biological regulation 54, 112-120, 2014 | 95 | 2014 |
| Hepatic apolipoprotein M (apoM) overexpression stimulates formation of larger apoM/sphingosine 1-phosphate-enriched plasma high density lipoprotein M Liu, J Seo, J Allegood, X Bi, X Zhu, E Boudyguina, AK Gebre, D Avni, ... Journal of Biological Chemistry 289 (5), 2801-2814, 2014 | 90 | 2014 |
| Sphingosine-1-phosphate phosphatase 2 promotes disruption of mucosal integrity, and contributes to ulcerative colitis in mice and humans WC Huang, J Liang, M Nagahashi, D Avni, A Yamada, M Maceyka, ... The FASEB Journal 30 (8), 2945, 2016 | 63 | 2016 |
| The Phosphatidylinositol 3-kinase (PI3K) inhibitor LY294002 modulates cytokine expression in macrophages via p50 nuclear factor kappa B inhibition, in a PI3K-independent mechanism D Avni, Y Glucksam, T Zor Biochemical pharmacology 83 (1), 106-114, 2012 | 46 | 2012 |
| Synergistic IL-10 induction by LPS and the ceramide-1-phosphate analog PCERA-1 is mediated by the cAMP and p38 MAP kinase pathways M Goldsmith, D Avni, O Ernst, Y Glucksam, G Levy-Rimler, MM Meijler, ... Molecular immunology 46 (10), 1979-1987, 2009 | 44 | 2009 |
| Microalgae—Sustainable Source for Alternative Proteins and Functional Ingredients Promoting Gut and Liver Health Y Eilam, H Khattib, N Pintel, D Avni Global Challenges, 2200177, 2023 | 42 | 2023 |
| A ceramide‐1‐phosphate analogue, PCERA‐1, simultaneously suppresses tumour necrosis factor‐α and induces interleukin‐10 production in activated macrophages M Goldsmith, D Avni, G Levy‐Rimler, R Mashiach, O Ernst, M Levi, ... Immunology 127 (1), 103-115, 2009 | 42 | 2009 |
| Flavonoids-Macromolecules Interactions in Human Diseases with Focus on Alzheimer, Atherosclerosis and Cancer D Atrahimovich, D Avni, S Khatib Antioxidants 10 (3), 423, 2021 | 41 | 2021 |
| Photosynthetically controlled spirulina, but not solar spirulina, inhibits TNF-α secretion: potential implications for COVID-19-related cytokine storm therapy A Tzachor, O Rozen, S Khatib, S Jensen, D Avni Marine Biotechnology 23, 149-155, 2021 | 37 | 2021 |
| The ceramide‐1‐phosphate analogue PCERA‐1 modulates tumour necrosis factor‐α and interleukin‐10 production in macrophages via the cAMP–PKA–CREB pathway in a GTP‐dependent manner D Avni, MM Meijler, T Zor Immunology 129 (3), 375-385, 2010 | 35 | 2010 |
| Modulation of TNFα, IL-10 and IL-12p40 levels by a ceramide-1-phosphate analog, PCERA-1, in vivo and ex vivo in primary macrophages D Avni, M Goldsmith, O Ernst, R Mashiach, T Tuntland, MM Meijler, ... Immunology letters 123 (1), 1-8, 2009 | 33 | 2009 |
| Regulation of Cholesterol Metabolism by Phytochemicals Derived from Algae and Edible Mushrooms in Non-Alcoholic Fatty Liver Disease Y Eilam, N Pintel, H Khattib, N Shagug, R Taha, D Avni International Journal of Molecular Sciences 23 (22), 13667, 2022 | 28 | 2022 |
| Deletion or inhibition of SphK1 mitigates fulminant hepatic failure by suppressing TNFα-dependent inflammation and apoptosis D Avni, KB Harikumar, AJ Sanyal, S Spiegel FASEB journal: official publication of the Federation of American Societies …, 2021 | 17 | 2021 |
| Exogenous ceramide-1-phosphate (C1P) and phospho-ceramide analogue-1 (PCERA-1) regulate key macrophage activities via distinct receptors S Katz, O Ernst, D Avni, M Athamna, A Philosoph, L Arana, A Ouro, ... Immunology letters 169, 73-81, 2016 | 17 | 2016 |