High glucose induces Smad activation via the transcriptional coregulator p300 and contributes to cardiac fibrosis and hypertrophy A Bugyei-Twum, A Advani, SL Advani, Y Zhang, K Thai, DJ Kelly, ... Cardiovascular diabetology 13, 1-12, 2014 | 130 | 2014 |
Sirtuin 1 activation attenuates cardiac fibrosis in a rodent pressure overload model by modifying Smad2/3 transactivation A Bugyei-Twum, C Ford, R Civitarese, J Seegobin, SL Advani, ... Cardiovascular research 114 (12), 1629-1641, 2018 | 89 | 2018 |
Heart failure with preserved ejection fraction in diabetes: mechanisms and management P Meagher, M Adam, R Civitarese, A Bugyei-Twum, KA Connelly Canadian Journal of Cardiology 34 (5), 632-643, 2018 | 79 | 2018 |
Suppression of NLRP3 inflammasome activation ameliorates chronic kidney disease-induced cardiac fibrosis and diastolic dysfunction A Bugyei-Twum, A Abadeh, K Thai, Y Zhang, M Mitchell, G Kabir, ... Scientific reports 6 (1), 39551, 2016 | 51 | 2016 |
Substoichiometric inhibition of transthyretin misfolding by immune-targeting sparsely populated misfolding intermediates: a potential diagnostic and therapeutic for TTR amyloidoses NJ Galant, A Bugyei-Twum, R Rakhit, P Walsh, S Sharpe, PE Arslan, ... Scientific reports 6 (1), 25080, 2016 | 43 | 2016 |
Endothelial-specific loss of IFT88 promotes endothelial-to-mesenchymal transition and exacerbates bleomycin-induced pulmonary fibrosis S Singh, M Adam, PN Matkar, A Bugyei-Twum, JF Desjardins, HH Chen, ... Scientific Reports 10 (1), 4466, 2020 | 36 | 2020 |
Cardiovascular effects of incretins in diabetes A Advani, A Bugyei-Twum, KA Connelly Canadian journal of diabetes 37 (5), 309-314, 2013 | 34 | 2013 |
Valproic acid induces endothelial-to-mesenchymal transition-like phenotypic switching S Murugavel, A Bugyei-Twum, PN Matkar, H Al-Mubarak, HH Chen, ... Frontiers in Pharmacology 9, 737, 2018 | 30 | 2018 |
BReast CAncer susceptibility gene 2 deficiency exacerbates oxidized LDL‐induced DNA damage and endothelial apoptosis S Singh, H Nguyen, D Michels, H Bazinet, PN Matkar, Z Liu, L Esene, ... Physiological reports 8 (13), e14481, 2020 | 29 | 2020 |
Antibodies to TTR and methods of use A Chakrabartty, R Rakhit, AA Bugyei-Twum US Patent 9,534,048, 2017 | 29 | 2017 |
The Goto Kakizaki rat: Impact of age upon changes in cardiac and renal structure, function P Meagher, R Civitarese, X Lee, M Gordon, A Bugyei-Twum, ... Plos one 16 (6), e0252711, 2021 | 9 | 2021 |
BRCA2 is a novel regulator of endothelial cell function and apoptosis following oxidative stress M Adam, S Murugavel, A Bugyei-Twum, T Narang, S Jain, Y Pan, ... Atherosclerosis Supplements 32, 110, 2018 | 3 | 2018 |
Inhibition of transthyretin fibrillogenesis using a conformation specific antibody A Bugyei-Twum University of Toronto (Canada), 2012 | 3 | 2012 |
Sex differences in long‐term effects of exertional heat stroke on myocardial metabolism A Bugyei‐Twum The Journal of Physiology 598 (18), 3829-3830, 2020 | 2 | 2020 |
Antibodies to TTR and Methods of Use A Chakrabartty, R Rakhit, AA Bugyei-Twum US Patent App. 15/373,657, 2017 | 1 | 2017 |
Correction: Corrigendum: Substoichiometric inhibition of transthyretin misfolding by immune-targeting sparsely populated misfolding intermediates: a potential diagnostic and … NJ Galant, A Bugyei-Twum, R Rakhit, P Walsh, S Sharpe, PE Arslan, ... Scientific Reports 6 (1), 27679, 2016 | 1 | 2016 |
Antibodies to TTR and methods of use A Chakrabartty, R Rakhit, AA Bugyei-Twum US Patent 11,402,394, 2022 | | 2022 |
Myocardial Structure and Function in Heart Failure with Preserved Ejection Fraction: Molecular Insights and Therapeutic Strategies Targeting Transforming Growth Factor Beta … A Bugyei-Twum University of Toronto (Canada), 2022 | | 2022 |
Circulating Extracellular Vesicles From Mouse and Rat Models of Diabetes Reveal Specific Microrna Signatures as Biomarkers of Diabetic Cardiomyopathy M Chandy, MS Njock, S Veitch, A Bugyei-Twum, H Cheng, A Momen, ... Circulation 136 (suppl_1), A21261-A21261, 2017 | | 2017 |
The GLP-1 Receptor Agonist Liraglutide Improves Autophagy Impairment in the Diabetic Heart A Bugyei-Twum, J Switzer, KK Singh, KA Connelly Arteriosclerosis, Thrombosis, and Vascular Biology 37 (suppl_1), A368-A368, 2017 | | 2017 |