| Long non-coding RNAs as a source of new peptides J Ruiz-Orera, X Messeguer, JA Subirana, MM Alba elife 3, e03523, 2014 | 553 | 2014 |
| Extreme genomic erosion after recurrent demographic bottlenecks in the highly endangered Iberian lynx F Abascal, A Corvelo, F Cruz, JL Villanueva-Cañas, A Vlasova, ... Genome biology 17, 1-19, 2016 | 187 | 2016 |
| Standardized annotation of translated open reading frames JM Mudge, J Ruiz-Orera, JR Prensner, MA Brunet, F Calvet, I Jungreis, ... Nature biotechnology 40 (7), 994-999, 2022 | 165 | 2022 |
| Origins of De Novo Genes in Human and Chimpanzee J Ruiz-Orera, J Hernandez-Rodriguez, C Chiva, E Sabidó, I Kondova, ... PLoS genetics 11 (12), e1005721, 2015 | 162 | 2015 |
| Pathogenic variants damage cell composition and single cell transcription in cardiomyopathies D Reichart, EL Lindberg, H Maatz, AMA Miranda, A Viveiros, N Shvetsov, ... Science 377 (6606), eabo1984, 2022 | 145 | 2022 |
| Translation of neutrally evolving peptides provides a basis for de novo gene evolution J Ruiz-Orera, P Verdaguer-Grau, JL Villanueva-Cañas, X Messeguer, ... Nature ecology & evolution 2 (5), 890-896, 2018 | 132 | 2018 |
| Translation of small open reading frames: roles in regulation and evolutionary innovation J Ruiz-Orera, MM Albà Trends in Genetics 35 (3), 186-198, 2019 | 103 | 2019 |
| Evolutionary origins and interactomes of human, young microproteins and small peptides translated from short open reading frames CL Sandmann, JF Schulz, J Ruiz-Orera, M Kirchner, M Ziehm, E Adami, ... Molecular cell 83 (6), 994-1011. e18, 2023 | 83 | 2023 |
| Uncovering de novo gene birth in yeast using deep transcriptomics WR Blevins, J Ruiz-Orera, X Messeguer, B Blasco-Moreno, ... Nature communications 12 (1), 604, 2021 | 78 | 2021 |
| New genes and functional innovation in mammals JL Villanueva-Canas, J Ruiz-Orera, MI Agea, M Gallo, D Andreu, MM Albà Genome Biology and Evolution 9 (7), 1886-1900, 2017 | 69 | 2017 |
| Evolution of new proteins from translated sORFs in long non-coding RNAs J Ruiz-Orera, JL Villanueva-Cañas, MM Albà Experimental cell research 391 (1), 111940, 2020 | 53 | 2020 |
| Ribosome profiling at isoform level reveals evolutionary conserved impacts of differential splicing on the proteome M Reixachs-Solé, J Ruiz-Orera, MM Albà, E Eyras Nature communications 11 (1), 1768, 2020 | 53 | 2020 |
| Impairment of the ER/mitochondria compartment in human cardiomyocytes with PLN p. Arg14del mutation F Cuello, AE Knaust, U Saleem, M Loos, J Raabe, D Mosqueira, S Laufer, ... EMBO molecular medicine 13 (6), e13074, 2021 | 51 | 2021 |
| What can ribo-seq, immunopeptidomics, and proteomics tell us about the noncanonical proteome? JR Prensner, JG Abelin, LW Kok, KR Clauser, JM Mudge, J Ruiz-Orera, ... Molecular & Cellular Proteomics 22 (9), 2023 | 45 | 2023 |
| Evolution and implications of de novo genes in humans LA Broeils, J Ruiz-Orera, B Snel, N Hubner, S van Heesch Nature ecology & evolution 7 (6), 804-815, 2023 | 44 | 2023 |
| Conserved regions in long non-coding RNAs contain abundant translation and protein–RNA interaction signatures J Ruiz-Orera, MM Albà NAR Genomics and Bioinformatics 1 (1), e2-e2, 2019 | 41 | 2019 |
| Multifunctional RNA-binding proteins influence mRNA abundance and translational efficiency of distinct sets of target genes V Schneider-Lunitz, J Ruiz-Orera, N Hubner, S van Heesch PLoS Computational Biology 17 (12), e1009658, 2021 | 39 | 2021 |
| Translation of non-canonical open reading frames as a cancer cell survival mechanism in childhood medulloblastoma DA Hofman, J Ruiz-Orera, I Yannuzzi, R Murugesan, A Brown, ... Molecular Cell 84 (2), 261-276. e18, 2024 | 34 | 2024 |
| pTINCR microprotein promotes epithelial differentiation and suppresses tumor growth through CDC42 SUMOylation and activation O Boix, M Martinez, S Vidal, M Giménez-Alejandre, L Palenzuela, ... Nature communications 13 (1), 6840, 2022 | 34 | 2022 |
| Impact of uORFs in mediating regulation of translation in stress conditions SG Moro, C Hermans, J Ruiz-Orera, MM Albà BMC molecular and cell biology 22, 1-13, 2021 | 34 | 2021 |