| Sex differences in high‐fat diet‐induced obesity, metabolic alterations and learning, and synaptic plasticity deficits in mice LL Hwang, CH Wang, TL Li, SD Chang, LC Lin, CP Chen, CT Chen, ... Obesity 18 (3), 463-469, 2010 | 473 | 2010 |
| Mechanisms of the antinociceptive action of gabapentin JK Cheng, LC Chiou Journal of pharmacological sciences 100 (5), 471-486, 2006 | 343 | 2006 |
| Orexin/hypocretin role in reward: implications for opioid and other addictions C Baimel, SE Bartlett, LC Chiou, AJ Lawrence, JW Muschamp, O Patkar, ... British journal of pharmacology 172 (2), 334-348, 2015 | 214 | 2015 |
| Activation of orexin 1 receptors in the periaqueductal gray of male rats leads to antinociception via retrograde endocannabinoid (2-arachidonoylglycerol)-induced disinhibition YC Ho, HJ Lee, LW Tung, YY Liao, SY Fu, SF Teng, HT Liao, K Mackie, ... Journal of Neuroscience 31 (41), 14600-14610, 2011 | 188 | 2011 |
| Nociceptin/orphanin FQ peptide receptors: pharmacology and clinical implications LC Chiou, YY Liao, PC Fan, PH Kuo, CH Wang, C Riemer, EP Prinssen Current drug targets 8 (1), 117-135, 2007 | 173 | 2007 |
| Orexins depolarize rostral ventrolateral medulla neurons and increase arterial pressure and heart rate in rats mainly via orexin 2 receptors SC Huang, YWE Dai, YH Lee, LC Chiou, LL Hwang Journal of Pharmacology and Experimental Therapeutics 334 (2), 522-529, 2010 | 124 | 2010 |
| Orexins contribute to restraint stress-induced cocaine relapse by endocannabinoid-mediated disinhibition of dopaminergic neurons LW Tung, GL Lu, YH Lee, L Yu, HJ Lee, E Leishman, H Bradshaw, ... Nature communications 7 (1), 12199, 2016 | 119 | 2016 |
| Docosahexaenoic acid inhibits synaptic transmission and epileptiform activity in the rat hippocampus C Young, PW Gean, LC Chiou, YZ Shen Synapse 37 (2), 90-94, 2000 | 116 | 2000 |
| Orexins/hypocretins: pain regulation and cellular actions LC Chiou, HJ Lee, YC Ho, SP Chen, YY Liao, CH Ma, PC Fan, JL Fuh, ... Current pharmaceutical design 16 (28), 3089-3100, 2010 | 104 | 2010 |
| Antiallodynic effects of intrathecal orexins in a rat model of postoperative pain JK Cheng, RCC Chou, LL Hwang, LC Chiou Journal of Pharmacology and Experimental Therapeutics 307 (3), 1065-1071, 2003 | 89 | 2003 |
| Targeting the cannabinoid system for pain relief? LC Chiou, SSJ Hu, YC Ho Acta Anaesthesiologica Taiwanica 51 (4), 161-170, 2013 | 85 | 2013 |
| Mediation of amphetamine-induced long-term depression of synaptic transmission by CB1 cannabinoid receptors in the rat amygdala YC Huang, SJ Wang, LC Chiou, PW Gean Journal of Neuroscience 23 (32), 10311-10320, 2003 | 73 | 2003 |
| Median nerve stimulation induces analgesia via orexin-initiated endocannabinoid disinhibition in the periaqueductal gray YH Chen, HJ Lee, MT Lee, YT Wu, YH Lee, LL Hwang, MS Hung, ... Proceedings of the National Academy of Sciences 115 (45), E10720-E10729, 2018 | 72 | 2018 |
| Capsaicin in the periaqueductal gray induces analgesia via metabotropic glutamate receptor‐mediated endocannabinoid retrograde disinhibition HT Liao, HJ Lee, YC Ho, LC Chiou British journal of pharmacology 163 (2), 330-345, 2011 | 71 | 2011 |
| Chinese herb constituent β-eudesmol alleviated the electroshock seizures in mice and electrographic seizures in rat hippocampal slices LC Chiou, JY Ling, CC Chang Neuroscience Letters 231 (3), 171-174, 1997 | 70 | 1997 |
| Hypofunction of glutamatergic neurotransmission in the periaqueductal gray contributes to nerve-injury-induced neuropathic pain YC Ho, JK Cheng, LC Chiou Journal of Neuroscience 33 (18), 7825-7836, 2013 | 69 | 2013 |
| Design and Synthesis of Novel Deuterated Ligands Functionally Selective for the γ-Aminobutyric Acid Type A Receptor (GABAAR) α6 Subtype with Improved … DE Knutson, R Kodali, B Divović, M Treven, MR Stephen, NM Zahn, ... Journal of medicinal chemistry 61 (6), 2422-2446, 2018 | 65 | 2018 |
| Mechanism underlying increased neuronal activity in the rat ventrolateral periaqueductal grey by a μ-opioid LC Chiou, LYM Huang The Journal of physiology 518 (Pt 2), 551, 1999 | 65 | 1999 |
| Stress induces analgesia via orexin 1 receptor-initiated endocannabinoid/CB1 signaling in the mouse periaqueductal gray HJ Lee, LY Chang, YC Ho, SF Teng, LL Hwang, K Mackie, LC Chiou Neuropharmacology 105, 577-586, 2016 | 64 | 2016 |
| Elevated plasma orexin A levels in a subgroup of patients with schizophrenia associated with fewer negative and disorganized symptoms YL Chien, CM Liu, JC Shan, HJ Lee, MH Hsieh, HG Hwu, LC Chiou Psychoneuroendocrinology 53, 1-9, 2015 | 59 | 2015 |
