| Enhanced learning and memory and altered GABAergic synaptic transmission in mice lacking the α5 subunit of the GABAAReceptor N Collinson, FM Kuenzi, W Jarolimek, KA Maubach, R Cothliff, C Sur, ... Journal of Neuroscience 22 (13), 5572-5580, 2002 | 786 | 2002 |
| Reducing safety-related drug attrition: the use of in vitro pharmacological profiling J Bowes, AJ Brown, J Hamon, W Jarolimek, A Sridhar, G Waldron, ... Nature reviews Drug discovery 11 (12), 909-922, 2012 | 779 | 2012 |
| A physiological role for GABAB receptors and the effects of baclofen in the mammalian central nervous system U Misgeld, M Bijak, W Jarolimek Progress in neurobiology 46 (4), 423-462, 1995 | 605 | 1995 |
| Molecular Determinants of Dofetilide Block of HERG K+ Channels E Ficker, W Jarolimek, J Kiehn, A Baumann, AM Brown Circulation research 82 (3), 386-395, 1998 | 354 | 1998 |
| A furosemide-sensitive K+–Cl− cotransporter counteracts intracellular Cl− accumulation and depletion in cultured rat midbrain neurons W Jarolimek, A Lewen, U Misgeld Journal of Neuroscience 19 (12), 4695-4704, 1999 | 206 | 1999 |
| Mannitol Enhances Antibiotic Sensitivity of Persister Bacteria in Pseudomonas aeruginosa Biofilms N Barraud, A Buson, W Jarolimek, SA Rice PloS one 8 (12), e84220, 2013 | 193 | 2013 |
| Nanoscale dysregulation of collagen structure-function disrupts mechano-homeostasis and mediates pulmonary fibrosis MG Jones, OG Andriotis, JJW Roberts, K Lunn, VJ Tear, L Cao, K Ask, ... Elife 7, e36354, 2018 | 154 | 2018 |
| Functional properties of the high-affinity TRPV1 (VR1) vanilloid receptor antagonist (4-hydroxy-5-iodo-3-methoxyphenylacetate ester) iodo-resiniferatoxin GR Seabrook, KG Sutton, W Jarolimek, GJ Hollingworth, S Teague, ... Journal of Pharmacology and Experimental Therapeutics 303 (3), 1052-1060, 2002 | 154 | 2002 |
| Pre-clinical evaluation of small molecule LOXL2 inhibitors in breast cancer J Chang, MC Lucas, LE Leonte, M Garcia-Montolio, LB Singh, AD Findlay, ... Oncotarget 8 (16), 26066, 2017 | 127 | 2017 |
| The lysyl oxidase like 2/3 enzymatic inhibitor, PXS‐5153A, reduces crosslinks and ameliorates fibrosis H Schilter, AD Findlay, L Perryman, TT Yow, J Moses, A Zahoor, CI Turner, ... Journal of cellular and molecular medicine 23 (3), 1759-1770, 2019 | 110 | 2019 |
| Neurological phenotype and synaptic function in mice lacking the CaV1. 3 α subunit of neuronal L-type voltage-dependent Ca2+ channels NC Clark, N Nagano, FM Kuenzi, W Jarolimek, I Huber, D Walter, ... Neuroscience 120 (2), 435-442, 2003 | 105 | 2003 |
| Molecular Determinants of Inactivation and Dofetilide Block inether a-go-go (EAG) Channels and EAG-Related K+ Channels E Ficker, W Jarolimek, AM Brown Molecular pharmacology 60 (6), 1343-1348, 2001 | 105 | 2001 |
| Activity dependent alkaline and acid transients in guinea pig hippocampal slices W Jarolimek, U Misgeld, HD Lux Brain research 505 (2), 225-232, 1989 | 91 | 1989 |
| Effects of an anti-inflammatory VAP-1/SSAO inhibitor, PXS-4728A, on pulmonary neutrophil migration HC Schilter, A Collison, RC Russo, JS Foot, TT Yow, AT Vieira, ... Respiratory Research 16, 1-14, 2015 | 69 | 2015 |
| PXS-4681A, a potent and selective mechanism-based inhibitor of SSAO/VAP-1 with anti-inflammatory effects in vivo JS Foot, TT Yow, H Schilter, A Buson, M Deodhar, AD Findlay, L Guo, ... Journal of Pharmacology and Experimental Therapeutics 347 (2), 365-374, 2013 | 68 | 2013 |
| GABAB receptor-mediated inhibition of tetrodotoxin-resistant GABA release in rodent hippocampal CA1 pyramidal cells W Jarolimek, U Misgeld Journal of Neuroscience 17 (3), 1025-1032, 1997 | 64 | 1997 |
| Identification and optimization of mechanism-based fluoroallylamine inhibitors of lysyl oxidase-like 2/3 AD Findlay, JS Foot, A Buson, M Deodhar, AG Jarnicki, PM Hansbro, ... Journal of Medicinal Chemistry 62 (21), 9874-9889, 2019 | 49 | 2019 |
| The inhibitor of semicarbazide‐sensitive amine oxidase, PXS‐4728A, ameliorates key features of chronic obstructive pulmonary disease in a mouse model AG Jarnicki, H Schilter, G Liu, K Wheeldon, AT Essilfie, JS Foot, TT Yow, ... British journal of pharmacology 173 (22), 3161-3175, 2016 | 45 | 2016 |
| A first-in-class pan-lysyl oxidase inhibitor impairs stromal remodeling and enhances gemcitabine response and survival in pancreatic cancer JL Chitty, M Yam, L Perryman, AL Parker, JN Skhinas, YFI Setargew, ... Nature Cancer 4 (9), 1326-1344, 2023 | 41 | 2023 |
| Neurons sensitive to pH in slices of the rat ventral medulla oblongata W Jarolimek, U Misgeld, HD Lux Pflügers Archiv 416, 247-253, 1990 | 41 | 1990 |
